Adaptive design-optimized behavioral tasks for substance use disorders
Official title: Utility of adaptive design optimization for developing rapid and reliable behavioral paradigms for substance use disorders
Funded at Virginia Commonwealth University · NIH-11455248 · Data updated 2026-11-12
A new project will use smart, data-driven methods to quickly and reliably measure brain- and behavior-related traits in people with substance use disorders.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Virginia Commonwealth University NIH-funded |
| Lab location | 1 site (Richmond, United States) |
| Project start | September 1, 2023 |
| Project end | June 30, 2028 |
| Funding year | 2026 |
| Award (this year) | $37,329 |
| NIH project number | 3R01DA058038-04S1 |
| Project ID | NIH-11455248 on NIH RePORTER |
Who could benefit from this research
✓Could help
Individuals with substance use disorders who participate in neurobehavioral assessment sessions.
✕Less likely to help
Patients not undergoing neurobehavioral testing or not fitting the study criteria may not benefit.
What this research studies
This project aims to shorten and improve the way we test thinking, motivation, and emotions related to addiction by applying Bayesian adaptive design optimization to existing tasks. By refining how information is gathered from participants, the study seeks faster, more reliable assessments of the three ANA domains: executive function, incentive salience, and negative emotionality. The approach focuses on reducing participant burden while increasing precision, potentially aiding early biomarker discovery. Results could guide personalized approaches to understanding and treating substance use disorders.
Why it matters
Potential benefit: If successful, patients could benefit from quicker, more accurate assessments that inform tailored treatment plans.
How similar studies have gone: Similar adaptive-design approaches have shown promise in improving measurement precision in cognitive and behavioral assessments.
Where this research is happening
-
Virginia Commonwealth University
Richmond, United States Active
Researchers
- Principal investigator: Vassileva, Jasmin L — Virginia Commonwealth University
- Study coordinator: Vassileva, Jasmin L
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.