Using royal jelly to reduce inflammation and oxidative stress in people with high blood pressure

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effects of royal jelly on inflammation and oxidative stress in individuals with systemic arterial hypertension. It is designed as a longitudinal double-blind randomized clinical trial lasting two months, involving participants who are already on antihypertensive medications. The research aims to explore the potential of royal jelly, known for its antioxidant and anti-inflammatory properties, as a natural supplement for managing hypertension. The study will compare the effects of royal jelly against a placebo to determine its efficacy in improving health outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Diagnosis of stage 1 hypertension
* Regular treatment for more than 6 months
* No changes in medication doses during the last 3 months

Exclusion Criteria:

* Autoimmune diseases
* Infectious diseases
* Diabetes
* Chronic kidney disease
* Liver disease
* Cancer
* AIDS
* Pregnant women
* Use of catabolic drugs or antibiotics
* Use of antioxidant vitamin supplements, prebiotics, probiotics, or synbiotics
* Habitual intake of royal jelly
* Allergy to bee stings
* Acute myocardial infarction (AMI)
* Stroke (CVA)

Where it's running

• Denise Mafra
  Rio de Janeiro, Rio de Janeiro, Brazil Recruiting

Study contacts

• Principal investigator: Ludmila Cardozo, PhD — Universidade Federal Fluminense
• Study coordinator: Denise mafra, PhD
• Email: dmafra30@gmail.com
• Phone: +5521985683003

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.