How growing up poor in rural Georgia affects children's brains and risk for drug use

Early Adversity and Drug Use Vulnerability Among Low Income Rural Children: Testing a Neuro-ecological Model of Resilience

NIH-funded research University of Georgia · NIH-11482288

This project looks at how early poverty and stress in rural Georgia change children's brain systems and their later chances of using drugs.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Georgia NIH-funded
Lab location1 site (Athens, United States)
Project IDNIH-11482288 on NIH RePORTER

What this research studies

If your child joins, researchers will follow low-income children in rural Georgia starting around age 7 and collect information over several years. They will combine brain scans, cognitive and behavioral tests, and surveys about family and community stressors and supports. The team will study how brain systems that control thinking and emotion respond to those experiences and whether those patterns relate to later drug-use risk. The approach mixes neuroscience with real-world community factors to understand what helps or harms children in rural settings.

Who could benefit from this research

Good fit: Ideal participants are low-income children living in rural Georgia, beginning around age 7, whose families can attend repeated in-person visits and testing sessions.

Not a fit: This project is unlikely to directly help adults, children from urban areas, or people already in drug-treatment programs seeking immediate therapy.

Why it matters

Potential benefit: If successful, this work could reveal early brain and environmental signs of drug-use risk so prevention and support can reach children sooner.

How similar studies have performed: Prior studies link early adversity to brain changes and later substance use, but combining detailed brain scans with rural community measures in a long-term design is relatively new.

Where this research is happening

Athens, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.