Home-based exercise program to lower heart disease risk in prostate cancer patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to evaluate the effectiveness of a home-based exercise training intervention designed to improve exercise capacity in patients diagnosed with prostate cancer. Participants will engage in an exercise program and will be compared to a control group receiving healthy living education over a 12-week period. The primary outcomes measured will include improvements in VO2 peak and 6-minute walk distance. The study is designed to assess the feasibility and preliminary effectiveness of this intervention in enhancing the overall health of prostate cancer patients undergoing treatment.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Be diagnosed with stage II/III/IV prostate cancer
* Be currently undergoing treatment with ADT (intermittent or prolonged)
* Have completed local curative-intent treatment, including prostatectomy or definitive radiation;
* Be \>40 years of age up to 85;
* Be willing to sign an informed consent with HIPAA authorization form;
* Not have any hearing or sight impairments that result in the inability to use the telephone or hear normal conversation;
* Must be able to join an intervention group by personal computer, smartphone or telephone call and should agree to recording of an interview;
* Be without any serious medical condition that precludes safe participation in an exercise program;
* Speak English

Exclusion Criteria:

* Be unable to undergo MRI (i.e., ferromagnetic materials in body, inability to lie flat, claustrophobia);
* Have contraindications to exercise testing;
* Have pre-existing overt cardiovascular disease/heart failure;
* Active illness/infection;
* Hemoglobin \< 7.0 grams/dL
* Platelet count \< 10 x 109/L

Where it's running

• Virginia Commonwealth University Massey Cancer Center
  Richmond, Virginia, United States Recruiting
• Richmond Veterans Affairs Medical Center
  Richmond, Virginia, United States Not yet recruiting

Study contacts

• Principal investigator: Alexander R Lucas, PhD — Virginia Commonwealth University
• Study coordinator: Alexander R Lucas, PhD
• Email: Alexander.Lucas@vcuhealth.org
• Phone: 804 628-6610

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.