Using EEG to guide sedation and pain relief in ICU patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the use of the Conox® system, which analyzes EEG data to guide sedation and analgesia in ICU patients requiring mechanical ventilation. The goal is to optimize sedation levels to reduce complications associated with excessive sedation, such as prolonged mechanical ventilation and increased risk of infections. Patients will be monitored using this device to ensure their sedation is tailored to their specific needs, compared to standard care practices. The study aims to improve patient outcomes in critical care settings.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Age 18-90 years Admission to the ICU for less than 24 hours Expected mechanical ventilation for \>48 hours Ongoing sedation

Exclusion Criteria:

Mechanical ventilation (MV) for less than 48 hours Patient or next of kin refusal to participate BMI \> 35 Cerebrovascular disease Scheduled surgery Neuromuscular disease Presence of craniofacial trauma that prevents the placement of electrodes

Where it's running

• Azienda Ospedaliera Universitaria Sant'Anna
  Ferrara, Italy, Italy Recruiting
• Azienda Ospedaliera Universitaria Federico II - "Policlinico"
  Naples, Napoli, Italy Not yet recruiting

Study contacts

• Study coordinator: Gaetano Scaramuzzo, MD
• Email: scrgtn@unife.it
• Phone: 0532239158

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.