Clinical trial Recruiting at 1 site Interventional Ages 20 to 70

Low-Intensity Endurance Exercise to Help Lung Cancer-Related Fatigue

Official title: The Effects of Low Intensity Endurance Exercise on Improving Mitochondrial Function, Cell Bioelectrical Impedance Phase Angle, Fatigue and Quality of Life in Lung Cancer Patients With Cancer-related Fatigue

Run by Taipei Medical University · NCT07806682 · Data updated 2026-11-12

This trial tests whether light, regular endurance exercise can help reduce fatigue and improve quality of life for people with lung cancer in addition to their usual care.

Quick facts

Study typeInterventional
Ages20 Years to 70 Years
SexAll
Enrollment150 (estimated)
SponsorTaipei Medical University
Academic / other
Locations1 site (Taipei)
StatusRecruiting
StartedMarch 10, 2025
Main results expectedJuly 31, 2027
Study endsJuly 31, 2027
Registry record updatedSeptember 8, 2026
Trial IDNCT07806682 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 20–70 with a lung cancer diagnosis who are medically cleared for exercise and can communicate in Mandarin, Taiwanese, or Hakka.

Probably not a fit

Patients who cannot safely participate in any exercise or who do not respond to the intervention may see no fatigue improvement.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

In this randomized trial, adults with lung cancer and cancer-related fatigue are assigned to either no exercise, or low-intensity endurance training (continuous or interval) for 12 weeks to see if it improves mitochondrial function, body composition, fatigue, and quality of life. The study measures mitochondrial DNA content, mitochondrial function markers, bioelectrical impedance phase angle, fatigue levels, and quality of life. Participants exercise about 30 minutes per day, 5 days a week, at light to very light effort levels, with warm-up and cool-down. The trial is conducted at Taipei Medical University and led by the institution with no additional collaborating sites listed.

Why it matters

Potential benefit: If successful, patients may experience less fatigue and better quality of life through a feasible, low-intensity exercise program.

How similar studies have gone: Prior research suggests exercise can benefit fatigue in cancer patients, but the specific low-intensity, mitochondrial-focused approach in lung cancer is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Patients who are diagnosed with lung cancer by a physician ;
2. Patients aged 20-70 years;
3. Patients who are determined by a physician, after assessment of their physical condition, to be suitable for exercise;
4. Patients who have graduated from elementary school or above.

Exclusion Criteria:

1. Patients who are unable to communicate in Mandarin, Taiwanese, or Hakka;
2. Patients who are determined by a physician to be physically unsuitable for performing any exercise.

Where it's running

  • Taipei Medical University
    Taipei, Taiwan
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.