Using EEG to predict postoperative delirium in neurosurgery patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to determine if sub-hairline electroencephalography (EEG) can reliably predict postoperative delirium (POD) in adult patients undergoing elective craniotomy. Patients will have their EEG monitored during the immediate recovery phase in the ICU, focusing on specific brain regions and frequency bands. The study seeks to identify EEG parameters that correlate with the onset of POD, which is a common complication following major neurosurgery. By understanding these predictive markers, the study hopes to improve early identification and management of at-risk patients.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age ≥ 18 years
* Planned elective neurosurgical surgery
* ASA physical status I-II
* Signed informed consent

Exclusion Criteria:

* Known neurological or psychiatric disorders (e.g., epilepsy, Parkinson's disease)
* Preoperative cognitive impairment (MMSE score \< 24)
* Long-term use of central nervous system drugs (e.g., antidepressants, antipsychotics)
* Language barriers
* History of craniotomy within the last 12 months
* Inability to place frontal-temporal electrodes due to conditions such as frontal skin injury, severe agitation, or a coronal incision for surgery
* Pregnant or breastfeeding women

Where it's running

• Beijing Sanbo Brain Hospital, Capital Medical University
  Beijing, Beijing Municipality, China Recruiting
• Sanbo Brain Hospital, Captial Medical Universtiy
  Beijing, Beijing Municipality, China Recruiting

Study contacts

• Principal investigator: Zhonghua Shi, PhD,MD — Capital Medical University
• Study coordinator: Zhonghua Shi, PhD,MD
• Email: z.shi@mail.ccmu.edu.cn
• Phone: 010-62856764

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.