Validation of a blood test for early lung cancer detection

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The PROACT LUNG study is a prospective multi-center observational study aimed at validating the Freenome Multiomics Blood Test for early lung cancer detection. Participants who are at high risk will provide blood samples while undergoing routine low-dose computed tomography (LDCT) screening. The study will collect demographic and clinical data, including medical history and exposure factors, to evaluate the test's performance. Participants will be followed for a minimum of 24 months to assess outcomes related to lung cancer diagnosis.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Age 50 years or older within 30 days of enrollment
2. Current or former smokers with a cumulative smoking history of ≥ 20 pack-year
3. Able to comprehend and willing to sign and date the informed consent and HIPAA authorization documents

Exclusion Criteria:

1. Any active therapy for cancer, including but not limited to surgery, chemotherapy, biologic therapy, immunotherapy, and/or radiation therapy at the time of enrollment
2. History of any malignancy within prior 5 years of enrollment (except for non- melanoma skin cancer)
3. History of organ, tissue, and bone marrow transplantation
4. Screened for lung cancer or having chest CT scan 12 months before enrollment
5. Having signs and symptoms of lung cancer such as hemoptysis, superior vena cava syndrome, Cushing syndrome, and Pancoast syndrome
6. Received a blood transfusion in the 30 days preceding enrollment
7. Known to be pregnant
8. Participated or currently participating in another Freenome-sponsored clinical study
9. Participated or currently participating in a clinical research study in which an experimental medication has been administered during the 60 days preceding enrollment
10. Any condition that in the opinion of the Investigator should not be enrolled in the study

Where it's running

• Science 37
  Los Angeles, California, United States Recruiting
• Stamford Hospital
  Stamford, Connecticut, United States Recruiting
• Hillcrest Medical Research
  DeLand, Florida, United States Recruiting
• Universal Axon Clinical Research
  Doral, Florida, United States Recruiting
• I.H.S Health, LLC
  Kissimmee, Florida, United States Recruiting
• United Medical Research
  Port Orange, Florida, United States Recruiting

Study contacts

• Study coordinator: Harris Naemi, BS
• Email: FRNM007@freenome.com
• Phone: 925-322-6486

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.