Clinical trial Recruiting at 1 site Interventional Ages 20 and up

Low-Intensity Endurance Exercise for Lung Cancer-Related Fatigue

Official title: The Effects of Low-Intensity Endurance Exercise on Improving Fatigue, Sleep, Quality of Life, Mitochondrial Function, Cellular Bioelectrical Impedance Phase Angle, and Predictors of Exercise Adherence in Patients With Lung Cancer

Run by Taipei Medical University · NCT07795580 · Data updated 2026-11-12

A randomized trial tests whether light, regular endurance exercise can help reduce fatigue and improve quality of life for people with lung cancer.

Quick facts

Study typeInterventional
Ages20 Years and up
SexAll
Enrollment450 (estimated)
SponsorTaipei Medical University
Academic / other
Locations1 site (Taipei)
StatusRecruiting
StartedJuly 1, 2026
Main results expectedJuly 2028
Study endsJuly 2029
Registry record updatedAugust 31, 2026
Trial IDNCT07795580 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults with lung cancer and cancer-related fatigue who can communicate in Mandarin Chinese, Taiwanese, or Hakka and are medically suitable for light-to-moderate exercise.

Probably not a fit

Patients who cannot safely perform even light exercise or who do not experience fatigue related to cancer may not derive benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized controlled trial will assign lung cancer patients with cancer-related fatigue to three groups: a non-exercise control, a 30-minute daily low-intensity continuous endurance program, or a 30-minute daily low-intensity interval endurance program, five days a week. The study will measure outcomes such as fatigue, quality of life, mitochondrial function markers, and body composition, to see if exercise can influence cellular and bioelectrical parameters related to fatigue. Participants will be adults 20 and older, recruited in Taipei, with exercise sessions supervised to maintain prescribed heart-rate targets. The trial tests whether physiological changes mediate improvement in fatigue and whether personality traits relate to adherence.

Why it matters

Potential benefit: If successful, participants could experience less fatigue and better quality of life, with potential improvements in mitochondrial health.

How similar studies have gone: Previous research suggests exercise can improve fatigue in cancer patients, but this specific low-intensity, modality-structured approach in lung cancer is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Individuals diagnosed with lung cancer by a physician.
2. Aged 20 years or older.
3. Education level of elementary school graduation or above.

Exclusion Criteria:

1. Individuals who are unable to communicate in Mandarin Chinese, Taiwanese, or Hakka.
2. Individuals whose physical condition is determined by a physician to be unsuitable for performing any exercise.

Where it's running

  • Taipei Medical University
    Taipei, Taiwan
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.