Condition

Urinary Tract Infections clinical trials and research

• 28Clinical trials
• 31NIH research projects
• 19Countries

Newest Urinary Tract Infections clinical trials

All recruiting trials (28)

• Gentamicin Irrigation and Suction Ureteral Access in Kidney Stone Surgery

  This trial tests whether using gentamicin-containing irrigation fluid and a suction-enabled ureteral access sheath during retrograde intrarenal surgery (RIRS) can lower fever, SIRS, and sepsis after kidney stone treatment.

  Recruiting Hitit University · Çorum, Çorum and 1 other locations · NCT07655050

• Gepotidacin in Breast Milk of Healthy Lactating Women

  This study will test how gepotidacin behaves in the breast milk of healthy lactating women who are breastfeeding.

  Recruiting Phase 1 GlaxoSmithKline · Las Vegas, Nevada · NCT07645235

• Post-Emergency Antibiotic Optimization for UTI

  In people who come to the emergency department with a suspected urinary tract infection, this study looks at how doctors can adjust antibiotic therapy after urine culture results to use the right antibiotic and reduce overuse.

  Recruiting Centre Hospitalier Intercommunal Creteil · Melun and 2 other locations · NCT07559318

• Prophylactic antibiotics to reduce post-procedure UTIs after urethral bulking

  We’re testing whether giving a preventive antibiotic at the time of urethral bulking can lower the chance of a urinary tract infection after the procedure for women with stress or mixed urinary incontinence.

  Recruiting at 2 sites Phase 4 University of Miami · Miami, Florida and 1 other locations · NCT07501065

• 21-day comprehensive spa care for kidney and urinary conditions

  This program will try a 21-day spa treatment with mineral water baths, drinking cures, exercise and diet for adults 40–70 who have chronic kidney or urinary problems to see if it improves symptoms and kidney health.

  Recruiting Institute of Spa and Balneology, public research institution · Mariánské Lázně, Carlsbad Region · NCT07435844

• Testing single and multiple IV doses of JKN2501 in healthy Chinese adults

  This test gives single and multiple intravenous doses of JKN2501 to healthy Chinese adults to see if it's safe and how the body processes it.

  Recruiting Phase 1 Joincare Pharmaceutical Group Industry Co., Ltd · Changsha, Hunan · NCT07207291

• Nightly nitrofurantoin pills versus a Lactobacillus/low‑dose estriol vaginal tablet to prevent recurrent bladder infections in postmenopausal women

  This trial will try whether nightly nitrofurantoin or a vaginal Lactobacillus/low‑dose estriol tablet (Gynoflor) better prevents recurrent urinary tract infections in postmenopausal women.

  Recruiting Phase 4 Mahidol University · Bangkok, Phayatai Ratchathewi · NCT07186465

• Prediction tool to guide antibiotic decisions for urinary tract infections after ER visits

  This project tests whether a prediction model used at ED discharge can help doctors decide if adult women with a suspected UTI need antibiotics.

  Recruiting University Hospitals Cleveland Medical Center · Cleveland, Ohio · NCT06976125

• Understanding urinary tract infections caused by resistant bacteria

  This study looks at how doctors in the Bas-Rhin region treat urinary tract infections caused by hard-to-treat bacteria to see if there are better ways to help patients.

  Recruiting University Hospital, Strasbourg, France · Strasbourg · NCT06910878

• DNA PCR versus urine culture to diagnose and treat urinary tract infections

  This study will test whether a DNA PCR test instead of a standard urine culture gives faster or more useful results for adults who come to clinic with UTI symptoms.

  Recruiting University Hospitals Cleveland Medical Center · Cleveland, Ohio · NCT06808451

• Comparing intravenous and oral antibiotics for acute infections

  This study tests if oral antibiotics can work just as well as intravenous ones for people in the hospital with acute infections to see if they can shorten hospital stays and lower risks.

  Recruiting at 4 sites University of Southern Denmark · Aabenraa, Southern Denmark and 6 other locations · NCT06715306

• Vaccine for preventing urinary tract infections in adults

  This study is testing a new vaccine to see if it can help prevent urinary tract infections in adults, especially women who often get them.

  Recruiting at 8 sites Phase 1/2 GlaxoSmithKline · Lenexa, Kansas and 7 other locations · NCT06702449

• Evaluating the impact of guidelines on urinary tract infections related to ureteral stents

  This study is testing if following new guidelines for treating urinary tract infections in patients with ureteral stents helps reduce the chances of getting infections again.

  Recruiting Central Hospital, Nancy, France · Nancy, Lorraine · NCT06503588

• Collecting E. Coli Samples from Patients with Recurrent Urinary Tract Infections

  This study is collecting samples of E. coli from patients with recurring urinary tract infections to see how these bacteria behave and why they might keep coming back.

  Recruiting Université Catholique de Louvain · Brussels · NCT05826067

• Ultrasound evaluation for children with their first urinary tract infection

  This study is testing whether kidney ultrasounds are needed for all children with their first urinary tract infection or just for those with certain risk factors.

  Recruiting at 3 sites IRCCS Burlo Garofolo · Florence and 2 other locations · NCT05814250

• Evaluating double voiding to reduce urinary tract infections in kidney transplant recipients

  This study is testing if a technique called double voiding can help kidney transplant recipients reduce their risk of urinary tract infections.

  Recruiting Weill Medical College of Cornell University · New York, New York · NCT05711446

• Fosfomycin for treating antibiotic-resistant urinary tract infections in children

  This study is testing if fosfomycin can help children with antibiotic-resistant urinary tract infections feel better compared to standard treatments.

  Recruiting at 4 sites Phase 3 University of Sydney · Sydney, New South Wales and 4 other locations · NCT05709028

• Treatment of acute urinary tract infections caused by drug-resistant E. coli using a bacteriophage cocktail

  This study is testing a new treatment using a special virus mix to see if it can help people with urinary tract infections caused by tough-to-treat E. coli bacteria.

  Recruiting at 12 sites Phase 2 Locus Biosciences · Fresno, California and 16 other locations · NCT05488340

• Comparing automatic vs. as-needed follow-up care for children after hospitalization

  This study tests whether regular follow-up visits for kids after being in the hospital can help them stay healthy and avoid going back to the hospital, compared to only seeing a doctor when needed.

  Recruiting at 13 sites University of Utah · Phoenix, Arizona and 13 other locations · NCT05471908

• Research on complicated urinary tract infections

  This study is trying to gather information on complicated urinary tract infections to better understand their causes and see if existing medications or new treatments can help people who suffer from them.

  Recruiting European Clinical Research Alliance for Infectious Diseases (ECRAID) · Seville, Sevilla · NCT05458700

• Observational study on urinary tract infections after stent removal

  This study looks at whether removing ureteral stents at home or in a clinic affects the chances of getting urinary tract infections in adults.

  Recruiting University Hospital, Ghent · Ghent, Eastern-Flanders · NCT05329883

• Single dose of amikacin for treating uncomplicated cystitis in the emergency department

  This study tests if a single injection of the antibiotic amikacin can effectively treat uncomplicated bladder infections in women visiting the emergency department.

  Recruiting Maimonides Medical Center · Brooklyn, New York · NCT05227937

• Using pivmecillinam with amoxicillin/clavulanic acid for treating complicated urinary tract infections

  This study is testing if a new combination of two antibiotics, pivmecillinam and amoxicillin/clavulanic acid, can effectively treat complicated urinary tract infections in adults who are switching from intravenous to oral medication.

  Recruiting at 5 sites Phase 3 Lund University · Helsingborg and 4 other locations · NCT05224401

• Using advanced sequencing to improve treatment for urinary tract infections

  This study is testing if new lab techniques can help women with urinary tract infections get better antibiotic treatment, especially when their urine tests show low levels of bacteria.

  Recruiting Phase 4 Wake Forest University Health Sciences · Winston-Salem, North Carolina · NCT05206500

• A large biobank for acute and emergency medicine

  This study is collecting health information and samples from patients with sudden illnesses in the Emergency Department to see if it can help improve treatments and predict how patients will do.

  Recruiting University Medical Center Groningen · Groningen · NCT04615065

• Using hyaluronic acid and chondroitin sulfate to prevent recurrent urinary tract infections in women

  This study is testing whether a combination of hyaluronic acid and chondroitin sulfate can help women who often get urinary tract infections by reducing the number of infections they experience.

  Recruiting at 2 sites Phase 4 University Hospital, Basel, Switzerland · Basel and 1 other locations · NCT04095572

• Digestive tract effects after common antibiotics for urinary infections in young children

  This project will see if common antibiotic treatments for febrile urinary tract infections in children under 3 change their gut bacteria or increase antibiotic-resistant strains.

  Recruiting at 14 sites Centre Hospitalier Intercommunal Creteil · Charenton-le-Pont and 19 other locations · NCT03825874

• Using fosfomycin to treat severely infected patients

  This study is testing if an intravenous antibiotic called fosfomycin can safely help people with serious infections like osteomyelitis and bacterial meningitis feel better.

  Recruiting at 45 sites Infectopharm Arzneimittel GmbH · Hall in Tirol and 49 other locations · NCT02979951

NIH-funded research (31)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• New ways to stop urinary tract infections by blocking bacterial adhesion

  A study to test new methods that prevent bacteria from sticking to urinary tract tissues and devices, potentially stopping infections before they start.

  NIH research University of Washington · Seattle, United States · NIH-11579974

• Hybridization capture sequencing to quickly identify canine urinary pathogens and resistance genes

  A new sequencing approach directly from dog urine aims to rapidly identify bacteria causing urinary infections and their drug-resistance profiles to guide treatment.

  NIH research University of Illinois at Urbana-Champaign · Champaign, United States · NIH-11519326

• Enterococcal Proteases and CAUTI: How the body’s environment activates bacteria to cause infections

  A small grant is exploring how two enzymes from Enterococcus faecalis interact with the urine environment to drive catheter-associated urinary tract infections and why these infections are hard to treat.

  NIH research Marshall University · Huntington, UNITED STATES · NIH-11448148

• Daily nitrofurantoin with or without bladder cauterization to prevent recurrent bladder infections in women

  This study tests two approaches to prevent recurrent bladder infections in women: taking a low-dose antibiotic every day versus adding a bladder cauterization procedure plus the same daily antibiotic.

  NIH research Ut Southwestern Medical Center · Dallas, United States · NIH-11400281

• New bacterial pathway that helps cause bladder infections

  Researchers are exploring how bacteria steal nutrients in the bladder and how the body fights them to help people with urinary tract infections.

  NIH research Columbia University Health Sciences · New York, United States · NIH-11380497

• New oral antifungal for tough Candida UTIs

  A Johns Hopkins team is testing a new oral antifungal medicine called fungerps to treat urinary tract infections caused by azole-resistant Candida fungi.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11378664

• Understanding how bacteria and fungi interact to cause catheter-related urinary infections

  Researchers are studying how common bladder infections linked to catheters happen when bacteria and fungi work together, and what that could mean for better prevention and treatment.

  NIH research University of Notre Dame · Notre Dame, United States · NIH-11373077

• Genetic clues to defensin signaling in urinary tract infections

  Scientists will study how defensins, tiny immune molecules, help fight urinary tract infections in a mouse model to uncover new ways to treat UTIs.

  NIH research University of Texas Dallas · Richardson, United States · NIH-11369052

• Multimodal outpatient antibiotic stewardship to improve UTI care for veterans with neurogenic bladder

  A program to improve how UTIs are diagnosed and treated in veterans with neurogenic bladder who receive care outside hospital settings.

  NIH research VA Eastern Colorado Health Care System · Aurora, UNITED STATES · NIH-11343207

• Best antibiotic choices for urinary tract infections during pregnancy

  This project compares common antibiotic types and treatment lengths to find safer, more effective options for pregnant people with urinary tract infections.

  NIH research Washington University · Saint Louis, United States · NIH-11336811

• New antibiotics for complicated urinary tract infections

  A new class of powerful antibiotics called oxepanoprolinamides is being developed to treat complicated urinary tract infections, especially when usual medicines fail.

  NIH research Kinvard Bio, INC. · Flourtown, United States · NIH-11313278

• 3D-printed urinary catheters that release helpful probiotics to prevent infections

  This project makes catheter tubing that slowly releases Lactobacillus probiotics to help prevent catheter-associated urinary tract infections in adults.

  NIH research Washington University · Saint Louis, United States · NIH-11304580

• Using antibodies to prevent and treat bladder infections

  This project uses antibody and vaccine-style approaches to help people—especially women—who get frequent urinary tract infections from E. coli.

  NIH research Washington University · Saint Louis, United States · NIH-11257271

• Reducing unnecessary antibiotic use for urinary tract infections

  This study is looking at ways to better diagnose urinary tract infections (UTIs) so that people don’t get prescribed antibiotics they don’t need, helping to keep antibiotics effective for everyone.

  NIH research Baltimore VA Medical Center · Baltimore, United States · NIH-11194229

• Understanding Defensins in Urinary Tract Infections and Pain

  This work explores how natural defense proteins called defensins affect urinary tract infections and related pain, aiming to find better ways to help patients.

  NIH research University of Texas Dallas · Richardson, United States · NIH-11140990

• Quick urine test to show which antibiotics work for urinary tract infections

  A fast lateral-flow urine test designed to tell doctors which antibiotics will work for people with urinary tract infections during or shortly after a clinic visit.

  NIH research Latde Diagnostics Corp. · Northampton, United States · NIH-11134666

• Improving urine test accuracy to reduce unnecessary antibiotic use.

  This study is working to make urine tests for urinary tract infections more accurate by helping patients understand how to collect their samples correctly, especially if they face language or understanding challenges, so they can get the right treatment without unnecessary antibiotics.

  NIH research Baylor College of Medicine · Houston, United States · NIH-11087571

• Finding the best antibiotics for treating urinary tract infections in pregnant women

  This study is looking to find the best ways to treat urinary tract infections in pregnant women to keep both moms and babies healthy, so doctors can give the safest and most effective antibiotics.

  NIH research Washington University · Saint Louis, United States · NIH-11082305

• Comparing treatments for urinary tract infections in pregnant women

  This study is looking at how safe and effective different medications are for treating urinary tract infections in pregnant women, and it aims to help doctors choose the best treatment based on whether or not patients have symptoms.

  NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-11076182

• Using 3D printing to create catheters that prevent urinary tract infections

  This study is testing a new type of catheter that uses friendly bacteria to help prevent urinary tract infections for people who need to use catheters, making it a safer option for them.

  NIH research Washington University · Saint Louis, United States · NIH-11065501

• A quick test to determine the right antibiotics for urinary tract infections

  This study is working on a quick and fair test to help doctors find the best antibiotics for treating urinary tract infections, making it easier for patients to get the right treatment faster, especially in places with fewer resources.

  NIH research Latde Diagnostics Corp. · Northampton, United States · NIH-11006225

• Investigating urinary tract infections caused by resistant bacteria in women

  This study is looking at urinary tract infections (UTIs) caused by a specific type of bacteria in women from different backgrounds to find out what factors might increase the risk of these infections and how to prevent them better.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-10992196

• Using antibodies to prevent and treat urinary tract infections

  This study is working on a new vaccine that could help women who often get urinary tract infections by teaching their bodies to fight off the bacteria that cause these infections.

  NIH research Washington University · Saint Louis, United States · NIH-10975366

• Understanding how defensins affect urinary tract infections

  This study is looking at how certain natural proteins in the body, called defensins, help fight off urinary tract infections (UTIs) caused by specific bacteria, with the hope of finding better treatments for people who struggle with these infections and don’t respond well to antibiotics.

  NIH research University of Texas Dallas · Richardson, United States · NIH-10936336

• New treatments to stop Uropathogenic E. coli from causing urinary tract infections

  This study is looking for new ways to treat urinary tract infections by blocking the germs that cause them from sticking to your urinary tract, using special tiny proteins that could help keep you healthy without harming the good bacteria in your body.

  NIH research University of Utah · Salt Lake City, United States · NIH-10933568

• Understanding how vaginal estrogen therapy helps prevent urinary tract infections in postmenopausal women

  This study is looking into why some postmenopausal women find relief from recurring urinary tract infections when using vaginal estrogen therapy, focusing on the good bacteria in their bodies and how estrogen affects their immune system, to help improve treatment options for those dealing with these infections.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-10900706

• Understanding how the bladder protects against urinary tract infections

  This study is looking at how a part of your bladder helps fight off urinary tract infections (UTIs) and how a specific protein called IL-6 can help clear out harmful bacteria, with the hope of finding new ways to prevent and treat UTIs, especially as antibiotics become less effective.

  NIH research Research Inst Nationwide Children's Hosp · Columbus, United States · NIH-10886954

• Using viruses that target bacteria to treat urinary tract infections

  This study is looking at how special viruses called bacteriophages can help treat urinary tract infections caused by tough bacteria that don't respond to regular antibiotics, and it aims to find a new way to help people feel better and reduce the chances of getting UTIs again.

  NIH research Baylor College of Medicine · Houston, United States · NIH-10817688

• Developing smart catheters to prevent urinary tract infections

  This study is testing a new type of catheter designed to help prevent urinary tract infections by using special surfaces that stop bacteria from growing, making it safer and more effective for patients who need catheters.

  NIH research Syracuse University · Syracuse, United States · NIH-10735881

• New ways to prevent urinary tract infections

  This study is looking for new ways to treat urinary tract infections caused by tough bacteria, and it’s for anyone who has struggled with these infections; researchers are testing a special antibody that might stop the bacteria from sticking to the urinary tract, helping to create better treatments.

  NIH research University of Washington · Seattle, United States · NIH-10705027

• Understanding how the bladder protects against urinary tract infections

  This study is looking at how a part of your bladder helps fight off urinary tract infections (UTIs) by focusing on a substance called IL-6, with the goal of finding new ways to prevent and treat UTIs, especially as antibiotics become less effective.

  NIH research Research Inst Nationwide Children's Hosp · Columbus, United States · NIH-10615681

Related topics

Quick answers

How many Urinary Tract Infections clinical trials are recruiting right now?

28, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 19 countries. The most sites are in United States (10 trials), France (4 trials), Belgium (2 trials), Italy (2 trials), Netherlands (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 4, Phase 3: 2, Phase 1: 2, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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