Investigating the role of CARD9 in Ankylosing Spondylitis
CARD9 in Ankylosing Spondylitis
This study is looking at how genes and immune cells affect Ankylosing Spondylitis in veterans, with the goal of finding better ways to predict and personalize treatments for this painful condition.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Portland VA Medical Center NIH-funded |
| Lab location | 1 site (Portland, United States) |
| Project ID | NIH-10807453 on NIH RePORTER |
What this research studies
This research focuses on Ankylosing Spondylitis (AS), a painful inflammatory arthritis that affects many veterans. It aims to understand the genetic and molecular factors that contribute to the disease, particularly the role of certain immune cells that produce inflammatory signals. By identifying biomarkers that predict how well patients respond to existing treatments, the research seeks to improve personalized treatment strategies. The study will involve analyzing immune responses and genetic factors in patients with AS to uncover new insights into the disease's mechanisms.
Who could benefit from this research
Good fit: Ideal candidates for this research are veterans diagnosed with Ankylosing Spondylitis who are experiencing chronic pain and inflammation.
Not a fit: Patients who do not have Ankylosing Spondylitis or related inflammatory arthritis conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized treatment options for patients suffering from Ankylosing Spondylitis.
How similar studies have performed: Previous research has shown promise in understanding immune mechanisms in similar autoimmune diseases, suggesting potential for success in this area as well.
Where this research is happening
Portland, United States
- Portland VA Medical Center — Portland, United States (Active)
Researchers
- Principal investigator: Napier, Ruth — Portland VA Medical Center
- Study coordinator: Napier, Ruth
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.