NIH-funded research U01 cooperative agreement

HIV care and treatment in East Africa: understanding how people stay in care and achieve viral suppression

Official title: East Africa International Epidemiology Database to evaluate AIDS (IeDEA) Regional Consortium

Funded at Indiana University Indianapolis · NIH-11564005 · Data updated 2026-11-12

A regional effort in East Africa uses health data and smart analysis to understand what helps people living with HIV stay in care and maintain viral suppression amid changing global funding.

More AIDS research and trials

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionIndiana University Indianapolis
NIH-funded
Lab location1 site (Indianapolis, United States)
Project startAugust 5, 2006
Project endJune 30, 2028
Funding year2026
Award (this year)$47,470
NIH project number3U01AI069911-21S6
Project IDNIH-11564005 on NIH RePORTER

Who could benefit from this research

Could help

People living with HIV in the East Africa region who are navigating care and treatment programs, including those with TB coinfection and those at various developmental stages.

Less likely to help

Individuals not engaged in HIV care programs or in regions outside the study scope may not directly benefit.

What this research studies

This project analyzes large, harmonized HIV treatment data from East Africa to identify factors in individuals, health systems, and communities that influence staying in care and achieving viral suppression. It applies modern machine-learning methods to uncover patterns and test how changes in donor funding affect care trajectories. The work builds on strong collaborations with local HIV programs to describe the care cascade and outcomes, including the impact of developmental and behavioral factors. A focus is also placed on the health outcomes of people diagnosed with tuberculosis and how to address barriers to care in that subgroup. The extension aims to generate evidence that can guide policies and programs toward better retention and treatment success.

Why it matters

Potential benefit: If successful, the project could inform strategies to improve retention in HIV care and viral suppression, shaping policies and programs in East Africa and beyond.

How similar studies have gone: Prior regional analyses with harmonized data and advanced analytics have yielded actionable insights for improving retention and outcomes in HIV care.

Where this research is happening

  • Indiana University Indianapolis
    Indianapolis, United States
    Active

Researchers

  • Principal investigator: Wools-Kaloustian, Kara Kay — Indiana University Indianapolis
  • Study coordinator: Wools-Kaloustian, Kara Kay

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.