Early activation and sleep-promoting routines to reduce delirium after CABG

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized controlled trial will compare the DREAMS-OT program—early, intensive occupational therapy plus structured sleep-promoting routines—to standard post-CABG care. Adults aged 21 and over scheduled for elective CABG at National University Hospital Singapore who can consent and speak English or Mandarin will be enrolled and randomized to intervention or control. The primary outcome is the incidence of postoperative delirium within five days after surgery, and the study will also evaluate the cost-effectiveness of the intervention. Patients with severe preexisting cognitive or sensory impairments, those who develop delirium before the intervention, or those with unstable surgical complications are excluded.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients deemed medically suitable for elective CABG surgery
* Patients aged 21 years and above
* Patients who are English or Mandarin speaking.
* Patients who are able to provide consent

Exclusion Criteria:

* Patients who speak other languages are excluded due to the language requirements of certain outcome measures.
* Patients with premorbid severe hearing impairment, severe cognitive impairment, progressive neurological disorders and psychological disorders will be excluded.
* Patients with surgical complications resulting in profuse bleeding from any invasive sites, septic shock unresponsive to maximal treatment, and those who are moribund or have an expected mortality within 48 hours will be excluded.
* Pregnant women will also be excluded from the study as well.
* Patients who develop delirium before initiation of the treatment are also excluded from the study.

Where it's running

• National University Hospital
  Singapore, Singapore Recruiting

Study contacts

• Principal investigator: Su Ren Wong — National University Hospital, Singapore
• Study coordinator: Megan HL Tan
• Email: megan_huei_lin_tan@nuhs.edu.sg
• Phone: +65-96280613

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.