VR-based cognitive games to help prevent delirium after big surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This pilot randomized trial tests the feasibility, safety, and acceptability of a virtual reality (VR) cognitive stimulation program for high-risk older adults after major surgery. Participants are randomized to one of three arms: VR-based cognitive games, VR movie viewing, or nurse-led reality orientation. The study will look at cognitive function, especially sustained attention, and the incidence of postoperative delirium. Enrolled patients are 65 years or older with pre-existing cognitive impairment and expected ICU admission for at least three days after surgery. The trial is conducted at Houston Methodist facilities with collaboration from the National Institute on Aging.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Men and women ≥65 years of age
* Have a pre-existing diagnosis of cognitive impairment (Montreal Cognitive Assessment Score of 15-24)
* Elective or emergency major surgery with the expectation of admission to the Intensive Care Unit following the surgery for three days following surgery

Exclusion Criteria:

* Pre-existing Intubation and invasive ventilation;
* history of severe mental illness;
* admission for a drug overdose;
* severe vertigo;
* history of severe postoperative nausea and vomiting;
* hearing and visual impairment;
* preexisting severe dementia (Montreal Cognitive Assessment Score \< 15; and
* active delirium at the time of screening for eligibility criteria.
* Active suicidal ideation or behavior Screen failure after surgery
* Prolonged intubation after surgery (more than 24 hours)

Where it's running

• Houston Methodist Hospital
  Houston, Texas, United States Recruiting
• Houston Methodist Research Insititute
  Houston, Texas, United States Recruiting

Study contacts

• Principal investigator: Hina Faisal, MD — The Methodist Hospital Research Institute
• Study coordinator: Hina Faisal, MD
• Email: hfaisal@houstonmethodist.org
• Phone: 346-356-1400

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.