Creating a city-wide cohort of HIV-infected individuals in Washington, DC

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The DC Cohort aims to establish a comprehensive, clinic-based longitudinal database of HIV-infected individuals receiving care in Washington, DC. This initiative will involve major community and academic clinics, collecting data on socio-demographics, risk factors, treatments, diagnoses, and clinical outcomes. The cohort will facilitate routine reporting and analytic support to improve the quality of care and clinical outcomes for patients with HIV/AIDS. By comparing data across various clinics, the project seeks to enhance understanding and management of HIV in the region.

Why it matters

Who can join: the full rules

Treatment Cohort Inclusion Criteria:

* Patient is receiving care for HIV at one or more of the twelve participating clinics in the DC Cohort.
* Patient is either age 18 years or older, or seeks HIV care independently and is able to understand and sign informed consent.
* Patient is a minor who is consented by a parent or legal guardian.

Treatment Cohort Exclusion Criteria:

* Patient is unable or refuses to provide informed consent.
* Minor children ages 12 through 17 who are unaware of their HIV status

Prevention Cohort Inclusion Criteria:

Persons receiving any antiretroviral prescription without evidence of HIV or Hepatitis B infection

* PrEP (e.g., TDF/FTC, Descovy, Apretude)
* Combination ART indicative of nPEP in an HIV-uninfected person
* Persons receiving an antiretroviral prescription indicative of DoxyPEP Doxycycline 200mg PO taken within 72 hrs of unprotected sexual encounter (or variations thereof where clearly not prescribed as a treatment course)
* Test positive for ≥1 bacterial STI (positive gonorrhea (GC/NG) or chlamydia (CT) test or positive syphilis test requiring treatment within one year)

  * 2 bacterial STI (GC, chlamydia, syphilis) tests at 2 or more different encounters
  * 2 HIV tests at 2 or more different encounters
* Patient requesting PrEP at their clinical visit
* Patient requesting nPEP at their clinical visit
* People who identify as injecting drugs

Patients with a Z29.81 Encounter for HIV pre-exposure prophylaxis

Where it's running

• Kaiser Permanente Mid-Atlantic States
  Washington D.C., District of Columbia, United States Recruiting
• Unity Health Care
  Washington D.C., District of Columbia, United States Recruiting
• Georgetown University
  Washington D.C., District of Columbia, United States Recruiting
• La Clinica Del Pueblo
  Washington D.C., District of Columbia, United States Recruiting
• Whitman-Walker Health
  Washington D.C., District of Columbia, United States Recruiting
• Children's National Medical Center--Pediatric Clinic
  Washington D.C., District of Columbia, United States Recruiting

Study contacts

• Principal investigator: Amanda D Castel, MD, MPH — George Washington University
• Study coordinator: Amanda D Castel, MD, MPH
• Email: acastel@gwu.edu
• Phone: 202-994-8325

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.