Understanding changes in brain arteries during the growth of aneurysms
Investigation of arterial changes in the Circle of Willis during intracranial aneurysm growth in humans
['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA LOS ANGELES · NIH-10864056
This study is looking at how certain blood vessels in the brain change when aneurysms grow, to help doctors better understand the risks of these aneurysms bursting and improve treatment for patients like you.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA LOS ANGELES (nih funded) |
| Locations | 1 site (LOS ANGELES, UNITED STATES) |
| Trial ID | NIH-10864056 on ClinicalTrials.gov |
What this research studies
This research investigates how the arteries in the Circle of Willis, a critical area in the brain, change as intracranial aneurysms grow. By using advanced imaging techniques, the study aims to identify specific vascular changes that could indicate the risk of aneurysm rupture. The research focuses on understanding the biochemical processes involved in aneurysm growth and how blood flow dynamics affect these processes. Patients may be monitored to better predict aneurysm progression and improve treatment strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with intracranial aneurysms, particularly those who are asymptomatic but at risk of growth.
Not a fit: Patients without intracranial aneurysms or those with other unrelated vascular conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved monitoring and treatment options for patients with intracranial aneurysms, potentially reducing the risk of rupture.
How similar studies have performed: Previous research has shown promising results in understanding vascular changes related to aneurysm growth, indicating that this approach may yield valuable insights.
Where this research is happening
LOS ANGELES, UNITED STATES
- UNIVERSITY OF CALIFORNIA LOS ANGELES — LOS ANGELES, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: CHIEN, AICHI — UNIVERSITY OF CALIFORNIA LOS ANGELES
- Study coordinator: CHIEN, AICHI
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Disorder