Heart, kidney, and metabolic health in Shanghai community residents
Official title: Epidemiological Survey and Follow-up of Cardiovascular-Kidney-Metabolic Diseases Among Adults in Shanghai
Run by Shanghai Changzheng Hospital · NCT07043166 · Data updated 2026-11-12
This follow-up will track people from the STONE cohort to see if changes in metabolic risk factors over time relate to heart and kidney outcomes.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 4094 (estimated) |
| Sponsor | Shanghai Changzheng Hospital Academic / other |
| Locations | 1 site (Shanghai, Shanghai Municipality) |
| Status | Recruiting |
| Started | July 1, 2025 |
| Main results expected | May 30, 2035 |
| Study ends | December 31, 2035 |
| Registry record updated | September 8, 2025 |
| Trial ID | NCT07043166 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults from the original STONE cohort who completed the 2016–2017 baseline exams, remain contactable, and consent to follow-up.
✕Probably not a fit
People who moved away, cannot be reached after multiple attempts, or were excluded at baseline for serious illnesses are unlikely to benefit from participation.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Researchers will re-contact the >4,000 adults enrolled in the STONE cohort in 2016–2017 and repeat questionnaires, physical exams, labs, and imaging to update cardiorenal outcomes. Participants will be grouped by CKM staging and metabolic risk profiles to compare current findings with baseline measures. The planned data collection for the cohort begins May 2025 with population-level data finalized by June 2026 and extended follow-up through 2035. The protocol excludes those who moved away or cannot be contacted and relies on visits at Shanghai Changzheng Hospital for testing.
Why it matters
Potential benefit: If successful, this work could identify which metabolic changes predict worsening heart or kidney health so clinicians can target prevention earlier.
How similar studies have gone: Large longitudinal cohort studies have previously linked metabolic risk factors to cardiovascular and kidney outcomes, so the approach is established though this cohort provides region-specific data.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. The 4,094 residents of Shanghai communities who have been enrolled in the STONE cohort. 2. Individuals who completed the baseline questionnaire survey, physical examination, and related clinical tests between 2016 and 2017, with complete data records. 3. Willingness to participate in this follow-up study and provision of informed consent. Exclusion Criteria: 1. Participants who have moved away from their original community and have been living elsewhere for more than two years. 2. Participants whose contact information has changed or become invalid, resulting in loss of contact (those who remain uncontactable after three attempts to reach out).
Where it's running
-
Shanghai Changzheng Hospital
Shanghai, Shanghai Municipality, China Recruiting
Study contacts
- Study coordinator: tuo Tuo Li, Doctor
- Email: dr.lituo@smmu.edu.cn
- Phone: 86-13918507887
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.