Identifying lung function risks in AIDS patients recovering from severe pneumonia

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to identify risk factors associated with lung function impairment in patients who have recovered from severe pneumonia related to AIDS. It involves monitoring lung function at various intervals post-discharge and collecting demographic, clinical, and laboratory data to analyze predictors of lung function decline. The study employs multifactorial logistic regression analysis to assess the relationship between these factors and lung function outcomes over time.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Confirmed HIV infection;
2. Progression to the AIDS stage: CD4+ count \<200 cells/µL and/or occurrence of opportunistic infections associated with AIDS;
3. Age between 18 to 65 years;
4. Meet the diagnostic criteria for severe pneumonia, with reference to the 2021 treatment guidelines for community-acquired pneumonia developed by the American Thoracic Society (ATS) and the Infectious Diseases Society of America (IDSA).

Exclusion Criteria:

1. Concurrent central nervous system lesions, severe liver disease, or cirrhosis;
2. Concurrent AIDS-related or non-related tumors;
3. Women who are pregnant or breastfeeding;
4. Presence of serious underlying diseases such as heart, lung, liver, kidney, etc.;
5. Alcohol abuse or drug use;
6. The researcher believes that the overall condition of the subject affects the evaluation and completion of the trial

Where it's running

• Guangzhou Eighth People's Hospital, Guangzhou Medical University
  Guangzhou, Guangdong, China Recruiting

Study contacts

• Study coordinator: Linghua Li, PhD
• Email: llheliza@126.com
• Phone: +862083710825

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.