Condition

Cardiovascular Diseases (CVD) clinical trials and research

• 26Clinical trials
• 4NIH research projects
• 1New in 30 days
• 17Countries

Newest Cardiovascular Diseases (CVD) clinical trials

All recruiting trials (26)

• Tailored digital support to cut sedentary time in long-term cardiac rehab

  In adults in a long-term cardiac rehabilitation program, this study tests whether a personalized behavioural program with digital tools can reduce daily sitting time.

  Recruiting University of Lisbon · Lisbon, Lisbon District · NCT07910812

• Health for Hungary: Long-term blood and health data collection to study aging and disease onset

  This study tests whether routine blood tests plus advanced molecular analyses can help detect the early stages of non-communicable diseases in adults over 40.

  Recruiting at 21 sites Center for Molecular Fingerprinting Research Nonprofit LLC · Balatonfüred and 32 other locations · NCT07743021

• Inulin Prebiotic for Perimenopausal Women with Overweight or Obesity

  This study tests whether 2 weeks of inulin can affect gut and vaginal microbes, heart health, and muscle health in perimenopausal women who are overweight or obese, using a crossover design.

  Recruiting George Washington University · Washington D.C., District of Columbia · NCT07724522

• Colchicine to see if it reduces coronary artery inflammation in people with HIV

  This study tests whether low-dose colchicine can lower inflammation in the coronary arteries of people with HIV who are at high heart-disease risk, compared with a placebo.

  Recruiting at 2 sites Phase 2 Instituto de Investigación Hospital Universitario La Paz · Barcelona and 3 other locations · NCT07704164

• Transcatheter Tricuspid Valve Replacement for Severe Tricuspid Regurgitation

  This trial tests the Laplace TTVR System to see if it safely and effectively treats adults with severe tricuspid regurgitation.

  Recruiting at 2 sites Laplace Interventional, Inc · Tulsa, Oklahoma and 1 other locations · NCT07687485

• A lifetime registry and imaging database for people with heart, kidney, and metabolic conditions

  This project will see if creating a long-term clinical and imaging database for adults with heart, kidney, or metabolic conditions can improve prediction of outcomes and guide care.

  Recruiting First Affiliated Hospital of Fujian Medical University · Fuzhou, Fujian · NCT07547098

• Vyne TriNova Transcatheter Tricuspid Valve Replacement study for severe tricuspid regurgitation

  This trial tests the VDyne TriNova system in adults with symptomatic severe tricuspid regurgitation to see if it is safe and helps heart symptoms compared with an alternative device.

  Recruiting at 12 sites VDyne, Inc. · Phoenix, Arizona and 11 other locations · NCT07516444

• 6-week gut microbiome prep before heart surgery to see if it improves outcomes and saves NHS costs

  A 6-week preoperative test using WellBiome or placebo in people needing heart surgery to see if gut bacteria changes can improve recovery and reduce costs.

  Recruiting Hull University Teaching Hospitals NHS Trust · Hull, East Riding Of Yorkshire · NCT07483502

• Heart Institute Biorepository for children with heart disease

  This project collects and stores blood, tissue, and other samples from people with pediatric heart disease so researchers can use them to learn more and develop new tests and treatments.

  Recruiting Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT07478354

• Using wearable data to predict heart health and cardiovascular risk

  This will test whether continuous Fitbit data can help track and predict heart health and future cardiovascular risk in adults.

  Recruiting University College Dublin · Dublin, Dublin · NCT07401550

• Long-term registry for Korean patients with heart and brain vascular disease

  This project will collect past and ongoing medical records to see if combining them improves prediction of future health outcomes for Korean patients with heart and blood vessel diseases.

  Recruiting Samsung Medical Center · Seoul · NCT07393412

• 10-year follow-up of adults screened for heart risk to create a Morocco-specific heart risk score

  This project will try to see if information from people screened 10 years ago can be used to build a heart disease risk score tailored for Moroccan adults age 40 and older.

  Recruiting at 2 sites Moroccan Society of Cardiology · Casablanca and 1 other locations · NCT07294937

• BrioVAD Heart Pump for advanced heart failure in adults

  A BrioVAD heart pump is being tested in adults with severe, treatment-refractory heart failure to see if it can safely support the heart without needing device replacement within 6 months.

  Recruiting at 2 sites BrioHealth BV · Rotterdam and 1 other locations · NCT07252531

• Combining genetics, blood, urine, and stool data to predict complications of metabolic syndrome

  The team will try combining genetic, blood, urine, and stool data to see if patterns predict complications in adults with or without metabolic syndrome.

  Recruiting Chang Gung Memorial Hospital · Taoyuan · NCT07248371

• Multi-center artificial intelligence-based quantitative echocardiography evaluation

  This project will test whether AI can automatically and accurately measure heart chamber sizes, volumes, and function from echocardiograms in adults with common cardiovascular conditions.

  Recruiting at 37 sites First Hospital of China Medical University · Huainan, Anhui and 36 other locations · NCT07133516

• Ambient air and noise effects on heart and metabolic health with green-space exercise and Mediterranean diet (METSGREEN)

  This project will test whether exposure to ultrafine air pollution and urban noise raises heart and metabolic risk and whether daily green-space exercise or a Mediterranean diet can lower that risk in 45–64-year-old Kaunas residents with early metabolic problems.

  Recruiting Vytautas Magnus University · Kaunas, Kaunas County and 1 other locations · NCT07111208

• 68Ga-FAPI PET combined with cardiac MRI for heart disease

  This project will test whether 68Ga-FAPI PET together with cardiac MRI can find early scarring (fibrosis) of the heart muscle in adults with cardiovascular disease.

  Recruiting Shanghai East Hospital · Shanghai, Shanghai Municipality · NCT07063043

• Heart, kidney, and metabolic health in Shanghai community residents

  This follow-up will track people from the STONE cohort to see if changes in metabolic risk factors over time relate to heart and kidney outcomes.

  Recruiting Shanghai Changzheng Hospital · Shanghai, Shanghai Municipality · NCT07043166

• Exercise to help reduce antidepressant use in people with heart-related depression and anxiety

  This project will try whether regular moderate exercise helps adults with cardiovascular disease and long-term depression or anxiety safely reduce their SSRI/SNRI medications.

  Recruiting Guangdong Provincial People's Hospital · Guangzhou, Guangdong · NCT07025590

• Personalized approaches to prevent non-communicable diseases in Kazakhstan

  This study is trying to see if analyzing DNA can help create personalized health plans to prevent diseases like heart problems and diabetes for people in Kazakhstan.

  Recruiting Asfendiyarov Kazakh National Medical University · Almaty, Kazakhstan · NCT06953180

• Using royal jelly to reduce inflammation and oxidative stress in people with high blood pressure

  This study is testing if royal jelly can help reduce inflammation and oxidative stress in people with high blood pressure who are already taking medication.

  Recruiting Universidade Federal Fluminense · Rio de Janeiro, Rio de Janeiro · NCT06917131

• Effect of Roxadustat on heart health and nutrition in hemodialysis patients

  This study is testing if the medication Roxadustat can improve heart health and nutrition in people with kidney disease who are on hemodialysis, compared to standard anemia treatments.

  Recruiting Phase 1/2 Mansoura University · Al Mansurah, Dakahliya · NCT06903559

• Stress-management program to reduce heart disease risk in women with HIV

  This program will test whether the SMART stress-management intervention can lower blood pressure and other heart-disease risks for women living with HIV in the Southern US.

  Recruiting University of Alabama at Birmingham · Birmingham, Alabama · NCT06811896

• Understanding COPD and cardiovascular disease in Greece

  This study is trying to learn more about people in Greece who have both COPD and heart disease to see how these conditions affect their lives and healthcare needs over two years.

  Recruiting at 2 sites Hellenic Thoracic Society · Alexandroupoli and 1 other locations · NCT06595784

• Using sivelestat to protect lung function after heart surgery

  This study is testing if giving sivelestat to patients having emergency heart surgery can help protect their lungs and improve recovery by reducing serious complications.

  Recruiting at 2 sites Nanjing Medical University · Beijing and 1 other locations · NCT06195267

• Monitoring cardiovascular rehabilitation outcomes in Switzerland

  This study looks at how a 12-week heart rehabilitation program in Switzerland affects patients' heart health and helps identify those at higher risk for heart problems.

  Recruiting University Hospital, Basel, Switzerland · Basel · NCT05500859

NIH-funded research (4)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Understanding what raises heart disease risk in people with well-controlled type 1 diabetes

  Researchers are studying why some people with type 1 diabetes still develop heart disease even when traditional risk factors are controlled.

  NIH research Joslin Diabetes Center · Boston, United States · NIH-11365901

• Understanding Heart Disease Risks in People with Well-Controlled Type 1 Diabetes

  This project looks at why people with Type 1 diabetes might still get heart disease, even when their other health factors are well-managed.

  NIH research Joslin Diabetes Center · Boston, United States · NIH-11194457

• Investigating cardiovascular disease risks in people with well-controlled type 1 diabetes

  This study is looking into why people with well-managed type 1 diabetes still have a higher chance of heart problems, by comparing their heart and blood samples with those from people with type 2 diabetes and those without diabetes, to find out what makes their risks different.

  NIH research Joslin Diabetes Center · Boston, United States · NIH-11074281

• Understanding heart disease in people with long-term Type 1 diabetes

  This study is looking at how heart disease develops in people who have had Type 1 diabetes for a long time, to find out what makes their risk different from those with Type 2 diabetes, and it’s for anyone with a long history of Type 1 diabetes who wants to understand more about their heart health.

  NIH research Joslin Diabetes Center · Boston, United States · NIH-10991330

Related topics

Quick answers

How many Cardiovascular Diseases (CVD) clinical trials are recruiting right now?

26, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 17 countries. The most sites are in China (6 trials), United States (5 trials), Switzerland (1 trial), Lithuania (1 trial), Ireland (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1/2: 1, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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