Toward ending pediatric HIV: modeling how maternal and infant care can prevent transmission
Official title: Reaching for the end of pediatric AIDS: Modeling strategies to strengthen the maternal-child HIV care continuum and eliminate vertical HIV transmission.
Funded at Massachusetts General Hospital · NIH-11538869 · Data updated 2026-11-12
A research project uses computer models to figure out the most effective ways to prevent HIV transmission from mothers to their babies and keep kids healthy.
Quick facts
| Grant type | R37 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | July 1, 2014 |
| Project end | April 30, 2029 |
| Funding year | 2026 |
| Award (this year) | $49,280 |
| NIH project number | 3R37HD079214-13S3 |
| Project ID | NIH-11538869 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are pregnant or lactating women with HIV and their infants, or populations at risk of HIV exposure where maternal interventions could prevent transmission.
✕Less likely to help
Individuals not affected by HIV or not involved in maternal-infant HIV care may not directly benefit.
What this research studies
This project builds and uses a detailed computer model to simulate HIV in children and their mothers in several countries. It analyses how different maternal and infant interventions could reduce infant infections and improve care for mothers with HIV. The aim is to identify strategies that provide the best health benefits and value, guiding policies and programs that protect children from HIV. The work complements real-world data and guidelines to accelerate progress toward ending pediatric HIV.
Why it matters
Potential benefit: If successful, the work could inform smarter policies and interventions that prevent mother-to-child HIV transmission and improve care for HIV-exposed infants and mothers.
How similar studies have gone: Previous CEPAC model work has influenced WHO guidelines and informed policy decisions; this project extends those analyses.
Where this research is happening
-
Massachusetts General Hospital
Boston, United States Active
Researchers
- Principal investigator: Ciaranello, Andrea Lynne — Massachusetts General Hospital
- Study coordinator: Ciaranello, Andrea Lynne
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.