Surface topography and spine damage in radiographic axial spondyloarthritis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a single-centre, cross-sectional observational study enrolling adults with radiographic axial spondyloarthritis. At one visit, researchers collect DIERS Formetric 4D surface topography data alongside standard clinical assessments and radiographs, then analyze the relationship between topographic measures and structural spine damage using mSASSS. The goal is to see if radiation-free surface topography correlates with established radiographic damage and sagittal balance. Data are analyzed with correlation tests and regression adjusting for age and disease duration. No interventional procedures are performed.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age 18 to 65 years
* Diagnosis of radiographic axial spondyloarthritis fulfilling the ASAS criteria, confirmed by radiographic sacroiliitis according to the modified New York criteria
* Able to provide written informed consent and to complete the assessments
* Available lateral cervical and lumbar radiographs obtained within the 12 months preceding the DIERS measurement

Exclusion Criteria:

* Neurological disease affecting balance, posture or gait (for example Parkinson disease, amyotrophic lateral sclerosis, cerebellar or vestibular disorders, history of stroke)
* History of lower extremity joint arthroplasty (hip or knee)
* Orthopaedic conditions affecting posture, balance or gait (ununited fracture, previous spinal or lower extremity surgery)
* Advanced cardiopulmonary disease, active infection or malignancy
* Pregnancy

Where it's running

• Ankara Etlik City Hospital, Department of Physical Medicine and Rehabilitation
  Ankara, Yenimahalle, Turkey (Türkiye) Recruiting

Study contacts

• Principal investigator: Ajda Bal — Professor of Physical Medicine and Rehabilitation
• Study coordinator: Seyma Alkan, MD
• Email: symalkan@gmail.com
• Phone: +90 538 337 97 91

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Fecal microbiota transplantation for treating axial spondyloarthritis

  This study is testing if a treatment using gut bacteria from healthy donors can help people with axial spondyloarthritis who aren't feeling better with their current medications.

  Recruiting Phase 2 University Hospital of North Norway · Tromsø · NCT06451588

• HB0017 Injection safety and PK in low-weight adults at different injection sites

  This early-phase study tests a single subcutaneous HB0017 injection in healthy, low-weight adults and compares how the body processes the drug when injected at different sites.

  Recruiting Phase 1 Huabo Biopharm Co., Ltd. · Hangzhou, Zhejiang · NCT07920861

• RENEW: a digital program to help people with axial spondyloarthritis manage energy and symptoms

  A web-based, peer-led program called RENEW is tested to see if people with axial spondyloarthritis can easily use it, like it, and benefit from it in managing fatigue and symptoms.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT07836374

• Pain patterns in rheumatic diseases: see if pain works differently in patients and healthy people

  This observational study tests how pain is experienced and measured in people with rheumatic diseases compared with healthy volunteers.

  Recruiting National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT07829497

• ExerciseRx app for people with axial spondyloarthritis

  A mobile app called ExerciseRx is tested to see if it helps people with axial spondyloarthritis exercise more regularly and feel better than usual care.

  Recruiting at 2 sites University of Washington · Seattle, Washington and 1 other locations · NCT07642622

• Carotid ultrasound to guide prevention of heart disease in inflammatory rheumatic diseases

  In people with inflammatory rheumatic diseases like RA, PsA, AxSpA, or SLE who are at modest cardiovascular risk, a carotid ultrasound test is used to see if they should start stronger lipid-lowering therapy to prevent heart problems.

  Recruiting at 7 sites Phase 4 Instituto de Investigación Marqués de Valdecilla · Alicante, Alicante and 16 other locations · NCT07611747

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.