How two myoelectric control methods affect attention and daily function for people with below-the-elbow amputation

Comparing the Attentional Demands and Functional Outcomes of Pattern Recognition and Direct Myoelectric Control in People With Transradial Amputation

Not applicable Interventional Virginia Commonwealth University · NCT07075042

This project tests whether pattern recognition control or traditional two-site direct myoelectric control is easier to use and more helpful for adults with below-the-elbow (transradial) limb loss when using a prosthesis.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment32 (estimated)
Ages18 Years and up
SexAll
SponsorVirginia Commonwealth University Academic / other
Locations2 sites (Austin, Texas and 1 other locations)
Trial IDNCT07075042 on ClinicalTrials.gov

What this trial studies

Adults with unilateral transradial amputation who already use a myoelectric prosthesis will be trained to use both pattern recognition control (PRC) and traditional two-site direct control (DC). Participants will use each control method as their primary device for three months, with structured training followed by community and home use and periodic outcome testing. Outcome measures will include functional task performance, measures of attentional demand during prosthesis use, and user-reported ease of use and satisfaction. The crossover design enables direct within-subject comparison between PRC, which uses multiple EMG channels and pattern-classification algorithms, and DC, which relies on two-site EMG amplitude and switching.

Who should consider this trial

Good fit: Adults 18 or older with unilateral transradial limb loss at least six months prior, who have used a myoelectric device for three months or more, wear a prosthesis at least four days per week, can read and write English, and are willing to use each control strategy as their primary device for three months.

Not a fit: People with bilateral limb loss, those less than six months post-amputation, those who discontinued myoelectric prosthesis use for medical or other non-financial reasons, or anyone unable or unwilling to commit to six months of participation may not receive benefit from joining.

Why it matters

Potential benefit: If successful, this could make myoelectric prosthesis control feel more natural, reduce mental effort, and improve day-to-day function for people with transradial limb loss.

How similar studies have performed: Pattern recognition systems are clinically established and prior work suggests they can be more intuitive and support a broader range of motions than two-site direct control, though direct long-term home-use comparisons remain relatively limited.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* 18 years of age or older
* Unilateral transradial limb loss
* At least 6 months since loss
* Previous or current use of a myoelectric device for 3 months or longer
* Use of a prosthesis at least 4 days each week
* Ability to read, write, and understand English
* Willingness to use each control strategy as primary device for 3 months each (6 months commitment total)

Exclusion Criteria:

* Any health condition that would prevent safely completing trial activities
* Discontinued use of a myoelectric prosthesis due to non-financial reasons

Where this trial is running

Austin, Texas and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions AmputationProsthesis UseTransradial AmputationDirect Myoelectric ControlPattern Recognition Controller
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.