Condition
Lung Cancer (Diagnosis) clinical trials and research
As of November 12, 2026, Find a Trial lists 38 Lung Cancer (Diagnosis) clinical trials that are recruiting, at sites in 16 countries (most in United States (10), China (9), Denmark (4)). By phase: Phase 4 (1), Phase 1/2 (1), Phase 3 (1). The most active sponsors are Vejle Hospital (2), Taipei Medical University (2), University of Rochester (2). There are also 3 NIH-funded research projects on Lung Cancer (Diagnosis), with $447,044 in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 38Clinical trials
- 3NIH research projects
- 16Countries
Newest Lung Cancer (Diagnosis) clinical trials
All recruiting trials (38)
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Risk-based lung cancer screening in COPD patients using ML and clinical models
This study tests whether a PLCOm2012 risk model plus a machine learning model can spot COPD patients at high risk for lung cancer to see if they benefit from low-dose CT screening.
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AI-Personalized Discharge Education After Lung Cancer Surgery
This study tests whether an AI-generated, personalized discharge guide helps patients recover better after lung cancer surgery compared with standard discharge education.
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Next Generation Delivery System (NGDS) for SBRT in thorax and upper abdomen
A study tests a new machine to deliver SBRT more quickly and comfortably for adults with thoracic or upper abdominal cancers.
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Low-Intensity Endurance Exercise to Help Lung Cancer-Related Fatigue
This trial tests whether light, regular endurance exercise can help reduce fatigue and improve quality of life for people with lung cancer in addition to their usual care.
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Low-Intensity Endurance Exercise for Lung Cancer-Related Fatigue
A randomized trial tests whether light, regular endurance exercise can help reduce fatigue and improve quality of life for people with lung cancer.
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Comparing CT-guided Lung Biopsy vs Shape-Sensing Robotic Bronchoscopy for Small Nodules
This trial tests whether shape-sensing robotic-assisted bronchoscopy with cone-beam CT can diagnose small lung nodules as well as the standard CT-guided lung biopsy, with a focus on safety.
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Nitride-based Raman biochip for lung cancer diagnosis and monitoring
A large observational study in Taiwan will test whether a blood-based nitride-based Raman biochip can help diagnose lung cancer and monitor patients over time.
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Clonal Hematopoiesis Effects with Chemo and Radiation in Solid Cancers
This study tests whether clonal hematopoiesis affects outcomes for adults with solid cancers who are receiving chemotherapy or radiation.
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Registry of Minimally Invasive Cancer Treatments Using Spectral Angio-CT Guidance
This registry collects data from adults undergoing image-guided, minimally invasive cancer treatments to see if spectral angio-CT guidance helps predict outcomes and improve planning.
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Blood biomarkers to help tell if a lung nodule is cancer or not
A blood test-based approach is being tested to see if biomarkers can help determine whether a detected lung nodule is malignant or benign in patients referred for further evaluation.
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Promoting Radon Testing Among Mothers of Young Children
This study tests a smartphone radon app to help mothers of kids 4 and under decide to test their home for radon using a free test kit.
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Blood test and AI to find people with COPD at higher risk of lung cancer
This project will see if a blood test combined with an AI model can identify people with COPD who are at higher risk of lung cancer so they can be referred for a low‑dose CT scan.
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Enhanced COPD care for people being checked for lung cancer
This project will test whether finding and treating COPD early in people being checked for possible lung cancer helps symptoms, lung function, and overall care.
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Tislelizumab treatment for people with lung cancer in routine care
We will see how tislelizumab is used and how patients with resectable, locally advanced, or extensive-stage lung cancer do when treated in everyday clinical care in Germany and Austria.
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Using a blood telomere test to help diagnose lung cancer
This research will test whether a blood telomere test can tell who has lung cancer among adults 45 and older by comparing newly diagnosed, untreated patients to high‑ and low‑risk controls.
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Predicting blood clots after lung cancer surgery
This project will try to use clinical, surgical, and lab data to predict which adults having lung cancer surgery may develop blood clots after the operation.
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Measuring airway inflammation markers in breath to help detect lung conditions
This project tests whether a breath test called Inflammacheck® that measures hydrogen peroxide and other inflammation markers can quickly triage adults with suspected or confirmed lung cancer and other respiratory conditions.
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Distinguishing N2a from N2b lymph node spread during EBUS-TBNA and whether changing the needle helps
It will see if changing the EBUS-TBNA needle between lymph nodes helps doctors tell apart N2a from N2b in people having mediastinal staging for suspected or confirmed lung cancer.
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EBNK-001 allogeneic NK cell therapy with low-dose IL-15, with or without pembrolizumab, for advanced solid tumors
This treatment tests an off-the-shelf NK cell product (EBNK-001) given with low-dose IL-15, either alone or with pembrolizumab, in adults with advanced or metastatic solid tumors who have exhausted standard options.
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Blood test using cfDNA fragment patterns to tell if a lung nodule is cancer
This project will see if a blood test that analyzes cfDNA fragments can tell adults with CT-detected lung nodules whether the nodules are benign or malignant.
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Apneic oxygenation for the non-ventilated lung during lung cancer surgery.
This test will see if giving oxygen to the non-ventilated lung during one-lung ventilation reduces inflammation and helps recovery in adults having lung cancer surgery.
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Immune cells in lung disease and how they could guide immunotherapy
This project sees if immune cell profiling from blood can explain why people with lung cancer, sarcoidosis, or COPD respond differently to immunotherapy or develop chronic lung inflammation.
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Molecular profiling of primary lung cancer and its metastatic site
This project will compare the DNA of a person’s primary non-small cell lung tumor and a matching metastatic lesion using next-generation sequencing to see if they differ.
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Acupressure for Cough in Lung Cancer Survivors
This trial tests whether self-administered acupressure can lessen cough and related symptoms in people who have survived lung cancer.
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Functional Lung-Sparing Planning Guided by Lung Perfusion PET/CT vs. Anatomy for Lung SBRT
We test whether planning lung SBRT with functional lung information from a PET/CT scan can spare healthy lung tissue and reduce side effects for adult patients with primary or metastatic lung tumors.
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Boosting lung cancer screening for patients seen in the emergency department
This project will test whether giving eligible emergency department patients a facilitated referral plus text reminders helps more people get lung cancer screening.
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Boosting lung cancer screening for patients seen in the emergency department
This project will test whether giving eligible emergency department patients a facilitated referral plus text reminders helps more people get lung cancer screening.
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Comparing three transthoracic needle biopsy techniques for people with suspected lung cancer
This project will test three transthoracic needle aspiration methods to see which one yields the best tumor samples in adults with suspected lung cancer.
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Antrodia cinnamomea supplement to improve quality of life during chemotherapy for lung cancer
This trial will test whether taking a daily Antrodia cinnamomea-containing capsule helps people with lung cancer on platinum chemotherapy feel better by reducing nausea, improving sleep, and easing cancer-related symptoms.
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High-throughput tissue processing for clearer 3D images of lung and colorectal cancers
This project tests a high-throughput tissue-processing and 3D imaging approach to create more detailed tumor images from people with lung or colorectal cancer.
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Preventive lung, breast, and prostate cancer screening at community resource spots
This program tries community outreach at resource centers to help underserved adults get screening, follow-up diagnosis, and treatment for lung, breast, and prostate cancers.
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Using a paravertebral block during thoracic (VATS/RATS) surgery to reduce postoperative complications
This study will try an intraoperative paravertebral block to see if it lowers postoperative complications in adults having VATS or RATS for lung or mediastinal procedures.
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FlowPath Lung sputum test to detect cancer in people with 6–30 mm lung nodules
This test will try to detect lung cancer from a sputum sample using the FlowPath Lung assay in high‑risk people aged 50–80 who have a 6–30 mm lung nodule found on CT.
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Telehealth collaborative care program for lung cancer-related anxiety and depression
This project tests whether a more intensive 'high-touch' outreach approach gets more people with lung cancer who have anxiety or depression to join a telehealth collaborative care program than standard outreach.
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AI and CT-based prediction of immunotherapy response in lung cancer patients
This project will try to use CT scans and artificial intelligence to predict whether adults with lung cancer will respond to immunotherapy.
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Multi-omics testing to distinguish benign from malignant lung nodules
This project will test whether combining blood single-cell data, flow cytometry, and CT image features can tell if a pulmonary nodule is benign or cancerous in people scheduled for nodule surgery.
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Evaluating a Virtual Oncology Program for Veterans with Cancer
This study is testing a virtual cancer care program for veterans to see if it helps them get better treatment and support for lung, colorectal, prostate, and breast cancers.
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Validation of a blood test for early lung cancer detection
This study is testing a new blood test to see if it can help detect lung cancer early in people who are at high risk.
NIH-funded research (3)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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Plasma microRNA clues to tell cancer from non-cancer in lung nodules
A blood test is being developed to help tell whether lung nodules found on CT scans are cancer or not, aiming to spare patients unnecessary procedures.
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Improving the diagnosis of lung cancer by analyzing patient experiences and healthcare systems.
This study is looking into the challenges people face when getting diagnosed with lung cancer, aiming to find ways to speed up the process and improve outcomes for patients like you.
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Improving lung cancer diagnosis with advanced bronchoscopy techniques
This study is looking at how to make bronchoscopy, a test for lung cancer, more accurate by using smart computer technology to help doctors find lung problems better, which could lead to earlier and more effective treatment for patients like you.
Related topics
Quick answers
How many Lung Cancer (Diagnosis) clinical trials are recruiting right now?
38, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 16 countries. The most sites are in United States (10 trials), China (9 trials), Denmark (4 trials), Taiwan (4 trials), Germany (2 trials). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 4: 1, Phase 1/2: 1, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.