How common pain is in adults on mechanical ventilators in intensive care units

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective, multicenter cohort in Rio de Janeiro that will estimate the prevalence and intensity of pain in adult patients receiving invasive mechanical ventilation. Pain will be measured using behavioral and physiological indicators before and after procedures such as tracheal aspiration, and investigators will record sedation, analgesia use, and other clinical variables. The study will analyze how pain relates to outcomes including ventilator duration, delirium, infection rates, and length of hospital stay. Patients on neuromuscular blockers or with conditions that alter pain perception or behavioral responses will be excluded.

Why it matters

Who can join: the full rules

Inclusion Criteria

Participants of both sexes, aged 18 or over;

Participants who are using invasive mechanical ventilation,

Exclusion Criteria:

Participants undergoing treatment with neuromuscular blockers,;

Participants with any condition associated with altered pain perception (e.g., Guillain-Barré Syndrome, SCI, etc.);

Participants with any condition that would likely interfere with behavioral assessments of pain (e.g., decortication or decerebration posture)

As the assessments will be carried out before and after the tracheal aspiration procedure, if the patient does not have objective criteria for tracheal aspiration, he/she will be excluded from the study, irrefutably preventing the procedure from being carried out without express need.

Where it's running

• Hospital Central da Aeronáutica
  Rio de Janeiro, Rio de Janeiro, Brazil Recruiting
• Hospital Central da Polícia Militar do Estado do Rio de Janeiro
  Rio de Janeiro, Rio de Janeiro, Brazil Recruiting
• Hospital Universitário Clementino Fraga Filho
  Rio de Janeiro, Rio de Janeiro, Brazil Recruiting
• Hospital Universitário Gafrée Guinle
  Rio de Janeiro, Rio de Janeiro, Brazil Recruiting

Study contacts

• Study coordinator: Arthur S Ferreira, Dsc
• Email: asferreira@unisuam.edu.br
• Phone: +552238829797

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.