Condition

Coma clinical trials and research

• 10Clinical trials
• 5NIH research projects
• 6Countries

Newest Coma clinical trials

All recruiting trials (10)

• Recovery after coma from serious brain injury or illness

  This observational study will follow adults who are unconscious due to a serious brain illness or injury to see what medical, neurological, psychological, and social factors are linked with recovery over time.

  Recruiting University of California, San Francisco · San Francisco, California · NCT07614074

• Can a bedside brain scan (fNIRS) detect activity in healthy people and in people with disorders of consciousness

  This observational study tests whether functional near-infrared spectroscopy (fNIRS) can measure brain activity at the bedside in healthy adults and in patients with disorders of consciousness in the Neuro-ICU.

  Recruiting University of California, Los Angeles · Los Angeles, California · NCT07485361

• The Coma Family Program: a resilience program for caregivers of patients with severe brain injury

  This program tests whether the Coma Family Program can better reduce emotional distress in caregivers of patients with severe acute brain injury compared to a health education control.

  Recruiting at 3 sites Icahn School of Medicine at Mount Sinai · Baltimore, Maryland and 3 other locations · NCT07331324

• AI to improve telephone triage for emergency calls at CCUE Andalucía

  This project tests AI tools to help emergency call operators spot life-threatening problems like cardiac arrest, stroke, severe breathing trouble, and chest pain.

  Recruiting Centro de Emergencias Sanitarias 061 Andalucía · Málaga, Málaga · NCT07247669

• Brain MRI connectivity after cardiac arrest using mobile and high-field scanners

  This study tests whether mobile very low field MRI at the bedside and traditional high-field MRI can map brain structure after cardiac arrest to help predict outcomes.

  Recruiting University Hospital, Toulouse · Toulouse · NCT07177755

• Combined whole-brain MRI to predict recovery after cardiac arrest

  This study tests whether personalized whole-brain MRI connectivity maps can better predict six-month neurological recovery in adults who remain unconscious after cardiac arrest compared with standard predictors.

  Recruiting University Hospital, Toulouse · Toulouse · NCT06617377

• Using Rapid-Response EEG to Diagnose Seizures in Children

  This study is testing if a new quick EEG device can help doctors diagnose seizures in children faster than the standard method.

  Recruiting Children's Hospital at Montefiore · The Bronx, New York · NCT06564662

• Treatment for brain activity issues after cardiac arrest

  This study tests if giving anti-seizure medication to comatose patients after cardiac arrest can help them recover better than those who don’t receive it.

  Recruiting at 17 sites University of Twente · Brussels and 20 other locations · NCT06549426

• Cervical spinal cord stimulation for patients with disorders of consciousness after brain hemorrhage

  This study tests if a new treatment using spinal cord stimulation can help patients who are not fully awake after a brain bleed become more alert and aware.

  Recruiting Beijing Tiantan Hospital · Beijing, Beijing Municipality · NCT05922644

• Predicting outcomes for comatose patients after cardiac arrest

  This study is trying to see if a new method can help doctors predict how well comatose patients will recover after a cardiac arrest by using different tests and a special algorithm.

  Recruiting at 6 sites Assistance Publique - Hôpitaux de Paris · Bobigny and 6 other locations · NCT05321459

NIH-funded research (5)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Understanding coma in cerebral malaria and the brain chemistry behind it

  Researchers are studying why some children with cerebral malaria fall into coma, focusing on a brain chemical called pipecolic acid and how it might affect brain activity.

  NIH research Albert Einstein College of Medicine · Bronx, United States · NIH-11377368

• Understanding Coma in Children with Cerebral Malaria

  This research aims to discover why children with cerebral malaria fall into a coma by looking at a specific chemical in their blood.

  NIH research Albert Einstein College of Medicine · Bronx, United States · NIH-11122225

• Understanding how brain signals can help recover patients from coma

  This study is looking at how certain brain connections can help people recover from a coma after a serious brain injury, using rats to learn more about how brain cells work together during the early recovery phase, with the hope of finding new ways to help patients heal better.

  NIH research Massachusetts General Hospital · Boston, United States · NIH-11093463

• Understanding how coma occurs in children with cerebral malaria

  This study is looking into how a substance called pipecolic acid might affect the brains of children in a coma due to severe malaria, with the hope of finding new ways to help them recover.

  NIH research Albert Einstein College of Medicine · Bronx, United States · NIH-10848352

• Using EEG to diagnose and predict outcomes in Malawian children with febrile coma

  This study is looking at how brain wave patterns measured by EEG can help doctors tell the difference between coma caused by malaria and other reasons in children in Malawi, and whether these patterns can predict how well the kids will recover.

  NIH research Children's Research Institute · Washington, United States · NIH-10760235

Related topics

Quick answers

How many Coma clinical trials are recruiting right now?

10, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 6 countries. The most sites are in United States (4 trials), France (3 trials), Belgium (1 trial), Netherlands (1 trial), Spain (1 trial). Each study page lists its sites and which ones are recruiting.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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