Comparing VC and PC ventilation effects during laparoscopic gynecologic surgery
Official title: The Effects of Volume-controlled Ventilation Versus Pressure-controlled Ventilation on Cerebral and Respiratory Parameters in Patients Undergoing Laparoscopic Gynecologic Surgery
Run by Umraniye Education and Research Hospital · NCT06482983 · Data updated 2026-11-12
This study is testing whether using volume control or pressure control ventilation during laparoscopic gynecologic surgery can improve breathing and recovery for patients.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 70 Years |
| Sex | Women only |
| Enrollment | 120 (estimated) |
| Sponsor | Umraniye Education and Research Hospital Government |
| Locations | 1 site (Istanbul, Umraniye) |
| Status | Recruiting |
| Started | May 1, 2023 |
| Main results expected | September 30, 2024 |
| Study ends | July 31, 2026 |
| Registry record updated | November 19, 2025 |
| Trial ID | NCT06482983 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults aged 18 to 70 with an ASA classification of 1 to 3 undergoing laparoscopic gynecologic surgery.
✕Probably not a fit
Patients with severe chronic respiratory conditions, significant obesity, or those outside the age range may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates the impact of two different mechanical ventilation modes, volume control (VC) and pressure control (PC), on respiratory and cerebral parameters in patients undergoing laparoscopic gynecologic surgery. The research focuses on patients positioned in Trendelenburg with CO2 insufflation, assessing how these factors influence postoperative complications such as atelectasis and hemodynamic stability. By analyzing the effects of these ventilation strategies, the study aims to enhance patient safety and outcomes during surgery.
Why it matters
Potential benefit: If successful, this study could lead to improved ventilation strategies that minimize respiratory complications during laparoscopic surgeries.
How similar studies have gone: While the specific comparison of VC versus PC ventilation in this context may be novel, similar studies have indicated the importance of ventilation strategies in minimizing surgical complications.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * 18-70 age * ASA 1-3 Exclusion Criteria: * Under 18 years of age, over 70 years of age, * ASA IV, * history of severe chronic obstructive pulmonary disease (COPD, GOLD III or IV) ,-history of severe or uncontrolled bronchial asthma, presence of restrictive lung disease, * history of any thoracic surgery operation, need for thoracic drainage before surgery * patients receiving preoperative renal replacement therapy, * congestive heart failure (NYHA grade III or IV), * extremely obese (body Mass Index, BMI \> 35 Kg/m2) * patients without patient consent
Where it's running
-
Umraniye research and education hospital
Istanbul, Umraniye, Turkey (Türkiye) Recruiting
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.