Antrodia cinnamomea supplement to improve quality of life during chemotherapy for lung cancer

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Adults with pathologically or radiographically confirmed lung cancer who are receiving platinum-based chemotherapy at Tri-Service General Hospital will be randomly assigned in a double-blind manner to receive either a capsule containing Antrodia cinnamomea plus turmeric and probiotics or a capsule with turmeric and probiotics only. Participants will take the assigned capsules daily for three months with continued follow-up for a total of six months (24 weeks). Researchers will use validated questionnaires to measure nausea and vomiting, sleep quality, overall quality of life, and other cancer-related symptoms and will compare outcomes between the two groups. The trial is conducted at Tri-Service General Hospital in Taipei and is sponsored by that hospital with collaboration from Balay Biotechnology Corporation.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Pathologically and radio-graphically diagnosed lung cancer
* Age greater than 18 years
* Received platinum-based chemotherapy
* Life expectancy of six months or longer

Exclusion Criteria:

* Inability to comply with timely supplementation administration.
* Within 14 days prior to trial entry, laboratory data showing abnormal liver function, abnormal kidney function
* Within 30 days prior to trial entry, unexplained fever ≥38.5°C for 7 consecutive days or chronic diarrhea for 15 consecutive days.
* Currently receiving hormone therapy.
* Major cardiac disease or arrhythmia severe enough that the attending physician considers the patient unsuitable for trial participation.
* Major neuropathy.
* Patients with currently active acute infections.
* Patients with known allergies/allergic reactions to the investigational product or any components in their formulations.
* Patients currently taking supplements containing Antrodia camphorata extract.

Where it's running

• Tri-Service General Hospital
  Taipei, Taiwan Recruiting

Study contacts

• Study coordinator: Chen-Liang Tsai
• Email: doc10376@gmail.com
• Phone: 886-2-8792-3311

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.