Condition

Resilience clinical trials and research

• 13Clinical trials
• 469NIH research projects
• 9Countries

Newest Resilience clinical trials

All recruiting trials (13)

• Student Midwife Support Circle to reduce burnout and strengthen resilience and professional belonging

  This project will try a Student Midwife Support Circle with midwifery students to see if it lowers burnout and increases resilience and a sense of professional belonging.

  Recruiting Amasya University · Amasya, Center · NCT07583199

• Operating room black box–supported team debriefing to improve OR staff wellbeing and teamwork

  This project tests whether using an operating room 'black box' to support team debriefings helps OR staff reduce stress, strengthen teamwork, and increase psychological safety.

  Recruiting ORNND - Operating Room Nurse Network Denmark · Copenhagen and 2 other locations · NCT07396675

• The Coma Family Program: a resilience program for caregivers of patients with severe brain injury

  This program tests whether the Coma Family Program can better reduce emotional distress in caregivers of patients with severe acute brain injury compared to a health education control.

  Recruiting at 3 sites Icahn School of Medicine at Mount Sinai · Baltimore, Maryland and 3 other locations · NCT07331324

• Life skills training for Soldiers at their first duty station

  This project tests whether a mobile-delivered, military-tailored life skills program called Level Up can help Soldiers arriving at their first duty station reduce suicidal and other harmful behaviors and improve mental health.

  Recruiting Uniformed Services University of the Health Sciences · Fort Hood, Texas · NCT07286955

• Group gamified instrumental music training to boost resilience in underprivileged 8–12 year olds

  This program will test whether group gamified instrumental music lessons can help underprivileged Hong Kong children aged 8–12 become more resilient and reduce symptoms of depression and anxiety.

  Recruiting Chinese University of Hong Kong · Hong Kong · NCT07165925

• Recovering Together After Cardiac Arrest: a mind-body resilience program for survivors and caregivers.

  This project will try two brief mind-body programs to help cardiac arrest survivors and their caregivers reduce anxiety, depression, and emotional distress.

  Recruiting Icahn School of Medicine at Mount Sinai · Boston, Massachusetts and 1 other locations · NCT07143357

• Support program for Hong Kong–Shenzhen cross-boundary families

  This program tests whether group emotion-regulation and electronics-use sessions for Shenzhen-based parent–child pairs can help them become more resilient, reduce family conflict, and improve well-being.

  Recruiting City University of Hong Kong · Shenzhen, Guangdong · NCT07136064

• Five-session group skills training to build mental toughness for active-duty Soldiers

  This study will test whether a five-session group program called Life Force can strengthen mental toughness and reduce harmful or high-risk behaviors in active-duty Soldiers at Fort Hood.

  Recruiting Uniformed Services University of the Health Sciences · Killeen, Texas · NCT07050238

• Resilience versus physical activity to improve early childhood educators' well-being

  This project will test whether a remote resilience program or a remote physical activity program helps early childhood education staff improve their well-being.

  Recruiting University of North Carolina, Chapel Hill · Chapel Hill, North Carolina · NCT06919952

• A program to reduce violence against girls in Pakistan through life skills education

  This study is testing a program that teaches life skills to students in Pakistan to help reduce violence against girls by changing harmful social norms.

  Recruiting at 2 sites Aga Khan University · Karachi, Sindh and 1 other locations · NCT06777849

• Mobile app to promote mental well-being and resilience in Vietnamese youth

  This study is testing a new mobile app designed to help 10th graders in Vietnam improve their mental well-being and resilience while reducing stress.

  Recruiting University of British Columbia · Hanoi · NCT06753344

• Online eCoaching to help family caregivers boost wellbeing and resilience

  This 6-week program will test whether an online self-help eCoaching course can reduce stress and depressive symptoms and increase confidence for family caregivers of older adults in Hong Kong.

  Recruiting The University of Hong Kong · Hong Kong · NCT06604481

• Improving mental wellbeing in university students using LifeHack

  This study is testing if an online program called LifeHack can help university students improve their mental wellbeing through guided activities based on cognitive behavioral therapy.

  Recruiting at 2 sites Universiteit Leiden · Amsterdam and 1 other locations · NCT06423417

NIH-funded research (newest 40 of 469)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Cognitive SuperAging: Exploring why some octogenarians stay sharp in memory

  This NIH grant studies why a small group of people aged 80+ keep memory skills as good as much younger people, hoping to understand how to protect memory as we age.

  NIH research University of Chicago · Chicago, United States · NIH-11623260

• National Neighborhood Data Archive helps researchers study aging health in U.S. neighborhoods

  A nationwide data resource will help researchers understand how where people live affects health and aging, with a focus on respiratory illnesses in older adults.

  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11612338

• Understanding how neurons resist and recover from toxic chemicals

  Researchers are studying how brain cells fight back against harmful chemicals to help people survive exposure.

  NIH research University of California, San Diego · La Jolla, United States · NIH-11609312

• Fostering Community Connections to Strengthen Youth Resilience and Well-Being

  A Hawaii-based effort helps teens and young adults get mental health and preventive care more easily by building local networks and smart referral pathways.

  NIH research Waianae Coast Comprehensive Health Ctr · Waianae, United States · NIH-11578589

• Indigenous healthy homes and communities to improve health and resilience

  A community-led effort in Indigenous communities in the US Southwest aims to improve housing and health, focusing on safer homes, cleaner indoor environments, and access to culturally competent care.

  NIH research Albuquerque Area Indian Health Board · Albuquerque, United States · NIH-11578583

• Neural Circuitry Resilience in Psychotic Disorders

  Researchers are using ultra-high-field brain scans to understand how brain networks in people with schizophrenia adapt over time, with the goal of finding new ways to improve thinking and daily functioning.

  NIH research Veterans Health Administration · Pittsburgh, United States · NIH-11563768

• Gene-environment factors shaping Alzheimer's risk across life (twin study)

  This project studies how modifiable lifestyle and environmental factors, viewed through twin data, influence the risk of Alzheimer’s disease and related dementias across different stages of life.

  NIH research University of Colorado · Boulder, UNITED STATES · NIH-11543311

• Genetic and single-cell study of Alzheimer’s risk and resilience

  Researchers will study how genes and cell-level signals contribute to Alzheimer’s risk and resilience, using human brains and mouse models to find clues for therapies.

  NIH research Washington University · Saint Louis, United States · NIH-11539245

• Sleep and aging brain resilience in a short-lived vertebrate model

  A young-aged-friendly project explores how sleep quality affects brain health during aging, using a tiny, fast-lived fish model to understand Alzheimer’s-related changes.

  NIH research Princeton University · Princeton, UNITED STATES · NIH-11539189

• Project STRIVE: Mindful self-regulation to support resilient students

  A mindfulness-based program is tested with BIPOC students who are academically striving to see if it helps balance academic success with better physical and mental health.

  NIH research University of California Los Angeles · Los Angeles, United States · NIH-11538100

• How speaking two languages affects memory and brain aging

  This project looks at whether lifelong bilingualism helps protect thinking skills and the brain in people at risk for Alzheimer’s and related dementias.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11517212

• CC16 in childhood and resilience to early airflow limitation in adult life

  A long-term study looks at whether a lung-protective protein called CC16 in children helps prevent early breathing problems that can lead to COPD in adulthood.

  NIH research University of Arizona · Tucson, United States · NIH-11511727

• CC16 and resilience to early airflow limitation from childhood to adulthood

  A study looking at how a protein in the lungs (CC16) might protect children with early lung issues from developing airway problems later in life.

  NIH research University of Arizona · Tucson, United States · NIH-11511726

• CC16 and resilience to early lung problems into adulthood

  A study from the University of Arizona looks at whether a small lung protein called CC16 helps protect children with early signs of breathing problems from developing COPD-related issues later in life.

  NIH research University of Arizona · Tucson, United States · NIH-11511725

• CC16 in childhood and resilience to early airflow limitation in adulthood

  This grant explores how a protein called CC16 in childhood may protect against early lung problems that can lead to COPD later in life.

  NIH research University of Arizona · Tucson, United States · NIH-11511724

• CC16 in childhood and resilience to early airflow limitation in adult life

  A study to understand how a protein called CC16 may protect children with early airway issues from developing breathing problems later in life.

  NIH research University of Arizona · Tucson, United States · NIH-11511723

• Malaria Reservoir Study II: reducing parasite diversity to help eliminate malaria

  A study in West Africa aims to see if lowering the variety of malaria parasite strains can make elimination efforts more effective for communities living in high-transmission areas.

  NIH research New York University · New York, United States · NIH-11494914

• Malaria Reservoir Study II: lowering parasite variety to help elimination in high-transmission areas

  A study in Ghana aims to see if reducing the variety of malaria parasite strains can help limit transmission and move toward elimination, especially in places with high malaria pressure.

  NIH research New York University · New York, United States · NIH-11494913

• Bilingualism and language resilience in Hispanic people with primary progressive aphasia

  Researchers compare different bilingual experiences to see how they relate to language decline and thinking skills in Hispanic adults with primary progressive aphasia.

  NIH research University of Texas at Austin · Austin, United States · NIH-11491123

• How growing up poor in rural Georgia affects children's brains and risk for drug use

  This project looks at how early poverty and stress in rural Georgia change children's brain systems and their later chances of using drugs.

  NIH research University of Georgia · Athens, United States · NIH-11482288

• Adversities and resilience in young adults: a long-term study in Malawi and its effects on health and families

  This grant funds a long-term study of how difficult childhood experiences affect health, relationships, and parenting in young adults in Malawi and how these effects may pass to the next generation.

  NIH research State University New York Stony Brook · Stony Brook, United States · NIH-11474353

• How life circumstances affect brain aging in people with end-stage kidney disease

  This project looks at how neighborhood, income, education, and personal resilience relate to earlier memory and thinking problems in adults with end-stage kidney disease.

  NIH research New York University School of Medicine · New York, United States · NIH-11472074

• Speaking two languages and brain health in aging and Alzheimer's

  This project will look at whether speaking two or more languages helps protect thinking skills and brain structure in older adults, including people with Alzheimer’s disease.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11472064

• How common gene differences change reactions to chemical and biological toxins

  This project uses gene-editing screens to find common DNA differences that change how people's cells respond to chemical and biological toxins.

  NIH research University of Florida · Gainesville, United States · NIH-11471388

• How biological aging and blood proteins relate to thinking after a stroke

  This project looks at whether measures of biological aging and patterns of blood proteins help explain which stroke survivors keep their thinking sharp and which go on to develop vascular dementia.

  NIH research University of Florida · Gainesville, United States · NIH-11470695

• Mental health and coping for teens who leave home without a parent

  This work looks at how hunger and violence affect the mental health and coping of teens (about ages 15–19) who leave home without a parent.

  NIH research Columbia University Health Sciences · New York, United States · NIH-11458640

• Neurobiological signs of resilience and recovery from substance abuse in youth who faced childhood adversity

  A long-term study will explore brain patterns in young people who faced childhood adversity to understand why some stay resilient and avoid substance problems.

  NIH research Mclean Hospital · Belmont, United States · NIH-11458394

• Behavioral health and resilience of Venezuelan families in the U.S. and Colombia

  This project looks at how migration-related stress affects depression and alcohol use among Venezuelan parents and adolescents living in the United States and Colombia.

  NIH research University of Florida · Gainesville, United States · NIH-11455254

• Coalition for Health, Resilience and Prevention: A hub-and-spoke model to bring prevention services to rural clinics

  A large NIH grant aims to help rural clinics in the U.S. put proven overdose prevention and health resilience services into practice through a hub-and-spoke networking approach.

  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11454669

• NAD in nerve cells: keeping mitochondria healthy to fight aging-related brain disease

  Aerospace approach to protect neurons by boosting mitochondrial NAD to help people at risk of ALS, motor neuron disease, and ataxia—seeking to keep nerve cells alive and connected as we age.

  NIH research Washington University · Saint Louis, United States · NIH-11448240

• Understanding and improving support for male dementia caregivers

  This project focuses on what helps or hinders men who care for people with dementia, with new ideas to reach and support them better.

  NIH research University of Louisville · Louisville, United States · NIH-11444413

• Strengthening teen brain resilience with music during cancer treatment

  A pilot program tests whether 10 weeks of online ukulele lessons led by certified music therapists can help teens undergoing radiation therapy maintain cognitive and emotional resilience.

  NIH research Mayo Clinic Arizona · Scottsdale, United States · NIH-11444371

• A Hidden Hormone That May Help Preserve Thinking as We Age

  A small exploratory study in adults 21+ looks at whether the hormone ADIOL could protect thinking skills as people age, especially in the context of Alzheimer’s risk.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11442545

• Dimensional Complexity as a Brain Biomarker for Resilience in Aging and Dementia

  A biomarker from resting-state brain scans may help predict which people are likely to stay cognitively healthy as they age.

  NIH research Henry Ford Health + Michigan State University Health Sciences · East Lansing, United States · NIH-11426661

• Maui wildfire exposure: health and resilience cohort

  A long-term study of Maui residents to understand how wildfires affect health and well-being and to help communities recover.

  NIH research University of Hawaii at Manoa · Honolulu, United States · NIH-11423023

• Promoting Coping Skills to Reduce Health Gaps in Teens and Young Adults

  A study tests a shift-and-persist coping approach to help racial/ethnic minority teens and young adults handle stress and reduce risks for chronic disease.

  NIH research University of California Riverside · Riverside, United States · NIH-11422424

• Prenatal chemical exposures and childhood depression risk

  This project looks at how exposure to flame retardant chemicals before birth and in early childhood may influence depression in mothers and their kids over the first eight years.

  NIH research Washington University · Saint Louis, United States · NIH-11422350

• Resilience training to support first responders' mental health

  A large trial will test a 4-hour resilience workshop designed to help first responders cope with trauma and reduce PTSD and depression symptoms.

  NIH research State University New York Stony Brook · Stony Brook, United States · NIH-11421527

• Helping Advanced Cancer Patients and Families Plan Ahead with a Resilience-Building Web Program

  A web-based resilience program is being tested to help people with advanced cancer and their family caregivers have meaningful conversations and complete advance directives.

  NIH research University of Illinois at Chicago · Chicago, UNITED STATES · NIH-11417326

• Resilience endotypes and early ARDS detection using biomarkers and AI

  A Duke University team is using biomarkers and smart data analysis to detect ARDS early and uncover patterns that predict how patients recover.

  NIH research Duke University · Durham, United States · NIH-11416345

Related topics

Quick answers

How many Resilience clinical trials are recruiting right now?

13, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 9 countries. The most sites are in United States (5 trials), Hong Kong (2 trials), Netherlands (2 trials), Denmark (1 trial), Germany (1 trial). Each study page lists its sites and which ones are recruiting.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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