Creating a city-wide cohort of HIV-infected individuals in Washington, DC
Development of a City-Wide Cohort of HIV-Infected Persons in Care in the District of Columbia: The DC Cohort
This study is creating a big database of people living with HIV in Washington, DC, to help improve their care and health outcomes by collecting and sharing important information from different clinics.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 19000 (estimated) |
| Sex | All |
| Sponsor | George Washington University Academic / other |
| Locations | 14 sites (Washington D.C., District of Columbia and 13 other locations) |
| Trial ID | NCT01206920 on ClinicalTrials.gov |
What this trial studies
The DC Cohort aims to establish a comprehensive, clinic-based longitudinal database of HIV-infected individuals receiving care in Washington, DC. This initiative will involve major community and academic clinics, collecting data on socio-demographics, risk factors, treatments, diagnoses, and clinical outcomes. The cohort will facilitate routine reporting and analytic support to improve the quality of care and clinical outcomes for patients with HIV/AIDS. By comparing data across various clinics, the project seeks to enhance understanding and management of HIV in the region.
Who should consider this trial
Good fit: Ideal candidates for this cohort are individuals aged 18 and older receiving care for HIV at participating clinics in Washington, DC.
Not a fit: Patients who are unable or refuse to provide informed consent, or minors unaware of their HIV status, may not benefit from this cohort.
Why it matters
Potential benefit: If successful, this cohort could significantly improve the quality of care and clinical outcomes for HIV-infected patients in Washington, DC.
How similar studies have performed: Other studies have successfully established similar cohorts, indicating that this approach is both tested and valuable for improving HIV care.
Eligibility criteria
Show full inclusion / exclusion criteria
Treatment Cohort Inclusion Criteria: * Patient is receiving care for HIV at one or more of the twelve participating clinics in the DC Cohort. * Patient is either age 18 years or older, or seeks HIV care independently and is able to understand and sign informed consent. * Patient is a minor who is consented by a parent or legal guardian. Treatment Cohort Exclusion Criteria: * Patient is unable or refuses to provide informed consent. * Minor children ages 12 through 17 who are unaware of their HIV status Prevention Cohort Inclusion Criteria: Persons receiving any antiretroviral prescription without evidence of HIV or Hepatitis B infection * PrEP (e.g., TDF/FTC, Descovy, Apretude) * Combination ART indicative of nPEP in an HIV-uninfected person * Persons receiving an antiretroviral prescription indicative of DoxyPEP Doxycycline 200mg PO taken within 72 hrs of unprotected sexual encounter (or variations thereof where clearly not prescribed as a treatment course) * Test positive for ≥1 bacterial STI (positive gonorrhea (GC/NG) or chlamydia (CT) test or positive syphilis test requiring treatment within one year) * 2 bacterial STI (GC, chlamydia, syphilis) tests at 2 or more different encounters * 2 HIV tests at 2 or more different encounters * Patient requesting PrEP at their clinical visit * Patient requesting nPEP at their clinical visit * People who identify as injecting drugs Patients with a Z29.81 Encounter for HIV pre-exposure prophylaxis
Where this trial is running
Washington D.C., District of Columbia and 13 other locations
- Kaiser Permanente Mid-Atlantic States — Washington D.C., District of Columbia, United States (Recruiting)
- Unity Health Care — Washington D.C., District of Columbia, United States (Recruiting)
- Georgetown University — Washington D.C., District of Columbia, United States (Recruiting)
- La Clinica Del Pueblo — Washington D.C., District of Columbia, United States (Recruiting)
- Whitman-Walker Health — Washington D.C., District of Columbia, United States (Recruiting)
- Children's National Medical Center--Pediatric Clinic — Washington D.C., District of Columbia, United States (Recruiting)
- Washington Hospital Center — Washington D.C., District of Columbia, United States (Recruiting)
- Washington Health Institute — Washington D.C., District of Columbia, United States (Recruiting)
- Family and Medical Counseling Service — Washington D.C., District of Columbia, United States (Recruiting)
- George Washington Medical Faculty Associates — Washington D.C., District of Columbia, United States (Recruiting)
- Howard University Hospital--Adult Clinic — Washington D.C., District of Columbia, United States (Recruiting)
- Howard University Hospital--Pediatric Clinic — Washington D.C., District of Columbia, United States (Recruiting)
- Veterans Affairs Medical Center — Washington D.C., District of Columbia, United States (Recruiting)
- Us Helping Us, People into Living, Inc. — Washington D.C., District of Columbia, United States (Recruiting)
Study contacts
- Principal investigator: Amanda D Castel, MD, MPH — George Washington University
- Study coordinator: Amanda D Castel, MD, MPH
- Email: acastel@gwu.edu
- Phone: 202-994-8325
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.