Collecting E. Coli Samples from Patients with Recurrent Urinary Tract Infections
Official title: Systematic Analysis of Bacterial Multidrug Tolerance in Longitudinal Isolates of Patients That Are Prone to Developing Urinary Tract Infections
Run by Université Catholique de Louvain · NCT05826067 · Data updated 2026-11-12
This study is collecting samples of E. coli from patients with recurring urinary tract infections to see how these bacteria behave and why they might keep coming back.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 45 (estimated) |
| Sponsor | Université Catholique de Louvain Academic / other |
| Locations | 1 site (Brussels) |
| Status | Recruiting |
| Started | April 20, 2023 |
| Main results expected | December 31, 2025 |
| Study ends | December 31, 2025 |
| Registry record updated | December 10, 2024 |
| Trial ID | NCT05826067 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include hospitalized or ambulatory patients diagnosed with urinary tract infections caused by E. coli, particularly those with neurological disorders or requiring catheterization.
✕Probably not a fit
Patients who refuse treatment, are non-compliant with therapy, pregnant, or do not consent to participate may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to collect clinical isolates of Escherichia coli from patients experiencing recurrent urinary tract infections. Samples will be gathered during routine medical procedures from patients with various conditions, including those with suprapubic or nephrostomy catheters. The study seeks to understand the persistence of E. coli strains in natural settings, which may contribute to chronic infections and antibiotic resistance. Detailed medical histories will be compiled to assess the impact of previous antibiotic treatments on infection recurrence.
Why it matters
Potential benefit: If successful, this study could lead to improved understanding and treatment strategies for recurrent urinary tract infections caused by E. coli.
How similar studies have gone: While studies on E. coli and urinary tract infections exist, this specific approach focusing on natural strains and persistence is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * patients hospitalized for urinary tract infection, with or without neurological disorders (spina bifida, MS, paraplegic patients) or ambulatory patients diagnosed with a urinary tract infection when the identified causative agent is E. coli * patients who have or are planned to undergo the insertion of a suprapubic catheter * patients who have or are planned to undergo the insertion a nephrostomy catheter Exclusion Criteria: patients * refusing the planned treatment * with therapy compliance * pregnant women * who do not consent to participate
Where it's running
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Cliniques universitaires Saint Luc
Brussels, Belgium Recruiting
Study contacts
- Study coordinator: Françoise Van Bambeke, PhD
- Email: francoise.vanbambeke@uclouvain.be
- Phone: +32-2-764
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.