Understanding heart disease in people with long-term Type 1 diabetes
Characterization of cardiovascular diseases (CVD) in people with long duration Type 1 diabetes
This study is looking at how heart disease develops in people who have had Type 1 diabetes for a long time, to find out what makes their risk different from those with Type 2 diabetes, and it’s for anyone with a long history of Type 1 diabetes who wants to understand more about their heart health.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Joslin Diabetes Center NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10991330 on NIH RePORTER |
What this research studies
This research investigates how cardiovascular diseases (CVD) develop in individuals with long-duration Type 1 diabetes (T1D). It aims to identify the unique risk factors and mechanisms that contribute to CVD in T1D compared to Type 2 diabetes. By analyzing data from a large cohort of individuals with over 50 years of T1D, the study will explore the relationship between diabetes-related complications, such as diabetic nephropathy, and heart disease. The research will utilize advanced imaging techniques and genetic analysis to better understand the underlying causes of CVD in this population.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with long-duration Type 1 diabetes, particularly those who may or may not have diabetic nephropathy.
Not a fit: Patients with Type 2 diabetes or those without a history of diabetes may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention and treatment strategies for cardiovascular diseases in patients with Type 1 diabetes.
How similar studies have performed: Previous studies have shown that understanding the unique cardiovascular risks in diabetes can lead to significant advancements in patient care, suggesting this research could build on established findings.
Where this research is happening
Boston, United States
- Joslin Diabetes Center — Boston, United States (Active)
Researchers
- Principal investigator: King, George L — Joslin Diabetes Center
- Study coordinator: King, George L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.