Identifying lung function risks in AIDS patients recovering from severe pneumonia
Study on Risk Identification Factors for Lung Function Impairment in AIDS Patients Recovered From Severe Pneumonia
This study looks at what might affect lung health in people with AIDS who have recovered from severe pneumonia to see how their lungs are doing after they leave the hospital.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Sponsor | Guangzhou 8th People's Hospital Academic / other |
| Locations | 1 site (Guangzhou, Guangdong) |
| Trial ID | NCT06137196 on ClinicalTrials.gov |
What this trial studies
This observational study aims to identify risk factors associated with lung function impairment in patients who have recovered from severe pneumonia related to AIDS. It involves monitoring lung function at various intervals post-discharge and collecting demographic, clinical, and laboratory data to analyze predictors of lung function decline. The study employs multifactorial logistic regression analysis to assess the relationship between these factors and lung function outcomes over time.
Who should consider this trial
Good fit: Ideal candidates include adults aged 18 to 65 with confirmed HIV infection and progression to AIDS, who have been diagnosed with severe pneumonia.
Not a fit: Patients with concurrent severe underlying diseases or those with central nervous system lesions may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to early identification and intervention strategies for lung function impairment in AIDS patients recovering from severe pneumonia.
How similar studies have performed: While similar studies have explored lung function in pneumonia patients, this specific focus on AIDS-related cases is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Confirmed HIV infection; 2. Progression to the AIDS stage: CD4+ count \<200 cells/µL and/or occurrence of opportunistic infections associated with AIDS; 3. Age between 18 to 65 years; 4. Meet the diagnostic criteria for severe pneumonia, with reference to the 2021 treatment guidelines for community-acquired pneumonia developed by the American Thoracic Society (ATS) and the Infectious Diseases Society of America (IDSA). Exclusion Criteria: 1. Concurrent central nervous system lesions, severe liver disease, or cirrhosis; 2. Concurrent AIDS-related or non-related tumors; 3. Women who are pregnant or breastfeeding; 4. Presence of serious underlying diseases such as heart, lung, liver, kidney, etc.; 5. Alcohol abuse or drug use; 6. The researcher believes that the overall condition of the subject affects the evaluation and completion of the trial
Where this trial is running
Guangzhou, Guangdong
- Guangzhou Eighth People's Hospital, Guangzhou Medical University — Guangzhou, Guangdong, China (Recruiting)
Study contacts
- Study coordinator: Linghua Li, PhD
- Email: llheliza@126.com
- Phone: +862083710825
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.