Comparing VC and PC ventilation effects during laparoscopic gynecologic surgery
The Effects of Volume-controlled Ventilation Versus Pressure-controlled Ventilation on Cerebral and Respiratory Parameters in Patients Undergoing Laparoscopic Gynecologic Surgery
This study is testing whether using volume control or pressure control ventilation during laparoscopic gynecologic surgery can improve breathing and recovery for patients.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 120 (estimated) |
| Ages | 18 Years to 70 Years |
| Sex | Female |
| Sponsor | Umraniye Education and Research Hospital Government |
| Locations | 1 site (Istanbul, Umraniye) |
| Trial ID | NCT06482983 on ClinicalTrials.gov |
What this trial studies
This study investigates the impact of two different mechanical ventilation modes, volume control (VC) and pressure control (PC), on respiratory and cerebral parameters in patients undergoing laparoscopic gynecologic surgery. The research focuses on patients positioned in Trendelenburg with CO2 insufflation, assessing how these factors influence postoperative complications such as atelectasis and hemodynamic stability. By analyzing the effects of these ventilation strategies, the study aims to enhance patient safety and outcomes during surgery.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 to 70 with an ASA classification of 1 to 3 undergoing laparoscopic gynecologic surgery.
Not a fit: Patients with severe chronic respiratory conditions, significant obesity, or those outside the age range may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved ventilation strategies that minimize respiratory complications during laparoscopic surgeries.
How similar studies have performed: While the specific comparison of VC versus PC ventilation in this context may be novel, similar studies have indicated the importance of ventilation strategies in minimizing surgical complications.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * 18-70 age * ASA 1-3 Exclusion Criteria: * Under 18 years of age, over 70 years of age, * ASA IV, * history of severe chronic obstructive pulmonary disease (COPD, GOLD III or IV) ,-history of severe or uncontrolled bronchial asthma, presence of restrictive lung disease, * history of any thoracic surgery operation, need for thoracic drainage before surgery * patients receiving preoperative renal replacement therapy, * congestive heart failure (NYHA grade III or IV), * extremely obese (body Mass Index, BMI \> 35 Kg/m2) * patients without patient consent
Where this trial is running
Istanbul, Umraniye
- Umraniye research and education hospital — Istanbul, Umraniye, Turkey (Türkiye) (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.