Improving brain intervention planning using vascular mapping
Patient-specific Planning of Minimally Invasive Brain Interventions Based on Vascular-hemodynamic Mapping
This study is testing new ways to plan brain surgeries for aneurysms and AVMs to make them safer and more effective by using advanced mapping and computer models.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 500 (estimated) |
| Sex | All |
| Sponsor | University Hospital, Ghent Academic / other |
| Drugs / interventions | radiation |
| Locations | 1 site (Ghent) |
| Trial ID | NCT06588543 on ClinicalTrials.gov |
What this trial studies
This study focuses on enhancing the safety and efficiency of endovascular procedures for treating brain aneurysms and arteriovenous malformations (AVMs) through innovative preoperative planning methodologies. By utilizing advanced mapping of cerebral vasculature and creating computational fluid dynamics (CFD) and artificial intelligence (AI) models, the study aims to simulate blood flow and improve catheter navigation. This approach seeks to reduce the risk of complications and radiation exposure during procedures, ultimately leading to faster and more accurate interventions.
Who should consider this trial
Good fit: Ideal candidates for this study are patients diagnosed with an aneurysm or arteriovenous malformation who are undergoing endovascular embolization or coiling.
Not a fit: Patients who are not undergoing imaging during their procedures may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to safer and more effective endovascular treatments for patients with brain aneurysms and AVMs.
How similar studies have performed: Other studies have shown promise in using advanced imaging and modeling techniques for similar endovascular procedures, indicating a potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Subjects who are diagnosed with aneurysm or arteriovenous malformation * Subjects who are treated (or will be treated) with endovascular embolization and/or arteriovenous coiling * During and before/after the subject's intervention, medical images (MRI, 3D rotational angiography, DSA) were collected of the cerebral arterial vascular tree (which can be used to develop patient-specific models), including catheter location and use of contrast fluid to visualize the cerebral to make the arterial tree more visible. Exclusion Criteria: -Procedures during which no imaging was performed
Where this trial is running
Ghent
- University Hospital Ghent — Ghent, Belgium (Recruiting)
Study contacts
- Study coordinator: Peter Vanlangenhove, Prof. Dr.
- Email: peter.vanlangenhove@uzgent.be
- Phone: +32 9 3323112
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.