Condition

Bacteremia clinical trials and research

• 16Clinical trials
• 14NIH research projects
• 17Countries

Newest Bacteremia clinical trials

All recruiting trials (16)

• UllCORE BSI Test for Bloodstream Infections

  This study tests whether the UllCORE BSI Test can correctly detect bloodstream infection pathogens and resistance markers from whole blood in people with suspected infection or sepsis.

  Recruiting Deepull Diagnostics S.L. · Orange, California and 19 other locations · NCT07859852

• Beta-lactam plus levofloxacin for streptococcal bacteremia

  This trial tests whether adding levofloxacin to standard beta-lactam therapy helps adults with streptococcal bacteremia see better outcomes.

  Recruiting at 2 sites Phase 4 Mahidol University · Bangkok and 3 other locations · NCT07240077

• Blood cultures from arterial lines: does it change contamination, bacteremia detection, and how much blood is drawn?

  This study tests whether drawing blood cultures from arterial lines affects contamination rates, how well bacteremia is detected, and the volume of blood collected in ICU patients.

  Recruiting Meir Medical Center · Kfar Saba · NCT07183410

• New care guideline for infants 60 days and younger with fever in Sweden

  This project will test a new guideline to see if infants 60 days or younger with fever can safely avoid many invasive tests, hospital stays, and broad antibiotics compared with usual care.

  Recruiting at 9 sites Region Skane · Gothenburg and 10 other locations · NCT07134751

• GRADY: a computer tool to detect early sepsis and gram-negative bloodstream infection in ICU patients

  The GRADY tool will be tested to see if routine vital signs and lab results can detect early sepsis and gram-negative bloodstream infection in adult ICU patients.

  Recruiting Sisli Hamidiye Etfal Training and Research Hospital · Seyrantepe, Istanbul · NCT07126106

• Linezolid added to standard care for Staphylococcus aureus bloodstream infection

  This trial will test whether giving linezolid in addition to usual antibiotics helps adults hospitalized with Staphylococcus aureus bloodstream infections.

  Recruiting at 12 sites University Hospital, Basel, Switzerland · Aarau, Canton of Aargau and 11 other locations · NCT06958835

• Examining biofilm in arterial catheters in ICU patients

  This study looks at the germs that build up on arterial catheters in ICU patients to see how they might cause infections and find better ways to prevent them.

  Recruiting at 2 sites Centre Hospitalier William Morey - Chalon sur Saône · Dijon, Bourgogne-Franche-Comté and 1 other locations · NCT06838598

• Monitoring antimicrobial resistance in the Democratic Republic of Congo

  This study is testing how well we can track antibiotic resistance in a hospital in Kinshasa, DRC, to better understand bacterial infections and improve treatment for patients.

  Recruiting University of Oxford · Kinshasa, Kinshasa City · NCT06821282

• Comparing two antibiotics for treating Staphylococcus aureus bloodstream infections

  This study is testing whether benzylpenicillin works better than cloxacillin for treating bloodstream infections caused by Staphylococcus aureus in adults.

  Recruiting Phase 4 Region Skane · Lund · NCT06726395

• Echocardiography versus no echocardiography for Staphylococcus aureus bloodstream infection with VIRSTA score <3

  This trial tests whether it is safe to skip routine echocardiography in adults hospitalized with Staphylococcus aureus bloodstream infection who have a VIRSTA score under 3.

  Recruiting Assistance Publique - Hôpitaux de Paris · Paris · NCT06457386

• Improving vancomycin dosing for young infants with infections

  This study is testing a new way to give the right amount of vancomycin to young infants with infections to help them get better faster.

  Recruiting at 2 sites Phase 4 Murdoch Childrens Research Institute · Melbourne, Victoria and 3 other locations · NCT05770622

• Improving oral hygiene to reduce risk of infective endocarditis

  This study tests if better oral hygiene, through dental cleaning and education, can help reduce bacteria in the blood for people at risk of infective endocarditis.

  Recruiting at 3 sites Wake Forest University Health Sciences · Boston, Massachusetts and 5 other locations · NCT05721781

• Using pivmecillinam with amoxicillin/clavulanic acid for treating complicated urinary tract infections

  This study is testing if a new combination of two antibiotics, pivmecillinam and amoxicillin/clavulanic acid, can effectively treat complicated urinary tract infections in adults who are switching from intravenous to oral medication.

  Recruiting at 5 sites Phase 3 Lund University · Helsingborg and 4 other locations · NCT05224401

• Comparing two antibiotics for treating bloodstream infections from resistant bacteria

  This study is testing if a new antibiotic called piperacillin-tazobactam works as well as meropenem for treating bloodstream infections caused by resistant bacteria in adults.

  Recruiting at 14 sites Phase 4 Rambam Health Care Campus · Calgary, Alberta and 13 other locations · NCT03671967

• Using fosfomycin to treat severely infected patients

  This study is testing if an intravenous antibiotic called fosfomycin can safely help people with serious infections like osteomyelitis and bacterial meningitis feel better.

  Recruiting at 45 sites Infectopharm Arzneimittel GmbH · Hall in Tirol and 49 other locations · NCT02979951

• Pneumococcal infection surveillance in Lebanon

  This study is trying to find out which types of bacteria cause serious infections like pneumonia in Lebanon and how well current vaccines and antibiotics work against them.

  Recruiting American University of Beirut Medical Center · Beirut · NCT00901602

NIH-funded research (14)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Collaborative AI for safer, faster bacteremia care

  A physician-centered AI system is being built to help diagnose and treat bloodstream infections more accurately and safely, with the goal of reducing sepsis deaths.

  NIH research University of Central Florida · Orlando, United States · NIH-11579169

• Rapid pathogen ID and antibiotic testing for bacteremia using immune capture, microfluidics, and AI

  A fast, AI-assisted diagnostic system will identify bacteria in blood and determine which antibiotics are likely to work, helping doctors treat bacteremia sooner.

  NIH research Southern Illinois University Carbondale · Carbondale, United States · NIH-11445199

• Predicting which febrile kids with sickle cell disease are at low risk for bacteremia

  A small, patient-facing prediction rule is being developed to help doctors decide which febrile children with sickle cell disease really need aggressive testing and antibiotics.

  NIH research Yale University · New Haven, United States · NIH-11441291

• Multimodal antibody therapy to treat Staphylococcus aureus bloodstream infections

  A hospital-focused immunotherapy approach uses a mix of antibodies to help fight blood infections from Staphylococcus aureus by blocking immune evasion and bacterial growth.

  NIH research Abvacc, INC. · Rockville, United States · NIH-11399169

• Defining how macrophages fight Klebsiella in the blood

  This grant studies how innate immune cells called macrophages protect against Klebsiella pneumoniae bloodstream infections to help reduce sepsis mortality.

  NIH research University of Minnesota · Minneapolis, United States · NIH-11351003

• Epigenomic clues and immune context in stubborn MRSA bloodstream infections

  Researchers are studying why some MRSA bloodstream infections persist despite antibiotics and how the immune system and bacterial DNA packaging (epigenetics) influence this, with the goal of better treatments.

  NIH research Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center · Torrance, United States · NIH-11350993

• Liposome-delivered rebamipide as an add-on treatment for Staphylococcus aureus bacteremia

  A biotech company is testing a liposome-formulated rebamipide to help the body fight Staphylococcus aureus bloodstream infections alongside standard antibiotics.

  NIH research Cmtx Biotech, INC. · Kings Park, United States · NIH-11314909

• Understanding how immune cells fight Klebsiella pneumoniae infections in the bloodstream

  This study is looking at how certain immune cells called macrophages help fight off infections from a bacteria called Klebsiella pneumoniae, especially when it gets into the bloodstream, and it aims to find ways to boost our body's ability to tackle these serious infections.

  NIH research University of Minnesota · Minneapolis, United States · NIH-11313050

• Fast blood test to quickly find bloodstream bacteria and the best antibiotics

  This project is creating a fast blood test that finds bacteria in the blood, identifies the species, measures how many are present, and shows which antibiotics are likely to work for people with suspected bacteremia.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11241965

• Understanding how MRSA bacteria survive in the bloodstream despite antibiotic treatment

  This study is looking into why MRSA, a tough bacteria that can cause infections in the blood, sometimes sticks around even when antibiotics should work, and it's aimed at helping patients by finding better ways to treat these stubborn infections.

  NIH research Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center · Torrance, United States · NIH-11091668

• Understanding why some Staphylococcus aureus infections don't respond to antibiotics

  This study is looking into why some people with a serious bloodstream infection caused by Staphylococcus aureus don't get better, by examining the bacteria and patient information to find out how the bacteria might be changing and resisting treatment, with the hope of finding better ways to help those affected.

  NIH research Duke University · Durham, United States · NIH-11032978

• A new method for quickly diagnosing bacterial infections in the bloodstream.

  This study is working on a fast and easy way to find out if you have bacteria in your blood, which can cause serious infections, so that you can get the right treatment much quicker than with current methods.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11021010

• Investigating infections caused by antibiotic-resistant enterococci

  This study is looking at how infections from hard-to-treat bacteria called vancomycin-resistant enterococci (VRE) affect people with weakened immune systems or other health problems, and it aims to find better ways to treat these infections to help patients feel better.

  NIH research Methodist Hospital Research Institute · Houston, United States · NIH-10849696

• Understanding how non-typhoidal Salmonella spreads in the bloodstream

  This study is looking at how a type of bacteria called non-typhoidal Salmonella can cause serious infections in the bloodstream, and it aims to find new ways to treat these infections by understanding how the bacteria avoid the immune system and spread in the body.

  NIH research University of Louisville · Louisville, United States · NIH-10580145

Related topics

Quick answers

How many Bacteremia clinical trials are recruiting right now?

16, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 17 countries. The most sites are in Sweden (3 trials), France (3 trials), Israel (2 trials), Germany (2 trials), Italy (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 4, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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