Low-Intensity Endurance Exercise to Help Lung Cancer-Related Fatigue
Official title: The Effects of Low Intensity Endurance Exercise on Improving Mitochondrial Function, Cell Bioelectrical Impedance Phase Angle, Fatigue and Quality of Life in Lung Cancer Patients With Cancer-related Fatigue
Run by Taipei Medical University · NCT07806682 · Data updated 2026-11-12
This trial tests whether light, regular endurance exercise can help reduce fatigue and improve quality of life for people with lung cancer in addition to their usual care.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 20 Years to 70 Years |
| Sex | All |
| Enrollment | 150 (estimated) |
| Sponsor | Taipei Medical University Academic / other |
| Locations | 1 site (Taipei) |
| Status | Recruiting |
| Started | March 10, 2025 |
| Main results expected | July 31, 2027 |
| Study ends | July 31, 2027 |
| Registry record updated | September 8, 2026 |
| Trial ID | NCT07806682 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 20–70 with a lung cancer diagnosis who are medically cleared for exercise and can communicate in Mandarin, Taiwanese, or Hakka.
✕Probably not a fit
Patients who cannot safely participate in any exercise or who do not respond to the intervention may see no fatigue improvement.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
In this randomized trial, adults with lung cancer and cancer-related fatigue are assigned to either no exercise, or low-intensity endurance training (continuous or interval) for 12 weeks to see if it improves mitochondrial function, body composition, fatigue, and quality of life. The study measures mitochondrial DNA content, mitochondrial function markers, bioelectrical impedance phase angle, fatigue levels, and quality of life. Participants exercise about 30 minutes per day, 5 days a week, at light to very light effort levels, with warm-up and cool-down. The trial is conducted at Taipei Medical University and led by the institution with no additional collaborating sites listed.
Why it matters
Potential benefit: If successful, patients may experience less fatigue and better quality of life through a feasible, low-intensity exercise program.
How similar studies have gone: Prior research suggests exercise can benefit fatigue in cancer patients, but the specific low-intensity, mitochondrial-focused approach in lung cancer is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Patients who are diagnosed with lung cancer by a physician ; 2. Patients aged 20-70 years; 3. Patients who are determined by a physician, after assessment of their physical condition, to be suitable for exercise; 4. Patients who have graduated from elementary school or above. Exclusion Criteria: 1. Patients who are unable to communicate in Mandarin, Taiwanese, or Hakka; 2. Patients who are determined by a physician to be physically unsuitable for performing any exercise.
Where it's running
-
Taipei Medical University
Taipei, Taiwan Recruiting
Study contacts
- Study coordinator: Hsiu Ting Tsai, PhD
- Email: hsiuting@tmu.edu.tw
- Phone: 886227361661
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.