Long-term registry for Korean patients with heart and brain vascular disease
Official title: PRIME (Precision Registry for Integrated Cardio-cerebrovascular Medicine & Evidence)
Run by Samsung Medical Center · NCT07393412 · Data updated 2026-11-12
This project will collect past and ongoing medical records to see if combining them improves prediction of future health outcomes for Korean patients with heart and blood vessel diseases.
Quick facts
| Study type | Observational |
|---|---|
| Sex | All |
| Enrollment | 800000 (estimated) |
| Sponsor | Samsung Medical Center Academic / other |
| Locations | 1 site (Seoul) |
| Status | Recruiting |
| Started | February 2, 2026 |
| Main results expected | November 27, 2026 |
| Study ends | December 31, 2040 |
| Registry record updated | April 28, 2026 |
| Trial ID | NCT07393412 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are patients who have visited Samsung Medical Center for cardiovascular or cerebrovascular disease and can participate in ongoing medical follow-up.
✕Probably not a fit
Patients who do not receive care at Samsung Medical Center, cannot provide follow-up information, or whose conditions are unrelated to heart or brain blood vessel disease are unlikely to benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Samsung Medical Center will build a standardized clinical registry that combines retrospective medical records with prospective follow-up for patients seen with cardiovascular and cerebrovascular conditions. The registry will capture treatments such as standard medical therapy, revascularization procedures, and lifestyle modification alongside clinical outcomes. Patients will be followed over time through existing records and ongoing visits to identify risk factors, disease trajectories, and outcome patterns specific to the Korean population. The resulting large, unified dataset is intended to support better prediction, prevention, and management strategies.
Why it matters
Potential benefit: If successful, the registry could help clinicians predict complications earlier and tailor prevention and treatment for Korean patients with cardiovascular and cerebrovascular disease.
How similar studies have gone: Large cardiovascular and stroke registries elsewhere have improved risk prediction and care patterns, but a comprehensive long-term Korean-focused registry of this scale is relatively limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: A patient who visited Samsung Medical Center due to cardiovascular and cerebrovascular disease. Exclusion Criteria: A patient deemed unable to participate in the study based on the judgment of the medical staff.
Where it's running
-
Samsung Medical Center
Seoul, South Korea Recruiting
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Tailored digital support to cut sedentary time in long-term cardiac rehab
In adults in a long-term cardiac rehabilitation program, this study tests whether a personalized behavioural program with digital tools can reduce daily sitting time.
-
Health for Hungary: Long-term blood and health data collection to study aging and disease onset
This study tests whether routine blood tests plus advanced molecular analyses can help detect the early stages of non-communicable diseases in adults over 40.
-
Inulin Prebiotic for Perimenopausal Women with Overweight or Obesity
This study tests whether 2 weeks of inulin can affect gut and vaginal microbes, heart health, and muscle health in perimenopausal women who are overweight or obese, using a crossover design.
-
Colchicine to see if it reduces coronary artery inflammation in people with HIV
This study tests whether low-dose colchicine can lower inflammation in the coronary arteries of people with HIV who are at high heart-disease risk, compared with a placebo.
-
Transcatheter Tricuspid Valve Replacement for Severe Tricuspid Regurgitation
This trial tests the Laplace TTVR System to see if it safely and effectively treats adults with severe tricuspid regurgitation.
-
A lifetime registry and imaging database for people with heart, kidney, and metabolic conditions
This project will see if creating a long-term clinical and imaging database for adults with heart, kidney, or metabolic conditions can improve prediction of outcomes and guide care.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.