A test to check if patients are taking their HIV medication as prescribed
Official title: Urine tenofovir point-of-care test to identify patients in need of ART adherence support
Funded at Stellenbosch University · NIH-10884290 · Data updated 2026-11-12
This study is working on a simple and affordable test that uses urine samples to quickly check if people with HIV are taking their medication as prescribed, so doctors can give them the support they need to stay healthy.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stellenbosch University NIH-funded |
| Lab location | 1 site (Stellenbosch, SOUTH AFRICA) |
| Project start | July 7, 2020 |
| Project end | June 30, 2026 |
| Funding year | 2024 |
| Award (this year) | $326,142 |
| NIH project number | 5R01AI152119-05 |
| Project ID | NIH-10884290 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals living with HIV who are currently on antiretroviral therapy.
✕Less likely to help
Patients who are not on antiretroviral therapy or those who are not living with HIV may not benefit from this research.
What this research studies
This research focuses on developing a low-cost point-of-care test that measures adherence to antiretroviral therapy (ART) for individuals living with HIV. By using urine samples, the test aims to provide immediate feedback on whether patients are taking their medication correctly. This approach allows healthcare providers to offer timely support and interventions to improve adherence, ultimately helping to prevent treatment failure and the spread of HIV. The goal is to make this testing accessible in resource-limited settings, enhancing patient care.
Why it matters
Potential benefit: If successful, this research could lead to improved adherence to HIV treatment, resulting in better health outcomes and reduced transmission of the virus.
How similar studies have gone: Other research has shown promise in using point-of-care tests for medication adherence, indicating that this approach could be effective.
Where this research is happening
-
Stellenbosch University
Stellenbosch, South Africa Active
Researchers
- Principal investigator: Van Zyl, Gert Uves — Stellenbosch University
- Study coordinator: Van Zyl, Gert Uves
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.