Evaluating ventilation practices in children during general anesthesia

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to assess the current practices of mechanical ventilation in children undergoing general anesthesia, focusing on the incidence of postoperative pulmonary complications (PPCs). It will gather data from multiple international centers to describe ventilatory support practices and identify factors associated with PPCs, hospital length of stay, and pediatric intensive care unit (PICU) admissions. The study will also explore geo-economic variations in these practices and develop a risk score for PPCs similar to the ARISCAT score.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* aged ≤ 16 years;
* undergoing general anesthesia
* airway management with tube or LMA; and
* connected to mechanical ventilator . minimum duration of procedure: 15 minutes

Exclusion Criteria:

* patients undergoing surgical procedures involving extra-corporal circulation;
* patients receiving ventilation with high frequency jet ventilation or high frequency oscillatory ventilation;
* sedation without airway management in the form of a endotracheal tube or a supraglottic airway device; and
* (rigid) bronchoscopic procedures with maintenance of spontaneous ventilation.

Where it's running

• Amsterdam University Medical Centers
  Amsterdam, Please Select, Netherlands Recruiting
• Perth Children's Hospital
  Perth, Australia Not yet recruiting
• IRCCS Istituto Giannina Gaslini
  Genoa, Italy Not yet recruiting
• Universitatsspital Bern
  Bern, Switzerland Not yet recruiting

Study contacts

• Principal investigator: Marcus Schultz, Prof — Amsterdam UMC
• Study coordinator: Jorinde Polderman, MD, PhD
• Email: j.a.polderman@amsterdamumc.nl
• Phone: +31205669111

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.