Dexmedetomidine to See if Delirium Drops After Hip Fracture Surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Postoperative delirium is a common complication after hip fracture surgery, particularly in elderly patients with multiple health issues. This study examines whether implementing intraoperative dexmedetomidine prophylaxis reduces delirium by comparing outcomes before and after the prophylaxis program. Data will be drawn from patients undergoing hip fracture surgery under general or spinal anesthesia during defined pre- and post-implementation periods. Exclusion criteria include hypersensitivity to dexmedetomidine, certain heart rhythm blocks without a pacemaker, acute cerebral conditions affecting autoregulation, and severe liver failure. The study is led by Peter Gaarsdal Uhrbrand at Aarhus University Hospital with anesthesiology staff as the collaborating team.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients at least 65 years of age undergoing surgery for hip fracture in general or spinal anesthesia
* Treated during the defined pre- or post-implementation period

Exclusion Criteria:

* Known hypersensitivity to dexmedetomidine
* Second- or third-degree AV block without pacemaker
* Acute cerebral conditions with potentially impaired cerebral autoregulation
* Acute or chronic liver failure

Where it's running

• Department of Anesthesiology, Aarhus University Hospital
  Aarhus, Denmark Recruiting

Study contacts

• Study coordinator: Peter G. Uhrbrand, MD, PhD
• Email: petuhr@rm.dk
• Phone: +4530615082

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.