Enhanced COPD care for people being checked for lung cancer
Enhanced COPD Management in Suspected Lung Cancer Patients - Improving Outcomes Through Timely Intervention
This project will test whether finding and treating COPD early in people being checked for possible lung cancer helps symptoms, lung function, and overall care.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 280 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Region of Southern Denmark Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Vejle) |
| Trial ID | NCT07543601 on ClinicalTrials.gov |
What this trial studies
This open-label randomized controlled trial at the Lung Cancer Investigation Unit, Lillebaelt Hospital Vejle, compares tailored COPD consultations and early optimal COPD treatment to usual care in patients undergoing diagnostic evaluation for suspected lung cancer. Eligible participants must have spirometry-confirmed obstructive airflow limitation at the first outpatient visit and will receive personalized inhaler optimization, smoking-cessation support, and structured follow-up based on COPD severity. The trial will measure changes in health status and lung function as primary outcomes, with secondary outcomes including healthcare utilization, completion of the diagnostic pathway, and survival-related metrics. Clinical, functional, and health-economic data will be combined to determine whether integrated COPD management improves outcomes during the lung cancer diagnostic process.
Who should consider this trial
Good fit: Ideal candidates are adults undergoing diagnostic evaluation for suspected lung cancer who have spirometry-confirmed obstructive airflow limitation at the first outpatient visit.
Not a fit: Patients without obstructive spirometry, those with significant comorbidities that interfere with spirometry or diagnostic procedures, pregnant or breastfeeding women, and patients already receiving optimal COPD care are less likely to benefit.
Why it matters
Potential benefit: If successful, this approach could improve symptoms and lung function, reduce hospital visits and costs, and possibly improve survival for patients evaluated for lung cancer.
How similar studies have performed: Integrated COPD management has improved outcomes in general COPD populations, but randomized evidence specifically targeting patients during lung cancer diagnostic work-ups is limited.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Undergoing diagnostic evaluation for suspected lung cancer * Spirometry showing obstructive airflow limitation (FEV₁/FVC \< 75 % or FEV₁ \< 80 %, and no reversibility) at the first outpatient visit at the lung cancer evaluation Exclusion Criteria: * Presence of significant comorbidities that may interfere with diagnostic procedures or spirometry * Pregnant or breastfeeding women
Where this trial is running
Vejle
- Lung Cancer Investigation Unit, Lillebaelt Hospital Vejle — Vejle, Denmark (Recruiting)
Study contacts
- Study coordinator: Ditte Krag-Hansen, MD, PhD student
- Email: ditte.krag-hansen@rsyd.dk
- Phone: +45 7940 5720
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.