Understanding factors that predict growth in brain aneurysms
Investigation of the quantitative intracranial aneurysm wall enhancement and geometric features associated with aneurysm volume growth
This study is looking at how certain features of unruptured brain aneurysms can help doctors figure out which ones might grow or burst, so they can better protect patients by focusing on those at higher risk, and you might get a special MRI scan to help with this research.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Washington NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-10899533 on NIH RePORTER |
What this research studies
This research investigates how certain features of unruptured intracranial aneurysms (UIAs), such as their wall enhancement and geometric characteristics, can help predict which aneurysms are likely to grow and potentially rupture. By using advanced imaging techniques, the study aims to identify small aneurysms that may be at higher risk, even if they are below the current treatment threshold. The goal is to improve patient outcomes by enabling more targeted interventions for those at greatest risk. Patients may undergo specialized MRI scans to assess their aneurysms as part of this research.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with diagnosed unruptured intracranial aneurysms, particularly those smaller than 7mm.
Not a fit: Patients with ruptured aneurysms or those without any diagnosed aneurysms may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better identification and treatment of high-risk aneurysms, potentially preventing life-threatening ruptures.
How similar studies have performed: Previous research has shown that identifying growth in aneurysms significantly correlates with rupture risk, suggesting that this approach has potential for success.
Where this research is happening
Seattle, United States
- University of Washington — Seattle, United States (Active)
Researchers
- Principal investigator: Zhu, Chengcheng — University of Washington
- Study coordinator: Zhu, Chengcheng
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.