Condition

Intracranial Aneurysm clinical trials and research

• 24Clinical trials
• 17NIH research projects
• 43Countries

Newest Intracranial Aneurysm clinical trials

All recruiting trials (24)

• Flow Diverter Stent for Intracranial Aneurysm in China

  This study tests a novel flow diverter stent to treat intracranial aneurysms in adults and follows patients through treatment and follow-up.

  Recruiting Beijing Tiantan Hospital · Beijing, Beijing Municipality · NCT07821957

• Real-World Experience With the WEB Device for Intracranial Aneurysms

  This study tests how well the Woven EndoBridge device works in routine treatment of intracranial aneurysms in China across multiple centers.

  Recruiting Xuanwu Hospital, Beijing · Beijing · NCT07620626

• Choydar flow-directed mesh stent for unruptured brain aneurysms

  This trial tests the Choydar flow-directed mesh stent to see if it is safe and works for people with unruptured intracranial aneurysms in the internal carotid or vertebral arteries.

  Recruiting at 8 sites Johnson & Johnson Medical (Shanghai) Ltd. · Chenzhou and 7 other locations · NCT07228312

• Pivotal test of the Silk Vista Baby Flow Diverter for unruptured brain aneurysms

  This study tests whether the Silk Vista Baby flow diverter can safely and effectively treat a single unruptured intracranial aneurysm in adults 22–80 years old.

  Recruiting at 6 sites Balt USA · Thousand Oaks, California and 5 other locations · NCT07225075

• Pipeline Vantage post-approval safety and outcomes for intracranial aneurysm treatment

  This project will test whether the Pipeline Vantage embolization device with Shield Technology is safe and effective for adults treated for intracranial aneurysms.

  Recruiting at 10 sites Medtronic Neurovascular Clinical Affairs · Jacksonville, Florida and 9 other locations · NCT06604884

• Improving brain intervention planning using vascular mapping

  This study is testing new ways to plan brain surgeries for aneurysms and AVMs to make them safer and more effective by using advanced mapping and computer models.

  Recruiting University Hospital, Ghent · Ghent · NCT06588543

• Collecting real-life data on endovascular treatments for brain aneurysms

  This study is collecting real-life information on how safe and effective a specific type of device is for treating brain aneurysms in patients.

  Recruiting Microvention-Terumo, Inc. · Vigo, Pontevedra · NCT06494436

• Investigating factors related to intracranial aneurysms in China

  This study looks at what factors might cause or worsen brain aneurysms in people in China to help understand the risks better.

  Recruiting Zhujiang Hospital · Guangzhou · NCT06456814

• How blood flow changes after flow-diverter treatment for brain aneurysms

  We will test whether combining 3D angiography and transcranial Doppler can identify blood-flow thresholds linked to narrowing inside flow-diverter stents in adults treated for brain aneurysms.

  Recruiting Zhujiang Hospital · Guangzhou, Guangdong · NCT06448949

• Comparing general and local anesthesia for treating unruptured brain aneurysms

  This study is testing whether using local anesthesia instead of general anesthesia is a safe and effective option for adults with unruptured brain aneurysms during treatment.

  Recruiting Beijing Tiantan Hospital · Beijing, Beijing Municipality · NCT06416657

• Evaluation of a new device for treating brain aneurysms

  This study is testing a new device to treat brain aneurysms in patients who can't use other treatments or have had their aneurysms come back.

  Recruiting Phase 4 Federal State Budgetary Institution, V. A. Almazov Federal North-West Medical Research Centre, of the Ministry of Health · Saint Petersburg · NCT06400940

• Evaluating the Optima Coil System for treating intracranial aneurysms

  This study is testing the safety and effectiveness of the Optima Coil System for treating people with intracranial aneurysms, whether they are ruptured or not.

  Recruiting HCA Healthcare Research Institute · Plano, Texas · NCT06282939

• Registry evaluating flow diverters for treating brain aneurysms

  This study is testing different devices used to treat brain aneurysms to see which ones work best and are safest for patients.

  Recruiting at 8 sites Montefiore Medical Center · Coral Gables, Florida and 12 other locations · NCT06174727

• Blinded randomized test of an AI tool to find brain aneurysms on head CTA

  This trial will test whether an AI tool that helps read head CT angiograms can improve detection of brain aneurysms in adults having CTA scans.

  Recruiting at 21 sites Jinling Hospital, China · Hefei, Anhui and 20 other locations · NCT06118840

• Using placental models to train neurosurgeons for treating brain aneurysms

  This study is testing whether using placental tissue as a training tool can help neurosurgeons improve their skills in treating brain aneurysms.

  Recruiting University Hospital, Strasbourg, France · Strasbourg · NCT06117527

• Detecting microplastics in patients undergoing neurosurgery

  This study is trying to see if tiny pieces of plastic are found in the blood, brain fluid, and brain tissue of patients who are having brain surgery.

  Recruiting Beijing Tiantan Hospital · Beijing, Beijing Municipality · NCT05968053

• Evaluating the DERIVO® 2heal® Embolisation Device for treating intracranial aneurysms

  This study is testing a new device to see if it safely and effectively treats brain aneurysms in patients over a three-year period.

  Recruiting at 17 sites Acandis GmbH · Augsburg and 16 other locations · NCT05543447

• Integrated Biomedical Informatics for Managing Cerebral Aneurysms

  This study is trying to build a detailed database about brain aneurysms to see what factors might increase the risk of them forming or bursting, and it's for patients with aneurysms, healthy volunteers, and their family members.

  Recruiting at 15 sites University Hospital, Geneva · San Francisco, California and 21 other locations · NCT05526352

• Evaluating the safety and usability of BALT medical devices for various brain and vascular conditions

  This study is testing how safe and effective BALT medical devices are for treating brain and blood vessel conditions like aneurysms and strokes.

  Recruiting at 10 sites Balt Extrusion · Angers and 11 other locations · NCT04927156

• Managing unruptured intracranial aneurysms with different treatment options

  This study is testing whether surgery or a less invasive treatment is better for people with unruptured brain aneurysms compared to just monitoring their condition.

  Recruiting at 6 sites Centre hospitalier de l'Université de Montréal (CHUM) · Edmonton, Alberta and 5 other locations · NCT04155606

• Registry for managing aneurysmal subarachnoid hemorrhage in Switzerland

  This study is collecting information from patients in Switzerland who have had an aneurysmal subarachnoid hemorrhage to see how well they are treated and how they recover.

  Recruiting at 9 sites University Hospital, Geneva · Aarau, Canton of Aargau and 8 other locations · NCT03245866

• Treatment of wide-neck bifurcating intracranial aneurysms using the Artisse™ device

  This study is testing a new device called Artisse™ to see if it can safely and effectively treat wide-neck bifurcating brain aneurysms, both those that have and haven't ruptured.

  Recruiting at 25 sites Medtronic Neurovascular Clinical Affairs · Los Angeles, California and 24 other locations · NCT02998229

• Registry for monitoring neurovascular products used in treating brain aneurysms and strokes

  This study is tracking how well Medtronic devices work and their safety for people being treated for brain aneurysms and strokes.

  Recruiting at 37 sites Medtronic Neurovascular Clinical Affairs · Buenos Aires and 98 other locations · NCT02988128

• Registry for evaluating Medtronic products

  This study is collecting information to see how safe and effective Medtronic products are for patients who are using them.

  Recruiting at 381 sites Medtronic · Birmingham, Alabama and 401 other locations · NCT01524276

NIH-funded research (17)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Understanding how brain aneurysm walls and shape change over time

  This project studies how small brain aneurysms grow and whether MRI features of the aneurysm wall and its shape can predict growth so doctors can better decide when treatment is needed.

  NIH research University of Washington · Seattle, United States · NIH-11396260

• Predicting brain aneurysm growth with advanced 4D MRI and tensor math

  A research project uses 4D flow MRI and new math models to predict how brain aneurysms grow over time, helping doctors decide on safer treatments for people with UIAs.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11357552

• How aging and aged (senescent) cells may cause brain aneurysm rupture

  This research tests whether removing aging 'senescent' cells can lower the chance that a brain aneurysm will burst for people with intracranial aneurysms.

  NIH research St. Joseph's Hospital and Medical Center · Phoenix, United States · NIH-11308268

• Reprogramming blood-vessel lining cells in inherited brain aneurysms

  This project aims to find out whether fixing gene-related changes in the cells that line brain arteries can lower aneurysm risk in people with a family history.

  NIH research Yale University · New Haven, United States · NIH-11258496

• How tiny cell structures (podosomes) may weaken brain arteries and cause aneurysms

  Testing whether podosomes — small structures inside blood vessel cells — make brain arteries weaker and raise the risk of aneurysm rupture for people with or at risk of brain aneurysms.

  NIH research University of Texas Hlth Sci Ctr Houston · Houston, United States · NIH-11252802

• How cells' cleanup of vessel attachments may affect brain aneurysms

  This project looks at whether a cellular cleanup process in blood‑vessel lining cells weakens brain arteries and contributes to aneurysms in people at risk for intracranial aneurysm.

  NIH research University of Texas Hlth Sci Ctr Houston · Houston, United States · NIH-11251817

• Improved MRI methods to find small brain aneurysms likely to grow

  Using improved MRI scans to find inflammation and shape changes that show which small brain aneurysms may grow in people with unruptured aneurysms.

  NIH research University of Washington · Seattle, United States · NIH-11175416

• Predicting the growth of brain aneurysms using advanced imaging techniques

  This study is looking at how some brain aneurysms that don’t show any symptoms might change over time, using special MRI technology to help predict which ones could grow or burst in the next five years, so doctors can make better treatment choices for patients.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11101258

• Understanding how blood flow affects brain aneurysms

  This study is looking at how unusual blood flow can weaken the walls of brain aneurysms, with the goal of creating tools to help predict and prevent them from bursting, so it’s especially for people who have or are at risk for these conditions.

  NIH research University of California Los Angeles · Los Angeles, United States · NIH-11078673

• Investigating how aging and cell aging affect the risk of brain aneurysm rupture

  This study is looking at how getting older might increase the risk of brain aneurysms bursting and whether getting rid of certain aging cells can help prevent this, with the hope of finding new treatments that could benefit patients at risk.

  NIH research St. Joseph's Hospital and Medical Center · Phoenix, United States · NIH-11051893

• Investigating how certain genes affect blood vessel health in brain aneurysms

  This study is looking at the genes that might make some families more likely to have bulges in their brain blood vessels, which can be dangerous, and it's for anyone who has a family history of these aneurysms to help find ways to prevent them from causing serious problems.

  NIH research Yale University · New Haven, United States · NIH-11014420

• Investigating how podosomes affect blood vessel health and brain aneurysms

  This study is looking at tiny structures in brain cells that help keep blood vessels strong, especially in people at risk for brain aneurysms, to see how changes in blood flow might affect them and to find new ways to treat or prevent these aneurysms without surgery.

  NIH research University of Texas Hlth Sci Ctr Houston · Houston, United States · NIH-11004713

• Understanding how specific cell processes affect brain aneurysms

  This study is looking into how certain proteins in brain blood vessel cells might affect the growth of dangerous bulges called intracranial aneurysms, with the hope of finding new ways to help people who have this condition.

  NIH research University of Texas Hlth Sci Ctr Houston · Houston, United States · NIH-11000770

• Understanding factors that predict growth in brain aneurysms

  This study is looking at how certain features of unruptured brain aneurysms can help doctors figure out which ones might grow or burst, so they can better protect patients by focusing on those at higher risk, and you might get a special MRI scan to help with this research.

  NIH research University of Washington · Seattle, United States · NIH-10899533

• Understanding changes in brain arteries during the growth of aneurysms

  This study is looking at how certain blood vessels in the brain change when aneurysms grow, to help doctors better understand the risks of these aneurysms bursting and improve treatment for patients like you.

  NIH research University of California Los Angeles · Los Angeles, United States · NIH-10864056

• Understanding how certain blood cells contribute to the rupture of brain aneurysms

  This study is looking at how certain blood cells, called neutrophils and platelets, work together in the brain and might cause bulges in blood vessels, known as aneurysms, to burst, with the hope that understanding this could help improve treatments for patients with this condition.

  NIH research St. Joseph's Hospital and Medical Center · Phoenix, United States · NIH-10747874

• Investigating the role of a specific biological pathway in brain aneurysms

  This study is looking at how high blood pressure can cause brain aneurysms to burst, which can be very serious, and it aims to find new ways to help prevent this from happening, especially for people with hypertension.

  NIH research St. Joseph's Hospital and Medical Center · Phoenix, United States · NIH-10686891

Related topics

Quick answers

How many Intracranial Aneurysm clinical trials are recruiting right now?

24, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 43 countries. The most sites are in China (10 trials), United States (6 trials), France (6 trials), Canada (5 trials), Germany (5 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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