Effect of Roxadustat on heart health and nutrition in hemodialysis patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the effects of Roxadustat, an oral medication, on anemia, cardiovascular health, and Malnutrition-Inflammation-Atherosclerosis (MIA) syndrome in patients with end-stage kidney disease undergoing hemodialysis. Participants will be randomly assigned to receive either Roxadustat or conventional anemia treatments, with their heart function, nutritional markers, inflammation levels, and anemia status monitored over a six-month period. The study aims to determine if Roxadustat provides additional benefits beyond correcting hemoglobin levels.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age of patient is more than 18.
* Patients who are willing to sign informed consent.
* Patients with ESKD on chronic hemodialysis for more than 3 months.

Exclusion Criteria:

* Current pregnancy or lactation.
* Patients with pre-existing malignancy.
* Patients with psychosis or on hypnotics.
* Refuse to participate in the study.
* Known history of hematological disorders or other known causes for anemia other than CKD or dialysis.
* Patients with severe cardiovascular disease

Where it's running

• Urology and Nephrology Center, Mansoura University
  Al Mansurah, Dakahliya, Egypt Recruiting

Study contacts

• Study coordinator: Ibrahim M Galalah, MSC
• Email: ibrahimgalalah@gmail.com
• Phone: +201027794586

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.