Enhanced COPD care for people being checked for lung cancer
Official title: Enhanced COPD Management in Suspected Lung Cancer Patients - Improving Outcomes Through Timely Intervention
Run by Region of Southern Denmark · NCT07543601 · Data updated 2026-11-12
This project will test whether finding and treating COPD early in people being checked for possible lung cancer helps symptoms, lung function, and overall care.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 280 (estimated) |
| Sponsor | Region of Southern Denmark Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Vejle) |
| Status | Recruiting |
| Started | March 6, 2026 |
| Main results expected | June 30, 2027 |
| Study ends | June 30, 2027 |
| Registry record updated | April 22, 2026 |
| Trial ID | NCT07543601 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults undergoing diagnostic evaluation for suspected lung cancer who have spirometry-confirmed obstructive airflow limitation at the first outpatient visit.
✕Probably not a fit
Patients without obstructive spirometry, those with significant comorbidities that interfere with spirometry or diagnostic procedures, pregnant or breastfeeding women, and patients already receiving optimal COPD care are less likely to benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This open-label randomized controlled trial at the Lung Cancer Investigation Unit, Lillebaelt Hospital Vejle, compares tailored COPD consultations and early optimal COPD treatment to usual care in patients undergoing diagnostic evaluation for suspected lung cancer. Eligible participants must have spirometry-confirmed obstructive airflow limitation at the first outpatient visit and will receive personalized inhaler optimization, smoking-cessation support, and structured follow-up based on COPD severity. The trial will measure changes in health status and lung function as primary outcomes, with secondary outcomes including healthcare utilization, completion of the diagnostic pathway, and survival-related metrics. Clinical, functional, and health-economic data will be combined to determine whether integrated COPD management improves outcomes during the lung cancer diagnostic process.
Why it matters
Potential benefit: If successful, this approach could improve symptoms and lung function, reduce hospital visits and costs, and possibly improve survival for patients evaluated for lung cancer.
How similar studies have gone: Integrated COPD management has improved outcomes in general COPD populations, but randomized evidence specifically targeting patients during lung cancer diagnostic work-ups is limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Undergoing diagnostic evaluation for suspected lung cancer * Spirometry showing obstructive airflow limitation (FEV₁/FVC \< 75 % or FEV₁ \< 80 %, and no reversibility) at the first outpatient visit at the lung cancer evaluation Exclusion Criteria: * Presence of significant comorbidities that may interfere with diagnostic procedures or spirometry * Pregnant or breastfeeding women
Where it's running
-
Lung Cancer Investigation Unit, Lillebaelt Hospital Vejle
Vejle, Denmark Recruiting
Study contacts
- Study coordinator: Ditte Krag-Hansen, MD, PhD student
- Email: ditte.krag-hansen@rsyd.dk
- Phone: +45 7940 5720
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.