NIH-funded research U01 cooperative agreement

East Africa HIV care and treatment outcomes study

Official title: East Africa International Epidemiology Database to evaluate AIDS (IeDEA) Regional Consortium

Funded at Indiana University Indianapolis · NIH-11564002 · Data updated 2026-11-12

This project looks at how people living with HIV in East Africa stay in care, adhere to treatment, and achieve viral suppression over time.

More AIDS research and trials

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionIndiana University Indianapolis
NIH-funded
Lab location1 site (Indianapolis, United States)
Project startAugust 5, 2006
Project endJune 30, 2028
Funding year2026
Award (this year)$549,168
NIH project number3U01AI069911-21S4
Project IDNIH-11564002 on NIH RePORTER

Who could benefit from this research

Could help

Individuals living with HIV in East Africa who are engaged in or eligible for HIV care programs and who may be affected by care-delivery and funding-context factors.

Less likely to help

Patients not connected to HIV care programs or in contexts outside East Africa may see limited direct benefit.

What this research studies

This grant analyzes large patient data from HIV programs in East Africa to understand what helps people stay in care and keep their virus under control. It uses machine learning and harmonized regional data to identify factors in patients, clinics, and the broader environment that push retention and treatment success. The work continues two main aims: describe how people move through care and what environment factors influence retention, and examine the role of developmental stage and behavior on outcomes. It also focuses on outcomes for people diagnosed with tuberculosis to identify barriers and opportunities for better care. The findings could inform strategies for sustaining HIV care amid changing donor funding and health system contexts.

Why it matters

Potential benefit: If successful, the project could guide policies and programs to improve retention in HIV care and viral suppression in East Africa, potentially reducing AIDS-related morbidity and mortality.

How similar studies have gone: Previous similar analyses have shown that program and environment factors can significantly influence retention and viral suppression.

Where this research is happening

  • Indiana University Indianapolis
    Indianapolis, United States
    Active

Researchers

  • Principal investigator: Wools-Kaloustian, Kara Kay — Indiana University Indianapolis
  • Study coordinator: Wools-Kaloustian, Kara Kay

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.