Condition

Coronary Artery Disease (CAD) clinical trials and research

• 39Clinical trials
• 1New in 30 days
• 20Countries

Newest Coronary Artery Disease (CAD) clinical trials

All recruiting trials (39)

• TAVI and PCI vs SAVR and CABG in low- and intermediate-risk patients with severe aortic stenosis and CAD

  This observational study compares TAVI plus PCI to SAVR plus CABG for patients who have both severe aortic stenosis and coronary artery disease.

  Recruiting Alexandria University · Alexandria, Alexandira · NCT07926022

• Resveratrol and Estrogen Receptors in Postmenopausal Women with CAD

  This study tests whether taking resveratrol is safe and can change estrogen-related markers in postmenopausal women with coronary artery disease.

  Recruiting InCor Heart Institute · São Paulo, São Paulo · NCT07865377

• Predicting Plaque Growth Using Blood Flow Stress Markers

  This study tests whether combining blood flow patterns in the heart arteries with how blood-flow–sensitive cells respond can help predict which plaques will grow in people with coronary artery disease.

  Recruiting Queen Mary University of London · London · NCT07864051

• Identifying Coronary Plaque Traits with Photon-counting CT and Multimodality Imaging

  This study tests whether advanced imaging can better identify risky artery plaques in people with stable angina.

  Recruiting Queen Mary University of London · London · NCT07864025

• Health for Hungary: Long-term blood and health data collection to study aging and disease onset

  This study tests whether routine blood tests plus advanced molecular analyses can help detect the early stages of non-communicable diseases in adults over 40.

  Recruiting at 21 sites Center for Molecular Fingerprinting Research Nonprofit LLC · Balatonfüred and 32 other locations · NCT07743021

• Coronary Extension Catheter in PCI for CAD patients

  This study tests whether using a coronary extension catheter during PCI helps adults with coronary artery disease.

  Recruiting BrosMed Medical Co., Ltd · Beijing · NCT07742345

• Cardiac rehab in CAD: does it affect ferroptosis?

  This study tests whether a structured cardiac rehabilitation program changes ferroptosis markers in people with coronary artery disease compared with those who don’t participate and healthy volunteers.

  Recruiting TC Erciyes University · Kayseri, Kayseri · NCT07722637

• IVUS-Guided Left Main Stenting: IVUS-Guided vs Trained-Eye Approach

  This trial tests whether using IVUS to guide left main bifurcation stenting is as good as using an angiography-driven, experience-based approach by an IVUS-savvy operator.

  Recruiting Federal State Budgetary Institution, V. A. Almazov Federal North-West Medical Research Centre, of the Ministry of Health · Saint Petersburg · NCT07711106

• Mobile-based home cardiac rehab to see if it reduces non-calcified coronary plaque

  A mobile, at-home cardiac rehabilitation program is being tested to see if it can reduce non-calcified plaque in people with mild to moderate coronary artery narrowing.

  Recruiting China National Center for Cardiovascular Diseases · Beijing · NCT07660419

• Effects of Myofascial Release on Heart Patients After Sternotomy

  This study tests whether myofascial release can improve breathing and chest mobility after heart surgery in adults with certain heart diseases.

  Recruiting Kaohsiung Veterans General Hospital. · Kaohsiung City · NCT07649330

• Crossover vs Accurate Ostial Stenting for Left Main Bifurcation Lesions

  This observational study tests two stenting strategies for ostial lesions in the left main coronary artery to see which approach works better for patients with left main bifurcation disease.

  Recruiting Istanbul Mehmet Akif Ersoy Educational and Training Hospital · Istanbul, Please Select and 1 other locations · NCT07596706

• eCardiacRehab: a home-based, patient-centered cardiac rehab program

  This trial tests a hybrid home-based cardiac rehabilitation program to see if it reduces cardiovascular deaths and ED visits while improving quality of life for adults with CAD after PCI, compared with usual care.

  Recruiting Haukeland University Hospital · Bergen · NCT07590635

• AI-assisted cardiac CT to predict coronary artery disease risk

  This project will try using AI-enhanced heart CT scans to better predict future coronary events in adults who are already getting a clinical cardiac CT.

  Recruiting University of Galway · Galway · NCT07577609

• Paired intracoronary OCT and coronary CT angiography to map plaque and blockages

  This project will test whether advanced coronary CT scans can provide the same detailed plaque and blockage information as invasive intracoronary optical coherence tomography (OCT) in adults with coronary artery disease who have both scans.

  Recruiting Insel Gruppe AG, University Hospital Bern · Bern · NCT07565805

• Multi-omics search for clotting and bleeding markers in coronary heart disease

  This project will test whether combining proteins, metabolites, genes, sugar tags, and heart images can better predict clotting and major bleeding in people with coronary heart disease on dual antiplatelet therapy.

  Recruiting at 3 sites Chinese Academy of Medical Sciences, Fuwai Hospital · Zhengzhou, Henan and 2 other locations · NCT07523880

• Inspiron EVO stent in complex coronary lesions in Brazil

  This study tests how well and safely the Inspiron EVO drug-eluting stent works in real-world patients with complex coronary artery disease in Brazil.

  Recruiting Scitech Produtos Medicos SA · Porto Alegre, Rio Grande do Sul · NCT07491107

• NAVIGATE-PCI: Using CT images to guide planning for elective stenting.

  This registry will try CT-based PCI Navigator guidance to see if it helps cardiologists plan elective stenting for patients with stable coronary artery disease.

  Recruiting HeartFlow, Inc. · Marietta, Georgia · NCT07479433

• Fexuprazan to prevent upper gastrointestinal bleeding in high-bleeding-risk patients on dual antiplatelet therapy after stent placement

  This will test whether taking fexuprazan once daily for six months reduces upper gastrointestinal bleeding in people at high bleeding risk who need dual antiplatelet therapy after coronary stent placement.

  Recruiting Eunpyeong St. Mary's Hospital · Seoul, Eunpyeong-gu · NCT07479056

• Better care for people with recent-onset stable chest pain

  This project will test a new nationwide care model that uses coronary CT instead of routine cardiac catheterization for adults 30 and older with recent-onset stable chest pain to see if it lowers heart attacks, strokes, and healthcare costs.

  Recruiting at 39 sites Philipps University Marburg · Augsburg and 38 other locations · NCT07476040

• Drug-coated balloons versus drug-eluting stents for chronic total occlusion of coronary arteries

  This will test whether using drug-coated balloons (alone or with a stent when needed) works as well as drug-eluting stents alone for people whose chronically blocked coronary artery has been successfully opened.

  Recruiting at 9 sites The First Affiliated Hospital of Zhengzhou University · Beijing, Beijing Municipality and 17 other locations · NCT07463664

• Erectile function changes after coronary stent procedures for heart attack versus stable angina

  We will see if erectile function gets better or worse over 3 and 6 months in men who had a successful PCI (stent procedure) for a heart attack or for stable angina.

  Recruiting Kırıkkale University · Kirikkale · NCT07444697

• Using wearable data to predict heart health and cardiovascular risk

  This will test whether continuous Fitbit data can help track and predict heart health and future cardiovascular risk in adults.

  Recruiting University College Dublin · Dublin, Dublin · NCT07401550

• Using the ulnar artery when the same-arm radial artery is blocked for heart angiography or angioplasty

  This study will try using the ulnar artery in the same arm with a blocked radial artery to see if it's safe and how it affects hand strength, feeling, and everyday hand use in adults having coronary angiography or angioplasty.

  Recruiting at 2 sites National and Kapodistrian University of Athens · Athens and 1 other locations · NCT07380399

• Mindfulness for Women with Coronary Artery Disease

  This study tests whether a mindfulness-based program helps women with coronary artery disease reduce stress and improve quality of life.

  Recruiting TC Erciyes University · Kayseri, Türki̇ye · NCT07371806

• Drug-coated balloon vs. drug-eluting stent in high-risk coronary artery disease

  This trial tests whether a SeQuent SCB strategy can match the performance of a new-generation DES in high-risk CAD patients, over 12 and 36 months.

  Recruiting B. Braun Melsungen AG · Homburg and 2 other locations · NCT07363161

• EA-230 to shorten hospital stay after CABG surgery in adults

  EA-230 is being tested to see if it helps adults recovering from CABG surgery by shortening their hospital stay.

  Recruiting at 3 sites Phase 3 EBI Anti Sepsis BV · Rochester, Minnesota and 5 other locations · NCT07357675

• Low-dose colchicine for people with non-flow-limiting coronary plaque seen on CT

  This trial tests whether taking 0.5 mg of colchicine once daily on top of usual heart medicines can lower the chance of heart attack, stroke, or need for coronary procedures in adults with stable coronary artery disease and non-flow-limiting plaques on coronary CT.

  Recruiting Phase 4 Nanjing First Hospital, Nanjing Medical University · Nanjing · NCT07349875

• SRSD107 for people with chronic coronary or peripheral arterial disease

  This trial will test different doses of SRSD107 to see if they are safe and produce the expected drug effects in adults with chronic coronary or peripheral arterial disease who are taking aspirin.

  Recruiting Phase 2 Sirius Therapeutics Co., Ltd. · Beijing · NCT07318155

• Best way to fix under‑expanded coronary stents in resistant blockages

  This compares intravascular lithotripsy (IVL) with high‑pressure or specialty balloons to see if IVL opens under‑expanded coronary stents better in people with in‑stent restenosis.

  Recruiting University Hospital, Clermont-Ferrand · Clermont-Ferrand, Auvergne and 1 other locations · NCT07316504

• Multivessel Hybrid Revascularization for Three-Vessel CAD vs Conventional Off-Pump CABG

  This trial tests whether a minimally invasive multivessel hybrid revascularization (LAD and circumflex grafted via a small thoracotomy plus PCI for the RCA) is better than traditional off-pump CABG done through sternotomy in people with three-vessel coronary disease.

  Recruiting at 2 sites Catharina Ziekenhuis Eindhoven · Leuven, Vlaams Brabant and 1 other locations · NCT07314138

• AI facial-photo screening for coronary artery disease in high-risk community members

  This project tests whether an AI algorithm can use a facial photo to screen for coronary artery disease in people with diabetes, high blood pressure, or over age 65.

  Recruiting at 2 sites China National Center for Cardiovascular Diseases · Zhoukou, Henan and 2 other locations · NCT07277686

• Bypass surgery versus stents for people with weak heart pumping and blockages in multiple coronary arteries

  This trial tests whether bypass surgery (CABG) or stents (PCI) lead to better survival, fewer major heart problems, and improved quality of life for adults with reduced left ventricular function (LVEF ≤40%) and multivessel coronary disease.

  Recruiting University Medical Center Groningen · Groningen · NCT07269366

• Monitoring coronary artery plaque progression in people with type 2 diabetes.

  This project will follow adults with type 2 diabetes who already had a coronary CT angiography to see how plaque in their heart arteries changes over time.

  Recruiting Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) · Amsterdam and 1 other locations · NCT07237685

• Very short DAPT after PCI in older adults

  This trial tests whether stopping aspirin after 7 days of dual antiplatelet therapy is as safe and effective as continuing DAPT for 3 to 12 months in people 65 and older who had a PCI with drug-eluting stents.

  Recruiting Phase 3 University Hospital, Caen · Caen · NCT07164859

• Assessing heart disease risk in former NFL players

  This study looks at heart disease risk in retired NFL players by checking their heart health with special scans to see how their past as professional athletes affects them.

  Recruiting HeartFlow, Inc. · Greenwood Village, Colorado · NCT06831409

• Three-vessel ultrasonic flow ratio to predict one-year heart risk in people with coronary artery disease

  This will test if measuring the ultrasonic flow ratio in all three coronary arteries can help predict one-year risk of major heart problems in adults with coronary artery disease who have at least 30% narrowing in each artery.

  Recruiting China National Center for Cardiovascular Diseases · Beijing · NCT06822894

• Registry for assessing QFR analysis in coronary artery disease

  This study is testing if a new method called QFR for checking blood flow in heart arteries can be used effectively by less experienced doctors during routine procedures for patients with coronary artery disease.

  Recruiting Institute for Cardiovascular Diseases Dedinje · Belgrade · NCT06659367

• Post-market follow-up of Coroflex® ISAR NEO coronary stent system

  This study is testing how safe and effective the Coroflex® ISAR NEO stent is for patients who need it in real-life situations.

  Recruiting at 26 sites Fundación EPIC · Aix-en-Provence and 25 other locations · NCT05698732

• Post-market follow-up for the SUPRAFLEX CRUZ stent in patients with coronary artery disease

  This study is testing how well the SUPRAFLEX CRUZ stent works and if it's safe for people with coronary artery disease who are getting treated in real-life hospital settings.

  Recruiting at 21 sites Fundación EPIC · Elche, Alicante and 20 other locations · NCT05617599

Related topics

Quick answers

How many Coronary Artery Disease (CAD) clinical trials are recruiting right now?

39, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 20 countries. The most sites are in China (8 trials), Netherlands (4 trials), Turkey (Türkiye) (4 trials), United Kingdom (4 trials), France (3 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 2, Phase 4: 1, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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