NIH-funded research U01 cooperative agreement

East Africa AIDS care: how people living with HIV stay in treatment and reach viral suppression

Official title: East Africa International Epidemiology Database to evaluate AIDS (IeDEA) Regional Consortium

Funded at Indiana University Indianapolis · NIH-11564000 · Data updated 2026-11-12

A kidney-friendly plain-English description of a study in East Africa to learn why people on HIV treatment stay in care or drop out and how to improve long-term viral suppression.

More AIDS research and trials

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionIndiana University Indianapolis
NIH-funded
Lab location1 site (Indianapolis, United States)
Project startAugust 5, 2006
Project endJune 30, 2028
Funding year2026
Award (this year)$114,828
NIH project number3U01AI069911-21S2
Project IDNIH-11564000 on NIH RePORTER

Who could benefit from this research

Could help

People living with HIV in East Africa who are enrolled in care programs and whose care pathways can be analyzed for retention and viral suppression.

Less likely to help

Individuals not connected to HIV care programs or whose data are not part of the analyzed cohorts may not directly benefit.

What this research studies

This project looks at how individual factors (like age, health, and behavior), healthcare systems, and the wider environment affect people living with HIV as they stay in care and aim for viral suppression. It will use existing programs in East Africa and apply machine-learning methods to identify which factors help or hinder people at different developmental stages. The researchers plan to describe how people move through care, what environmental changes influence retention, and how TB co-infection affects outcomes. The two-year extension will build on prior work to answer these practical questions for policy makers and clinicians.

Why it matters

Potential benefit: If successful, the project could inform strategies to keep people in HIV care longer and achieve better viral suppression, improving public health outcomes.

How similar studies have gone: Previous IeDEA work has shown that care retention and treatment outcomes are influenced by multiple factors, with machine-learning approaches offering new insights.

Where this research is happening

  • Indiana University Indianapolis
    Indianapolis, United States
    Active

Researchers

  • Principal investigator: Wools-Kaloustian, Kara Kay — Indiana University Indianapolis
  • Study coordinator: Wools-Kaloustian, Kara Kay

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.