Assessing heart health in HIV-infected individuals before and after starting treatment
Official title: Cardiovascular magnetic resonance assessment of subclinicalcardiovascular abnormalities before and after the initiation of antiretroviral therapy in HIV-infected South Africans
Funded at Stellenbosch University · NIH-10998099 · Data updated 2026-11-12
This study is looking at heart health in people with HIV in South Africa to find any early signs of heart problems before they start treatment, and it will also see how starting treatment affects their heart over time, all while helping local doctors learn better ways to spot and treat these issues.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stellenbosch University NIH-funded |
| Lab location | 1 site (Stellenbosch, SOUTH AFRICA) |
| Project start | September 11, 2024 |
| Project end | August 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $100,559 |
| NIH project number | 1K43TW012849-01 |
| Project ID | NIH-10998099 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are HIV-infected individuals in South Africa who have not yet started antiretroviral therapy.
✕Less likely to help
Patients who are already on antiretroviral therapy or those without HIV may not benefit from this research.
What this research studies
This research investigates cardiovascular health in people living with HIV in South Africa, focusing on heart abnormalities that may exist before they start antiretroviral therapy (ART). Using advanced cardiovascular magnetic resonance imaging (CMR), the study aims to identify early signs of heart disease that could lead to serious health issues if not addressed. The research will also explore how starting ART affects these heart conditions over time. By training local healthcare professionals in CMR techniques, the project seeks to improve diagnosis and treatment in underserved areas.
Why it matters
Potential benefit: If successful, this research could lead to better early detection and management of cardiovascular diseases in HIV-infected patients, potentially reducing mortality rates.
How similar studies have gone: Previous research has shown that advanced imaging techniques like CMR can effectively identify cardiovascular issues in various populations, suggesting potential success for this approach in HIV-infected individuals.
Where this research is happening
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Stellenbosch University
Stellenbosch, South Africa Active
Researchers
- Principal investigator: Robbertse, Pieter-Paul Strauss — Stellenbosch University
- Study coordinator: Robbertse, Pieter-Paul Strauss
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.