Sponsor or institution

Clinical trials and research at Virginia Commonwealth University

• 64Clinical trials
• 551NIH research projects
• 8Countries

Newest trials

All recruiting trials (64)

• Understanding how ADT for prostate cancer may raise blood pressure and whether nerves or kidneys are involved

  This study tests whether nervous system or kidney dysfunction contributes to high blood pressure in men receiving androgen deprivation therapy for prostate cancer.

  Recruiting Phase 4 Virginia Commonwealth University · Richmond, Virginia · NCT07848828

• Role of Visual Attention and Environment on Real-World Walking for People With Lower Limb Amputation

  This study tests how vision-based thinking and different walking environments affect real-world gait in people with a leg amputation.

  Recruiting Virginia Commonwealth University · Richmond, Virginia · NCT07831707

• HD-tDCS during CBT for Cocaine Use Disorder

  This study tests whether adding high-definition transcranial direct current stimulation to cognitive behavioral therapy helps adults with cocaine use disorder see if CBT works better.

  Recruiting Virginia Commonwealth University · Richmond, Virginia · NCT07829263

• Metronomic Decitabine-Cedazuridine and Venetoclax therapy for relapsed/refractory AML and high-risk blood cancers

  This phase 2 trial tests a metronomic decitabine-cedazuridine plus venetoclax regimen versus azacitidine plus venetoclax in adults with relapsed/refractory AML or high-risk MDS/MPN.

  Recruiting Phase 2 Virginia Commonwealth University · Richmond, Virginia · NCT07710534

• Impact of Food Help on Adherence to Cancer Treatment

  This study tests whether providing food assistance helps adults with cancer who have food insecurity stick to their treatment plans.

  Recruiting Virginia Commonwealth University · Richmond, Virginia · NCT07706192

• Understanding long-term progression in myotonic dystrophy type 1 (DM1)

  This study will follow adults with DM1 for at least four years to see how walking, hand function, muscle strength, heart rhythms, and lung function change over time.

  Recruiting Virginia Commonwealth University · Richmond, Virginia · NCT07700225

• Single Fraction Partial Breast Irradiation for early breast cancer

  This phase 2 study tests a one-day, multicatheter interstitial partial breast irradiation approach to see if it is safe for women with early breast cancer who have had lumpectomy.

  Recruiting Phase 2 Virginia Commonwealth University · Richmond, Virginia · NCT07654257

• Safety and tolerability testing of VVZ-2471 in healthy adults

  This study tests whether VVZ-2471 is safe and tolerable in healthy adults who don’t use illicit drugs.

  Recruiting Phase 1 Virginia Commonwealth University · Richmond, Virginia · NCT07531316

• Hospital program using virtual reality to prevent firearm violence in injured youth

  This project will test whether a short virtual reality program called Elevate can help prevent firearm-related violence, reinjury, and hospital return among English-speaking teens aged 13–17 treated at VCU.

  Recruiting Virginia Commonwealth University · Richmond, Virginia · NCT07475247

• Integrating a Produce Prescription into a Diabetes Prevention Program

  This study tests whether adding a prescription produce program to a diabetes prevention program helps adults with prediabetes reduce risk factors better than a standard program.

  Recruiting Virginia Commonwealth University · Richmond, Virginia · NCT07472712

• Alveolar ridge preservation after removing upper back molars

  This test compares placing an Ossix mineralized graft immediately after an upper molar extraction versus waiting to graft at implant placement to see if immediate grafting better preserves bone for future dental implants.

  Recruiting Virginia Commonwealth University · Richmond, Virginia · NCT07433322

• Heart health education with VR for breast cancer patients on certain therapies

  This trial tests a virtual reality program to help breast cancer survivors learn about heart health and healthy behaviors while they receive treatments like anthracyclines or trastuzumab.

  Recruiting at 3 sites Virginia Commonwealth University · Richmond, Virginia and 2 other locations · NCT07426913

• Community mobility using walking and wheeled devices after lower limb amputation

  Researchers will use wearable GPS and activity sensors to see how adults with lower limb amputation combine walking and wheeled mobility when they move around their communities.

  Recruiting Virginia Commonwealth University · Richmond, Virginia · NCT07387744

• Cholinergic degeneration and cognitive fluctuations in Lewy body dementias

  This project will test whether loss of cholinergic neurons is linked to cognitive fluctuations in people with Lewy body dementias using blood and skin biomarkers, multimodal MRI, prolonged EEG, and will try an 8‑week galantamine treatment in a small subgroup.

  Recruiting Phase 4 Virginia Commonwealth University · Richmond, Virginia · NCT07284290

• Virtual Housecalls for teens: helping adolescents with obesity in primary care

  A telehealth-based program tests a 6-month intensive lifestyle approach to help adolescents aged 12-15 with class I obesity lose weight, using caregiver support and in-person visits plus virtual coaching.

  Recruiting Virginia Commonwealth University · Henrico, Virginia · NCT07246603

• Cognitive Strategies, Mindfulness & Rehabilitation (C-SMART) versus Brain Health Education and Wellness (BE Well) for adults with brain tumors

  This project will test whether an 8-week individualized telehealth program combining cognitive rehabilitation and mindfulness (C-SMART) helps adults with brain tumors more than an 8-week brain health education video program (BE Well).

  Recruiting Virginia Commonwealth University · Richmond, Virginia · NCT07224503

• Enhancing Addiction Treatment Through Psychoeducation

  A digital program tests whether neuroscience-based psychoeducation plus games can help people with opioid or stimulant use disorders who are on treatment to improve metacognition and treatment engagement.

  Recruiting Virginia Commonwealth University · Richmond, Virginia · NCT07178158

• How two myoelectric control methods affect attention and daily function for people with below-the-elbow amputation

  This project tests whether pattern recognition control or traditional two-site direct myoelectric control is easier to use and more helpful for adults with below-the-elbow (transradial) limb loss when using a prosthesis.

  Recruiting at 2 sites Virginia Commonwealth University · Austin, Texas and 1 other locations · NCT07075042

• Treatment to improve heart rate variability for long-term concussion symptoms

  This trial tests whether a non-invasive heart rate variability biofeedback program can reduce long-term post-concussion symptoms in adults with a history of mild TBI, including veterans and service members.

  Recruiting Phase 2/3 Virginia Commonwealth University · Richmond, Virginia · NCT07071350

• FearLess for adults with malignant brain tumors and their caregivers

  This project will test whether the FearLess psychological program can reduce fear of cancer recurrence in adults with primary malignant brain tumors and their nonprofessional caregivers.

  Recruiting Virginia Commonwealth University · Richmond, Virginia · NCT06989086

• Lemborexant for insomnia in adults with opioid use disorder on buprenorphine

  This trial will see if taking lemborexant each night for 8 weeks improves sleep, mood, and impulsive behavior in adults with moderate opioid use disorder who are stable on buprenorphine.

  Recruiting Phase 2 Virginia Commonwealth University · Richmond, Virginia · NCT06981195

• Twice-daily azelaic acid cream for skin during breast radiation

  This pilot tests if applying azelaic acid cream twice a day before, during, and for several weeks after radiation can reduce skin problems in people getting breast cancer radiation.

  Recruiting Phase 1 Virginia Commonwealth University · Richmond, Virginia · NCT06966388

• Evaluating ways to protect the palate after gum graft removal

  This study is testing different ways to protect the mouth after gum surgery to see which method helps with healing and pain for patients.

  Recruiting Virginia Commonwealth University · Richmond, Virginia · NCT06892496

• Effects of exercise and brain stimulation on anxiety

  This study is testing whether combining cycling exercise with a special brain stimulation can help reduce anxiety in healthy adults.

  Recruiting Virginia Commonwealth University · Richmond, Virginia · NCT06874595

• Single-session intervention to prevent eating disorders

  This study is testing a quick, one-time session to help prevent eating disorders in teenagers who might be at risk.

  Recruiting Virginia Commonwealth University · Richmond, Virginia · NCT06861608

• Zanubrutinib with R-CHOP for DLBCL that has MYD88, CD79B, NOTCH1 changes, or is CD5+

  This study will try adding zanubrutinib to standard R-CHOP chemotherapy for adults with DLBCL who have an MYD88 L265P, CD79B, or NOTCH1 truncation mutation, or who are CD5+ by IHC.

  Recruiting Phase 2 Virginia Commonwealth University · Richmond, Virginia · NCT06846463

• Using Valbenazine with Botulinum Toxin for Cervical Dystonia

  This study is testing if adding a medication called valbenazine to botulinum toxin injections can help people with cervical dystonia feel better and improve their quality of life.

  Recruiting Phase 2 Virginia Commonwealth University · Richmond, Virginia · NCT06771323

• Assessing Readiness and Endpoints for Pediatric Myotonic Dystrophy

  This study is trying to improve how we understand and measure the effects of congenital and childhood myotonic dystrophy to help create better treatments for kids with these conditions.

  Recruiting Virginia Commonwealth University · Little Rock, Arkansas and 3 other locations · NCT06747884

• Reduced chemotherapy and immunotherapy for older adults with advanced lung cancer

  This study is testing a lower dose of chemotherapy combined with immunotherapy to see if it's safe and tolerable for older adults over 70 with advanced lung cancer who can’t have curative treatment.

  Recruiting at 2 sites Phase 2 Virginia Commonwealth University · Richmond, Virginia and 1 other locations · NCT06731413

• Adding antibiotics to chemotherapy for colorectal cancer treatment

  This study is testing if adding antibiotics and aspirin to standard chemotherapy can help people with stage IV colorectal cancer respond better to their first treatment.

  Recruiting at 2 sites Phase 2 Virginia Commonwealth University · Richmond, Virginia and 1 other locations · NCT06728072

• Community-based hydration intervention in schools

  This study is testing a program in schools to see if adding water stations helps students drink more water, stay healthier, and improve their overall well-being.

  Recruiting Virginia Commonwealth University · Henrico, Virginia · NCT06714929

• Comparing an AI chatbot and handouts to boost oral cancer awareness

  This project will test whether an AI-powered chatbot or traditional educational handouts better increase oral cancer knowledge among African American adults in the Richmond area.

  Recruiting Virginia Commonwealth University · Richmond, Virginia · NCT06682494

• GZ17-6.02 treatment for advanced prostate cancer after hormone therapy

  This study is testing a new treatment called GZ17-6.02 to see if it can help men with advanced prostate cancer that hasn't responded to hormone therapy.

  Recruiting Phase 1 Virginia Commonwealth University · Richmond, Virginia · NCT06636123

• Exploring the role of the brain in Postural Orthostatic Tachycardia Syndrome

  This study is trying to see how the brain might be involved in Postural Orthostatic Tachycardia Syndrome (POTS) and how it affects people's symptoms and other health issues over time.

  Recruiting Virginia Commonwealth University · Richmond, Virginia · NCT06616363

• Registry for understanding BK virus in kidney transplant patients

  This study is trying to understand how the immune system responds to BK virus infections in kidney transplant patients to see how different treatments can help manage the virus and prevent complications.

  Recruiting Virginia Commonwealth University · Richmond, Virginia · NCT06538961

• Body, Mind, and Inflammation program for 18–25-year-old women with higher BMI

  This trial will test whether an integrated lifestyle program combining diet, activity, and mental-health strategies helps women aged 18–25 with BMI 25–50 kg/m^2 lose body fat and reduce inflammation more than a standard weight-loss approach over 12 months.

  Recruiting Virginia Commonwealth University · Richmond, Virginia · NCT06532747

• Oral Azacitidine for Transplant-Eligible Patients with Acute Myeloid Leukemia

  This study is testing if an oral medication called azacitidine can help patients with acute myeloid leukemia who are eligible for a transplant and face health challenges stay healthy after treatment.

  Recruiting Phase 4 Virginia Commonwealth University · Richmond, Virginia · NCT06370000

• Virtual reality intervention to prevent gun violence among injured adults

  This study is testing a virtual reality program to see if it can help injured adults make better choices and reduce gun violence in their lives.

  Recruiting Virginia Commonwealth University · Richmond, Virginia · NCT06239285

• Home-based exercise program to lower heart disease risk in prostate cancer patients

  This study is testing whether a home-based exercise program can help improve the fitness and health of prostate cancer patients compared to a group that only receives healthy living tips.

  Recruiting Phase 1/2 Virginia Commonwealth University · Richmond, Virginia and 1 other locations · NCT06237179

• Evaluating heart function during exercise after ablation for atrial fibrillation

  This study is testing how well the heart works during exercise in people who have had a procedure to treat their irregular heartbeat, to see if their ability to exercise improves over time.

  Recruiting Virginia Commonwealth University · Richmond, Virginia · NCT06212791

• Improving rehabilitation care for traumatic brain injury patients with community health services

  This study is testing if adding community health workers to help support people with traumatic brain injury and their families can make their transition from hospital to home easier and improve their recovery.

  Recruiting Early Phase 1 Virginia Commonwealth University · Richmond, Virginia · NCT06188364

• Accelerated radiation treatment for breast cancer

  This study is testing a quicker way to give radiation treatment for breast cancer in patients who have just had surgery to see if it is safe and effective.

  Recruiting Phase 2 Virginia Commonwealth University · Richmond, Virginia · NCT06185205

• Cryospray therapy for treating benign airway stenosis

  This study is testing if adding cryospray therapy to standard treatments can help people with benign airway stenosis avoid having their condition come back within six months.

  Recruiting Phase 1 Virginia Commonwealth University · Richmond, Virginia · NCT06085209

• Improving access to lung cancer screening through patient navigation

  This study tests a patient navigation program to help more people, especially Black or African-American individuals with a certain smoking history, get screened for lung cancer using low dose CT scans.

  Recruiting at 3 sites Virginia Commonwealth University · Carrboro, North Carolina and 2 other locations · NCT06070870

• Observational study on muscular dystrophy outcomes

  This study is tracking up to 1000 people with different types of muscular dystrophy to see how their conditions progress and help develop better treatments in the future.

  Recruiting Virginia Commonwealth University · Richmond, Virginia · NCT05989620

• A tool to help young cancer patients manage their symptoms

  This study is testing a new computer tool to help young cancer patients better manage their symptoms during treatment.

  Recruiting at 4 sites Virginia Commonwealth University · Kansas City, Missouri and 4 other locations · NCT05958316

• Examining how non-invasive neural stimulation affects motor control

  This study tests if using non-invasive brain stimulation can help people with motor difficulties, like those recovering from strokes, improve their movement skills by changing how they receive sensory feedback during tasks.

  Recruiting Virginia Commonwealth University · Richmond, Virginia · NCT05947279

• Understanding research participation among transgender and gender-diverse youth

  This study looks at what helps or stops transgender and gender-diverse youth from joining research projects to make it easier for them to participate in the future.

  Recruiting Virginia Commonwealth University · Richmond, Virginia · NCT05927350

• Online assessment of prewriting skills in children

  This study is testing a new online tool to see how well children aged 3 to 7 can write before they start school, so that those who need help can get it early.

  Recruiting Virginia Commonwealth University · Richmond, Virginia · NCT05905523

• Automated robotic monitoring of blood flow in traumatic brain injury patients

  This study is testing if a new robotic system that monitors blood flow can safely help doctors gather important information about patients with severe brain injuries.

  Recruiting Virginia Commonwealth University · Davis, California and 2 other locations · NCT05848297

• Comprehensive tobacco cessation program for cancer patients, survivors, and caregivers

  This program will try offering gold-standard medications (nicotine replacement, bupropion, or varenicline) plus behavioral counseling to help cancer patients, survivors, and caregivers quit tobacco.

  Recruiting Virginia Commonwealth University · Richmond, Virginia · NCT05805722

• Monitoring liver health in patients with Nonalcoholic Steatohepatitis and cirrhosis

  This study is testing new ways to monitor liver health in people with Nonalcoholic Steatohepatitis and cirrhosis to see if they can better predict complications and improve care.

  Recruiting at 2 sites Virginia Commonwealth University · Rochester, Minnesota and 1 other locations · NCT05720663

• Understanding how the brain communicates in young people with Postural Tachycardia Syndrome

  This study is testing how young people with Postural Tachycardia Syndrome understand visual information to see how their brain communicates differently compared to healthy peers.

  Recruiting Virginia Commonwealth University · Richmond, Virginia · NCT05618054

• Collection of samples from patients with neuromuscular diseases

  This study is collecting blood, skin, and muscle samples from people with neuromuscular diseases to help researchers learn more about these conditions in the future.

  Recruiting Virginia Commonwealth University · Richmond, Virginia · NCT05434572

• Telehealth intervention combining exercise and stimulation for people with tetraplegia

  This study is testing whether a new home-based program that combines special exercises and nerve stimulation can help people with tetraplegia improve their movement and quality of life.

  Recruiting at 3 sites Virginia Commonwealth University · Richmond, Virginia and 2 other locations · NCT05423600

• Assessing clinical endpoints in children with myotonic dystrophy

  This study is trying to find better ways to measure how children with myotonic dystrophy are developing and feeling, so we can understand their condition and improve their care.

  Recruiting at 5 sites Virginia Commonwealth University · Los Angeles, California and 4 other locations · NCT05224778

• Treating heart dysfunction in cancer survivors with a specific medication

  This study is testing if a heart medication called sacubitril-valsartan is safe and helpful for adult cancer survivors under 39 who have early signs of heart failure but no symptoms.

  Recruiting Phase 1/2 Virginia Commonwealth University · Richmond, Virginia · NCT05194111

• Preventing youth violence through hospital-based interventions

  This study is testing a hospital program called Bridging the Gap to see if it can help reduce violence among young people aged 10-17 who have been hurt in violent incidents.

  Recruiting Virginia Commonwealth University · Richmond, Virginia · NCT05078164

• Examining how exercise affects blood vessel function in people with mental health disorders

  This study is testing how different types of exercise can improve blood vessel health in people with mental health disorders like PTSD and anxiety, while also looking at the effects of antioxidant pills.

  Recruiting Virginia Commonwealth University · Richmond, Virginia · NCT04922762

• Examining how exercise affects blood vessel function in people with mental health disorders

  This study is testing how different exercise programs can improve blood vessel health in people with mental health disorders like PTSD and anxiety, as well as in healthy individuals.

  Recruiting Virginia Commonwealth University · Richmond, Virginia · NCT04916340

• Examining how exercise affects blood vessel health in people with mental health disorders

  This study tests how exercise and antioxidant pills can improve blood vessel health in people with mental health disorders like PTSD and GAD, compared to healthy individuals.

  Recruiting Virginia Commonwealth University · Richmond, Virginia · NCT04916327

• Reducing gun violence in injured adults

  This study is testing a hospital program called Bridging the Gap to see if it can help adults who have been injured by violence reduce future violent behavior and improve their overall well-being.

  Recruiting Virginia Commonwealth University · Richmond, Virginia · NCT04813185

• Neoadjuvant therapy and radiation for rectal cancer

  This study is testing a new treatment plan that combines chemotherapy and radiation before surgery to see if it helps people with rectal cancer live longer without the disease coming back.

  Recruiting at 3 sites Phase 2 Virginia Commonwealth University · Richmond, Virginia and 3 other locations · NCT04643366

• Identifying biomarkers and clinical endpoints in Myotonic Dystrophy Type 1

  This study is trying to learn more about Myotonic Dystrophy Type 1 by looking at how the disease affects around 700 adults over two years, including their muscle health and daily activities.

  Recruiting at 15 sites Virginia Commonwealth University · La Jolla, California and 16 other locations · NCT03981575

NIH-funded research (newest 40 of 551)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Healthy Communities for Youth: Preventing Youth Violence in Richmond and Beyond

  A community-centered program to reduce youth violence in Richmond, VA and similar communities by pairing youth voices, hospital-based support, and capacity-building for local groups.

  NIH research Virginia Commonwealth University · Richmond, United States · NIH-11624201

• S1P-S1PR1: How brain cells talk to each other during development

  A study at Virginia Commonwealth University will look at how brain support cells called astrocytes communicate with neurons to shape brain circuits in development.

  NIH research Virginia Commonwealth University · Richmond, United States · NIH-11609332

• Leader cell mechanics drive collective tumor invasion in breast cancer

  A small grant is funding research to understand how leader cancer cells at the edge of a tumor sense their environment and drive groups of cancer cells to invade, which could reveal new ways to stop metastasis in breast cancer.

  NIH research Virginia Commonwealth University · Richmond, United States · NIH-11608538

• How itch-sensing nerves affect skin defense against parasites

  Scientists want to see if itching nerves in the skin influence how the body fights skin-hugging parasites like Schistosoma mansoni.

  NIH research Virginia Commonwealth University · Richmond, United States · NIH-11605896

• VA-ACCERT Center: Transforming Cancer Control in Virginia's public housing communities

  A team at Virginia universities partners with public housing programs to spread proven ways to prevent cancer and improve cancer health in low-income communities.

  NIH research Virginia Commonwealth University · Richmond, United States · NIH-11603149

• PROMINENT cancer research: understanding how mutations in normal tissue relate to cancer growth

  A cancer research project at a major university is exploring how DNA mutations in normal cells relate to the development of cancer, using animal models and human tissues to uncover clues that could inform prevention and treatment.

  NIH research Virginia Commonwealth University · Richmond, United States · NIH-11601741

• Alcohol Use Disorder and Suicidal Behavior: Finding Why They Occur Together

  A study using Swedish population data to understand why alcohol use disorder relates to suicidal thoughts and acts, with the goal of improving risk prediction and prevention.

  NIH research Virginia Commonwealth University · Richmond, United States · NIH-11601596

• Cross-species study of gene networks linked to alcohol-related behaviors

  A large, collaborative effort is exploring how genetic networks related to alcohol use and bipolar disorder are connected across species to better understand why some people with bipolar disorder may be more affected by alcohol use disorders.

  NIH research Virginia Commonwealth University · Richmond, United States · NIH-11596742

• Liver Cirrhosis Network: Centers for Clinical Research

  A multicenter study in people with cirrhosis from different causes (including HIV, NASH, and alcohol-related liver disease) to collect data and samples and test new ways to predict and monitor disease progression.

  NIH research Virginia Commonwealth University · Richmond, United States · NIH-11591517

• Pilot Projects for Patient-Docused Cancer Models (PDX/PDO) Core

  A core at Virginia Commonwealth University will quickly expand the use of patient-derived tumor models to support translational cancer research aimed at reducing cancer burden in patients.

  NIH research Virginia Commonwealth University · Richmond, United States · NIH-11580907

• DYRK1A and facial development: finding the right balance to prevent birth defects

  This project explores how changing levels of the DYRK1A protein affect face formation in embryos and in cells from people with Down syndrome.

  NIH research Virginia Commonwealth University · Richmond, United States · NIH-11576157

• Understanding how HPV16 hijacks human cells to replicate and spread

  A scientist team is studying a key HPV16 protein and its interactions with human cells to find new ways to block the virus that can cause anogenital cancers.

  NIH research Virginia Commonwealth University · Richmond, United States · NIH-11572333

• VCU Massey Cancer Center's Community Cancer Research Network

  A community-focused cancer research program helps people in Virginia access NCI-approved trials and cancer care studies.

  NIH research Virginia Commonwealth University · Richmond, United States · NIH-11543526

• Role of nBMP2 in macrophages to improve gum and bone healing

  A scientist-led project at a university will study how a protein variant in immune cells affects healing of the gums and jawbone, with the aim of improving regeneration in adults.

  NIH research Virginia Commonwealth University · Richmond, United States · NIH-11532999

• TOPOWA: Understanding how social factors affect mental illness in AGYW in Kampala

  A study is testing if targeted socioeconomic training helps 18–24 year-old young women in urban Kampala cope with poverty-related stress and mental health symptoms.

  NIH research Virginia Commonwealth University · Richmond, United States · NIH-11518848

• Risk pathways to major depression using big Danish and Swedish data

  A large study using health and genetic data from Denmark and Sweden will help understand what genetic and environmental factors contribute to major depression across how people grow up.

  NIH research Virginia Commonwealth University · Richmond, United States · NIH-11517264

• Understanding genetic and environmental pathways to major depression in Nordic health records

  A large study will look at how genes and life experiences combine over time to influence major depression, using Danish and Swedish population data.

  NIH research Virginia Commonwealth University · Richmond, United States · NIH-11517263

• Understanding causes of depression, anxiety, and related conditions

  Using long-term health, family, genetic, and gut microbiome data from adults, this project looks for what leads to depression, anxiety, and conditions like chronic fatigue.

  NIH research Virginia Commonwealth University · Richmond, United States · NIH-11514443

• How opioid medications may affect thinking and brain health in people with HIV

  This NIH grant tests whether buprenorphine or methadone have different effects on thinking skills and brain health in a model that mimics HIV.

  NIH research Virginia Commonwealth University · Richmond, United States · NIH-11474460

• Imaging brain inflammation in Alzheimer's with new NLRP3 PET tracers

  New PET imaging tracers that detect NLRP3-related brain inflammation for people with Alzheimer's disease.

  NIH research Virginia Commonwealth University · Richmond, United States · NIH-11457062

• Adaptive design optimization to build quick, reliable behavioral tests for substance use disorders

  A researcher team will test a smarter way to measure thinking, motivation, and emotions in people with substance use issues, using quick, precise tasks.

  NIH research Virginia Commonwealth University · Richmond, United States · NIH-11455249

• Adaptive design-optimized behavioral tasks for substance use disorders

  A new project will use smart, data-driven methods to quickly and reliably measure brain- and behavior-related traits in people with substance use disorders.

  NIH research Virginia Commonwealth University · Richmond, United States · NIH-11455248

• Boosting the effectiveness of TROP2-targeted antibody-drug conjugates in cancer

  A research project tests ways to make approved TROP2-targeting cancer drugs work better in tumors using patient-derived models.

  NIH research Virginia Commonwealth University · Richmond, United States · NIH-11449495

• Targeting PIPKIγi5 to boost immune responses against head and neck cancer

  A study to see if blocking a specific enzyme, PIPKIγi5, can make head and neck cancer more visible to the immune system and more responsive to existing immunotherapies.

  NIH research Virginia Commonwealth University · Richmond, United States · NIH-11449300

• Transforming cancer clinical trials through education, leadership, and community partnerships

  This grant supports expanding patient access to NCI-sponsored cancer trials by empowering Early-Stage Investigators and strengthening community partnerships at a major cancer center.

  NIH research Virginia Commonwealth University · Richmond, United States · NIH-11447171

• Understanding how a specific bacterial enzyme affects Alzheimer’s-related inflammation

  Scientists are studying how a bacterial enzyme in Porphyromonas gingivalis interacts with inflammation that may be linked to Alzheimer’s disease, with potential to inform new ways to protect brain health.

  NIH research Virginia Commonwealth University · Richmond, United States · NIH-11447064

• Molecular clues to bone loss from disuse

  This project looks for genes that influence bone loss when people or animals don’t move much, like during bed rest or spaceflight.

  NIH research Virginia Commonwealth University · Richmond, United States · NIH-11444881

• Spatial map of disease-driving cell networks in Sjögren's disease

  A study to map how disease-causing cells talk to each other in Sjögren's disease and see how this network changes with therapy to guide better treatments.

  NIH research Virginia Commonwealth University · Richmond, United States · NIH-11441996

• HNSCC, iron addiction, and potential iron-targeted therapies

  This grant explores how head and neck cancer cells become dependent on iron and whether targeting iron pathways could lead to new treatments for patients with recurrent or metastatic disease.

  NIH research Virginia Commonwealth University · Richmond, United States · NIH-11441057

• Renal telocytes and Piezo1: how kidney sensors control blood pressure

  Researchers will study a kidney cell type and a pressure sensor protein to understand how the body keeps blood pressure in check.

  NIH research Virginia Commonwealth University · Richmond, United States · NIH-11434495

• CMV vaccine to protect mothers and babies from congenital CMV infections

  A new CMV vaccine approach aims to safely protect pregnant women and their babies from congenital CMV and related birth defects.

  NIH research Virginia Commonwealth University · Richmond, United States · NIH-11433338

• School meal policy changes and how they affect kids’ diets in two states

  This grant studies how new school meal rules in two states change what children eat and their health over several years.

  NIH research Virginia Commonwealth University · Richmond, United States · NIH-11425496

• Gene clues that help DM1 muscle disease age and treatment answers

  A large NIH grant will study how DNA repair and RNA splicing genes influence when DM1 symptoms start and how patients respond to treatments.

  NIH research Virginia Commonwealth University · Richmond, United States · NIH-11423684

• Pediatric Natural History of Myotonic Dystrophy Type 1

  A study following children and young people with this muscular disease to better understand how it progresses over time.

  NIH research Virginia Commonwealth University · Richmond, United States · NIH-11423675

• Shared Resource Core for Myotonic Dystrophy Biomarkers and Biospecimen Access

  A core resource at a major university will make muscle samples, DNA, cell lines, and a key biomarker for myotonic dystrophy more accessible to researchers and patients alike.

  NIH research Virginia Commonwealth University · Richmond, United States · NIH-11423667

• Training support for DM researchers and clinicians to advance muscular dystrophy science

  A training-focused NIH grant helps early-career researchers and clinicians learn how myotonic dystrophy works and how to develop new therapies.

  NIH research Virginia Commonwealth University · Richmond, United States · NIH-11423661

• Administrative Core supporting pediatric therapeutic development for Myotonic Dystrophy

  This NIH grant funds a center core to accelerate therapies for Myotonic Dystrophy, including pediatric considerations and collaboration with patients and industry to move promising ideas toward real treatments.

  NIH research Virginia Commonwealth University · Richmond, United States · NIH-11423654

• Preparing therapies for DM1 across ages, with a focus on children

  A broad, patient-focused effort to bring promising DM1 therapies to both children and adults by enriching trial readiness, biomarkers, and natural history data.

  NIH research Virginia Commonwealth University · Richmond, United States · NIH-11423652

• Community-based hydration program for elementary students

  A school-based program in a Virginia district uses water access and policies to help kids drink more water instead of sugary drinks, aiming to support health and learning.

  NIH research Virginia Commonwealth University · Richmond, United States · NIH-11419204

• Could environmental factors in Central Virginia be linked to ALS clusters

  A study exploring whether local environmental exposures in Central Virginia are connected to clusters of ALS cases and what this could mean for prevention.

  NIH research Virginia Commonwealth University · Richmond, United States · NIH-11418689

Quick answers

How many clinical trials run by Virginia Commonwealth University are recruiting right now?

64, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 8 countries. The most sites are in United States (64 trials), Italy (2 trials), Brazil (1 trial), Canada (1 trial), Germany (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 9, Phase 1: 4, Phase 4: 3, Phase 1/2: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

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