Condition

Anxiety Depression clinical trials and research

• 19Clinical trials
• 3NIH research projects
• 12Countries

Newest Anxiety Depression clinical trials

All recruiting trials (19)

• Heartsight helps caregivers of kids after cardiac arrest manage uncertainty and fear

  This pilot trial tests if the Heartsight information program is acceptable and helpful for caregivers of children who recently had a cardiac arrest.

  Recruiting Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT07707037

• Attachment-Based Compassion Therapy to Prevent Burnout in Spanish Healthcare Professionals

  A compassion-based program is tested to see if it can help prevent burnout in Spanish doctors and nurses, compared with a relaxation program.

  Recruiting Hospital Miguel Servet · Zaragoza, Spain · NCT07698379

• Using a weighted blanket to help cancer patients during IV therapy

  A randomized study tests whether wearing a weighted blanket during IV cancer treatment reduces anxiety, stress, and depression and increases comfort compared with standard blankets.

  Recruiting Sultan Qaboos Comprehensive Cancer Center · Muscat, Seeb · NCT07653035

• Group-based ACT for psychological distress in young people

  Researchers are testing whether group-based ACT helps 16-25 year olds with depression or anxiety more than the usual individual therapy.

  Recruiting at 2 sites Sorlandet Hospital HF · Arendal, Agder and 1 other locations · NCT07617467

• Acupuncture vs Medication for Depression, Anxiety, and Sleep Issues in Chinese Adults

  This study tests whether acupuncture can be as effective or more cost-efficient and environmentally friendly than usual medication for reducing depression, anxiety, and sleep problems in adults 18–65 in China.

  Recruiting Phase 4 Duke Kunshan University · Kunshan, Jiangsu · NCT07552246

• Online group I-Reconstruction psychotherapy to reduce anxiety

  This trial tests whether a 10-week online group course using the I-Reconstruction method can help adults with anxiety feel less anxious.

  Recruiting International Association Psychosomatics And Health Therapy · Kyiv, Kyiv Oblast · NCT07397429

• Probiotics for Anxiety and Depression: Side by Side with an Antidepressant

  This study tests whether adding probiotics to treatment can help reduce anxiety and depression symptoms in adults compared with placebo, alongside traditional therapy, and checks safety and related biological markers.

  Recruiting Moon (Guangzhou) Biotechnology Co., Ltd. · Guangzhou, Guangdong · NCT07331987

• Fitness and mental health program for Latina cancer survivors

  See if combining stepped-care mental health counseling with an 8-week online exercise program helps Latina cancer survivors feel better mentally and physically.

  Recruiting Colorado State University · Fort Collins, Colorado · NCT07223346

• Big Five daily actions program adapted for Norway

  This trial will test whether a brief Norwegian program encouraging five daily actions helps people in Norway with mild-to-moderate anxiety or depression compared with a gratitude activity or no treatment.

  Recruiting Haukeland University Hospital · Bergen, Vestland and 1 other locations · NCT07151573

• Early exercise-based rehabilitation for adults hospitalized with acute pulmonary embolism

  This trial tries an early, supervised exercise and education program for adults hospitalized with acute pulmonary embolism to see if it prevents long-term breathlessness and improves quality of life.

  Recruiting at 6 sites Insel Gruppe AG, University Hospital Bern · Aarau and 5 other locations · NCT07143539

• Analyzing mental health treatment data from Greenbrook

  This study looks at past treatment data from Greenbrook to see how well different mental health treatments, like NeuroStar TMS and Esketamine, work for people with depression, OCD, and anxiety.

  Recruiting Neuronetics · Malvern, Pennsylvania · NCT06997549

• Analyzing patient data to understand TMS effects on depression and anxiety

  This study looks at real patient data to see how different factors affect the success of TMS therapy for people dealing with depression and anxiety.

  Recruiting Neuronetics · Malvern, Pennsylvania · NCT06917339

• Exposure therapy for anxiety in older adults

  This study is testing if exposure therapy from trained nurses can help older adults with anxiety feel better and improve their quality of life.

  Recruiting ProPersona · Nederland, Nijmegen · NCT06770517

• Online eCoaching to help family caregivers boost wellbeing and resilience

  This 6-week program will test whether an online self-help eCoaching course can reduce stress and depressive symptoms and increase confidence for family caregivers of older adults in Hong Kong.

  Recruiting The University of Hong Kong · Hong Kong · NCT06604481

• Metacognitive group therapy for autistic teens with anxiety and depression

  This project will try group metacognitive therapy to see if it helps 15–18-year-olds with autism who have anxiety and/or depression.

  Recruiting Uppsala University · Haninge, Stockholm County · NCT06441786

• Using RxWell to Reduce Opioid Use After Knee or Hip Surgery

  This study is testing whether a digital tool called RxWell can help people with mood disorders who are having knee or hip surgery reduce their opioid use and improve their mental health after the operation.

  Recruiting at 3 sites University of Pittsburgh · Monroeville, Pennsylvania and 2 other locations · NCT05658796

• Using pregnenolone to treat depression in people with HIV

  This study is testing if pregnenolone can help improve mood and brain function in people with HIV who are also dealing with depression.

  Recruiting Phase 2 Massachusetts General Hospital · Boston, Massachusetts · NCT05570812

• Investigating how CBT affects brain circuits in anxiety

  This study is trying to see how Cognitive Behavioural Therapy (CBT) changes brain activity in people with anxiety to help improve treatment options.

  Recruiting UCLH/UCL Joint Research Office · London · NCT05549102

• Evaluating factors related to chronic pain after hysterectomy

  This study is trying to find out what factors might lead to chronic pain after a hysterectomy in women, by looking at things like anxiety and how they feel about pain before and after the surgery.

  Recruiting KK Women's and Children's Hospital · Singapore · NCT04014829

NIH-funded research (3)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Environmental and psychological stressors shaping anxiety, depression, and alcohol-related health issues in people with HIV

  A patient-facing overview of how stress, mental health, and alcohol use interact with HIV to influence health and aging in people living with HIV.

  NIH research Lsu Health Sciences Center · New Orleans, United States · NIH-11416371

• The impact of green spaces on anxiety, depression, and ADHD in rural low-income children

  This study looks at how spending time in different types of parks and natural areas can help kids from rural, low-income families feel better and manage issues like anxiety, depression, and ADHD, with the goal of finding out what kinds of green spaces work best for their mental health.

  NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-11116311

• How media violence affects adolescent mental health and attention.

  This study looks at how watching media that shows gun violence affects the mental health of teenagers, especially their feelings of anxiety and depression, with a special focus on Black teens who might face extra stress; researchers will use brain scans to see how their brains react to this kind of media.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-11109708

Related topics

Quick answers

How many Anxiety Depression clinical trials are recruiting right now?

19, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 12 countries. The most sites are in United States (6 trials), Norway (2 trials), China (2 trials), Sweden (1 trial), Netherlands (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 1, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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