Condition

AIDS clinical trials and research

• 10Clinical trials
• 272NIH research projects
• 5Countries

Newest AIDS clinical trials

All recruiting trials (10)

• Expanding access to depression treatment for adults with HIV to improve mood and viral control.

  This project tests whether giving HIV clinics extra training and support helps more adults with HIV and depression start proven depression treatments and reach viral suppression within a year.

  Recruiting University of Miami · Cape Town · NCT07032363

• Collaborative care program for young Black and Latino men at risk for HIV

  This study tests a new support program to help young Black and Latino men at risk for HIV start taking prevention medication and manage their substance use better.

  Recruiting Children's Hospital of Philadelphia · Baltimore, Maryland and 1 other locations · NCT06585631

• Financial and counseling support for transgender women to improve health services access

  This study tests whether financial help and personalized counseling can make it easier for transgender women to access substance use services and HIV prevention methods like PrEP.

  Recruiting University of Central Florida · Orlando, Florida · NCT06202898

• Using advanced sequencing to guide infection treatment in AIDS patients

  This study is testing if a new DNA sequencing method can help doctors choose better infection treatments for AIDS patients with severe pneumonia or sepsis compared to standard methods.

  Recruiting Guangzhou 8th People's Hospital · Guangzhou, Guangdong · NCT06145841

• Identifying lung function risks in AIDS patients recovering from severe pneumonia

  This study looks at what might affect lung health in people with AIDS who have recovered from severe pneumonia to see how their lungs are doing after they leave the hospital.

  Recruiting Guangzhou 8th People's Hospital · Guangzhou, Guangdong · NCT06137196

• Achieving a functional cure for hepatitis B in patients with HIV and hepatitis B co-infection

  This study is testing if adding interferon to standard HIV treatment can help people who have both HIV and hepatitis B clear the virus from their system.

  Recruiting Guangzhou 8th People's Hospital · Guangzhou, Guangdong · NCT05988879

• Treatment of late-stage AIDS patients using mesenchymal stem cells

  This study is testing if mesenchymal stem cells can help improve the health of people with late-stage AIDS compared to those receiving a placebo.

  Recruiting at 4 sites Phase 1/2 Cell Energy Life Sciences Group Co. LTD · Beijing and 3 other locations · NCT05939167

• Screening for hepatitis B, hepatitis C and HIV using a dried blood spot

  This project will try a simple dried blood spot test to check people who use drugs for hepatitis B, hepatitis C and HIV.

  Recruiting at 11 sites University Hospital, Rouen · Avranches and 10 other locations · NCT05390424

• Evaluating management strategies for HIV treatment failure in Sub-Saharan Africa

  This study is testing different treatment options for people with HIV in Uganda and South Africa who aren't responding well to their current medication, to see which approach helps them lower their viral load the best.

  Recruiting at 3 sites Massachusetts General Hospital · Durban and 2 other locations · NCT05373758

• Creating a city-wide cohort of HIV-infected individuals in Washington, DC

  This study is creating a big database of people living with HIV in Washington, DC, to help improve their care and health outcomes by collecting and sharing important information from different clinics.

  Recruiting at 14 sites George Washington University · Washington D.C., District of Columbia and 13 other locations · NCT01206920

NIH-funded research (newest 40 of 272)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• An integrated mobile health program to reduce SAVA and mental health problems among female sex workers in Kenya

  A new mobile health program aims to help female sex workers in Kenya avoid substance abuse, violence, HIV, and depression by delivering group therapy, online resources, and a peer discussion space.

  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11625516

• New thin, flexible tactile displays to make screens accessible for people who are blind

  A new thin film technology will let touch-based screens mimic visual displays, helping people who are blind or visually impaired use phones and other devices.

  NIH research University of Delaware · Newark, UNITED STATES · NIH-11609398

• FIOCRUZ HIV/AIDS Clinical Trials Unit: advancing HIV prevention and treatment in Brazil

  A Brazilian clinical trials unit led by Dr. Beatriz Grinsztejn is testing and speeding up new HIV prevention and treatment strategies to help people living with HIV/AIDS and those at risk.

  NIH research Fundacao Oswaldo Cruz · Rio de Janeiro, BRAZIL · NIH-11601065

• Breeding colony expansion to support HIV/AIDS research with rhesus macaques

  A funding opportunity to expand a specialized Rhesus macaque breeding population to support HIV/AIDS research at Tulane’s primate facility.

  NIH research Tulane University of Louisiana · New Orleans, United States · NIH-11581742

• HIV Resilience Observatory in a rhesus macaque colony expansion

  A program to build a rhesus macaque breeding colony and use AI-powered monitoring to study why some HIV/AIDS outcomes differ among individuals with similar backgrounds.

  NIH research Tulane University of Louisiana · New Orleans, United States · NIH-11581712

• Indoor-Outdoor Housing Expansion to Support HIV/AIDS-Related Research

  A HIV-focused project at a primate research center will use new indoor/outdoor housing and AI-assisted monitoring to study why people with similar backgrounds can have very different HIV outcomes.

  NIH research Tulane University of Louisiana · New Orleans, United States · NIH-11581704

• Hearing changes in people with HIV and in people without HIV in Tanzania

  This project follows people living with HIV and similar individuals in Tanzania to see how hearing and brain function relate over time and whether hearing tests can help predict cognitive changes.

  NIH research Dartmouth College · Hanover, United States · NIH-11575474

• ALIVE study: following and helping people who inject drugs with HIV and related health needs

  A Johns Hopkins-led project continues long-term research with people who inject drugs to understand HIV, other health problems, and ways to improve care and well‑being.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11572429

• HIV care and treatment in East Africa: understanding how people stay in care and achieve viral suppression

  A regional effort in East Africa uses health data and smart analysis to understand what helps people living with HIV stay in care and maintain viral suppression amid changing global funding.

  NIH research Indiana University Indianapolis · Indianapolis, United States · NIH-11564005

• East Africa AIDS care and outcomes database: regional insights for treatment and retention

  A regional program in East Africa uses health data to understand how people stay in HIV care and keep viral loads low, even as funding and health systems change.

  NIH research Indiana University Indianapolis · Indianapolis, United States · NIH-11564003

• East Africa HIV care and treatment outcomes study

  This project looks at how people living with HIV in East Africa stay in care, adhere to treatment, and achieve viral suppression over time.

  NIH research Indiana University Indianapolis · Indianapolis, United States · NIH-11564002

• East Africa HIV Care and Treatment Insights Across Regions

  A regional collaboration is extending its work to understand how people in East Africa stay in HIV care and achieve viral suppression as funding and programs change.

  NIH research Indiana University Indianapolis · Indianapolis, United States · NIH-11564001

• East Africa AIDS care: how people living with HIV stay in treatment and reach viral suppression

  A kidney-friendly plain-English description of a study in East Africa to learn why people on HIV treatment stay in care or drop out and how to improve long-term viral suppression.

  NIH research Indiana University Indianapolis · Indianapolis, United States · NIH-11564000

• HIV care and treatment in East Africa: understanding retention and outcomes

  This project looks at how people living with HIV in East Africa stay in care and achieve viral suppression, and how patient development and broader health systems affect outcomes.

  NIH research Indiana University Indianapolis · Indianapolis, United States · NIH-11563999

• Bridging clinic and community care for HIV-positive women facing abuse

  A program will adapt and use an evidence-based approach called CUES to help women living with HIV who experience intimate partner violence get better HIV and mental health outcomes by coordinating care with community organizations.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11563817

• Broadly neutralizing nanobodies to improve HIV therapy

  Researchers are developing tiny antibodies called nanobodies to target HIV in new ways that could make treatments easier and more effective for people living with HIV.

  NIH research Wistar Institute · Philadelphia, United States · NIH-11553145

• Columbia HIV/AIDS Clinical Trials Unit focuses on advancing prevention and treatment in NYC

  A patient-facing CTU in NYC coordinates clinical trials to improve HIV prevention and care for people living with HIV and those at risk.

  NIH research Columbia University Health Sciences · New York, United States · NIH-11540397

• Improving Diagnostics and Neurocognitive Outcomes in HIV/AIDS-related Meningitis

  A study in Uganda aims to use faster, better tests and a new antifungal to help people with HIV who develop meningitis.

  NIH research University of Minnesota · Minneapolis, United States · NIH-11539368

• IeDEA Southern Africa: Big-picture HIV/TB epidemiology and care

  A large international effort studies how HIV, TB, and related health issues affect people in Southern Africa to improve care, prevention, and outcomes.

  NIH research Universitat Bern · Bern, SWITZERLAND · NIH-11539122

• IeDEA Southern Africa: tracking HIV, TB, and related health in the region

  A large international effort collects and analyzes health data from people with HIV in Southern Africa to improve care and outcomes.

  NIH research Universitat Bern · Bern, SWITZERLAND · NIH-11539121

• HIV and TB Epidemiology in Southern Africa: A BIG Data Study

  A long-running international effort uses big health data from Southern Africa to understand how HIV, TB, and related conditions affect people across ages, including pregnant women, children, and adults.

  NIH research Universitat Bern · Bern, SWITZERLAND · NIH-11539120

• IeDEA Southern Africa HIV and TB Epidemiology Network

  A large international effort uses data from Southern Africa to understand how HIV, TB, and related conditions affect people across different ages.

  NIH research Universitat Bern · Bern, SWITZERLAND · NIH-11539119

• Toward ending pediatric HIV: modeling how maternal and infant care can prevent transmission

  A research project uses computer models to figure out the most effective ways to prevent HIV transmission from mothers to their babies and keep kids healthy.

  NIH research Massachusetts General Hospital · Boston, United States · NIH-11538869

• Bridges2Scale: Testing ways to implement an economic program for youths affected by AIDS

  A project tests how well a proven economic-empowerment program can be rolled out to help adolescents and young people affected by HIV in sub-Saharan Africa improve their health, stay on ART, and reduce risky behaviors.

  NIH research New York University · New York, United States · NIH-11535770

• Ending Tobacco Use with a Smartphone Program for Cambodian People Living with HIV/AIDS

  A smartphone-based quit-smoking program designed for people living with HIV/AIDS in Cambodia to help reduce tobacco use alongside HIV treatment.

  NIH research H. Lee Moffitt Cancer Ctr & Res Inst · Tampa, United States · NIH-11535291

• Adolescent HIV Care: Weight Loss Pill + Digital Counseling Trial

  A youth-focused trial tests whether adding a weekly semaglutide weight-loss medicine to tailored digital lifestyle coaching helps overweight teens and young adults living with HIV improve weight and heart health.

  NIH research Florida State University · Tallahassee, United States · NIH-11530515

• Central Africa HIV epidemiology databases to inform AIDS care

  A multi-country project uses a large HIV care database in sub-Saharan Africa to find practical ways to prevent new infections and improve care and to study HIV-related illnesses.

  NIH research Albert Einstein College of Medicine · Bronx, United States · NIH-11528608

• Central Africa AIDS Data Network to Improve Care and Prevention

  A regional HIV care and research program in sub-Saharan Africa is building and linking large patient databases to improve prevention, treatment, and management of HIV and related conditions.

  NIH research Albert Einstein College of Medicine · Bronx, United States · NIH-11528607

• Central Africa AIDS data network to improve HIV care across the region

  A regional network of African and international researchers uses patient data to improve HIV care, prevention, and treatment outcomes for people in sub-Saharan Africa.

  NIH research Albert Einstein College of Medicine · Bronx, United States · NIH-11528606

• Central Africa HIV Data Network to Improve Care Across Sub-Saharan Africa

  A large collaborative database project uses HIV care data from several African countries to improve prevention, treatment, and management of HIV and related health conditions.

  NIH research Albert Einstein College of Medicine · Bronx, United States · NIH-11528605

• Central Africa AIDS data networks to improve care and prevention

  A regional database project uses HIV care data from several African countries to inform better prevention, treatment, and care for people living with HIV.

  NIH research Albert Einstein College of Medicine · Bronx, United States · NIH-11528604

• Bridges2Scale: Testing ways to spread an economic program to help youths affected by AIDS

  A study in sub-Saharan Africa tests if an economic empowerment program for young people affected by HIV improves health and adherence to HIV care.

  NIH research New York University · New York, United States · NIH-11525321

• HIV laboratory support network

  This program runs advanced lab testing and training to help develop and improve treatments for people living with HIV.

  NIH research University of California Los Angeles · Los Angeles, United States · NIH-11524690

• Collaboratory advancing HIV cure research to eradicate persistent infection

  A national team is pursuing new ways to cure HIV by waking up latent virus and helping the body clear infected cells, with the goal of eradicating persistent infection.

  NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-11515081

• Aiming to Cure HIV by Boosting Early Immune Response and Clearing Hidden Cells

  Researchers are testing a combination approach in people to reduce hidden HIV reservoirs while ART is ongoing and to help control the virus if treatment is stopped.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11515078

• Aging-Era HIV Care in East Africa: Tracking Retention and Outcomes

  A long-running project uses East Africa data to understand how people stay in HIV care and achieve viral suppression as funding and health systems change.

  NIH research Indiana University Indianapolis · Indianapolis, United States · NIH-11515073

• Central Africa AIDS data network to improve care across Sub-Saharan Africa

  A regional database project uses real-world HIV care information from multiple African countries to improve prevention, treatment, and health outcomes for people living with HIV.

  NIH research Albert Einstein College of Medicine · Bronx, United States · NIH-11515072

• NAACCORD: North American HIV Cohort Collaboration for Design and Research

  A large network of HIV cohorts in the US and Canada works together to study how HIV affects people over time and how care can be improved.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11515070

• IeDEA Southern Africa: tracking HIV, TB, and health outcomes across the region

  A large international study collects and analyzes HIV and related health data from Southern Africa to understand how people live with HIV, TB, and other health conditions.

  NIH research Universitat Bern · Bern, SWITZERLAND · NIH-11515069

• Bridges2Scale: Testing how to spread an economic empowerment program for teens affected by AIDS

  A 2-year project in Sub-Saharan Africa tests how to scale an economic empowerment program to help adolescents and young people affected by HIV improve their health, finances, and well-being.

  NIH research New York University · New York, United States · NIH-11484457

Related topics

Quick answers

How many AIDS clinical trials are recruiting right now?

10, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 5 countries. The most sites are in China (4 trials), United States (3 trials), South Africa (2 trials), France (1 trial), Uganda (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

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