Low-Intensity Endurance Exercise for Lung Cancer-Related Fatigue
Official title: The Effects of Low-Intensity Endurance Exercise on Improving Fatigue, Sleep, Quality of Life, Mitochondrial Function, Cellular Bioelectrical Impedance Phase Angle, and Predictors of Exercise Adherence in Patients With Lung Cancer
Run by Taipei Medical University · NCT07795580 · Data updated 2026-11-12
A randomized trial tests whether light, regular endurance exercise can help reduce fatigue and improve quality of life for people with lung cancer.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 20 Years and up |
| Sex | All |
| Enrollment | 450 (estimated) |
| Sponsor | Taipei Medical University Academic / other |
| Locations | 1 site (Taipei) |
| Status | Recruiting |
| Started | July 1, 2026 |
| Main results expected | July 2028 |
| Study ends | July 2029 |
| Registry record updated | August 31, 2026 |
| Trial ID | NCT07795580 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults with lung cancer and cancer-related fatigue who can communicate in Mandarin Chinese, Taiwanese, or Hakka and are medically suitable for light-to-moderate exercise.
✕Probably not a fit
Patients who cannot safely perform even light exercise or who do not experience fatigue related to cancer may not derive benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This randomized controlled trial will assign lung cancer patients with cancer-related fatigue to three groups: a non-exercise control, a 30-minute daily low-intensity continuous endurance program, or a 30-minute daily low-intensity interval endurance program, five days a week. The study will measure outcomes such as fatigue, quality of life, mitochondrial function markers, and body composition, to see if exercise can influence cellular and bioelectrical parameters related to fatigue. Participants will be adults 20 and older, recruited in Taipei, with exercise sessions supervised to maintain prescribed heart-rate targets. The trial tests whether physiological changes mediate improvement in fatigue and whether personality traits relate to adherence.
Why it matters
Potential benefit: If successful, participants could experience less fatigue and better quality of life, with potential improvements in mitochondrial health.
How similar studies have gone: Previous research suggests exercise can improve fatigue in cancer patients, but this specific low-intensity, modality-structured approach in lung cancer is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Individuals diagnosed with lung cancer by a physician. 2. Aged 20 years or older. 3. Education level of elementary school graduation or above. Exclusion Criteria: 1. Individuals who are unable to communicate in Mandarin Chinese, Taiwanese, or Hakka. 2. Individuals whose physical condition is determined by a physician to be unsuitable for performing any exercise.
Where it's running
-
Taipei Medical University
Taipei, Taiwan Recruiting
Study contacts
- Study coordinator: Hsiu Ting Tsai, PhD
- Email: hsiuting@tmu.edu.tw
- Phone: 886227361661
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.