Observational study on urinary tract infections after stent removal
Official title: Multicentric Study on Infections of the Urinary Tract After Stent Removal (MINUS-trial).
Run by University Hospital, Ghent · NCT05329883 · Data updated 2026-11-12
This study looks at whether removing ureteral stents at home or in a clinic affects the chances of getting urinary tract infections in adults.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 1000 (estimated) |
| Sponsor | University Hospital, Ghent Academic / other |
| Locations | 1 site (Ghent, Eastern-Flanders) |
| Status | Recruiting |
| Started | November 25, 2021 |
| Main results expected | December 31, 2025 |
| Study ends | December 31, 2025 |
| Registry record updated | January 15, 2025 |
| Trial ID | NCT05329883 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18 and older who have had a ureteral stent placed during an endoscopic procedure and have a negative urine culture prior to stent removal.
✕Probably not a fit
Patients with permanent indwelling catheters, pregnant individuals, or those with a recent history of urinary tract infections may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The MINUS-trial is a multicentric prospective observational study that aims to gather data on the incidence of urinary tract infections (UTIs) following the removal of ureteral stents in patients aged 18 and older. Participants will have their stents removed either in an outpatient setting or at home, with or without antibiotic prophylaxis based on the standard care of the participating center. Urine samples will be collected before stent removal, and patients will complete a questionnaire to report any UTI symptoms post-removal. The study seeks to identify risk factors for post-stent removal UTIs and compare infection rates between different removal methods.
Why it matters
Potential benefit: If successful, this study could lead to improved guidelines for antibiotic use and reduced incidence of urinary tract infections after stent removal.
How similar studies have gone: While there is limited data on this specific approach, the study addresses a significant gap in current guidelines regarding antibiotic prophylaxis for stent removal.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patient aged 18 years or above * Stent placed during endoscopic procedure * A negative urine culture (UC) pre-operatively with a single dose of antibiotic prophylaxis peri-operatively * Stent removal is planned in outpatient setting of by the patient by using a string. * Able and willing to provide consent Exclusion Criteria: * Permanent indwelling catheter (transurethral catheter, suprapubic catheter, nephrostomy tubes) * Pregnant patients * Patient performing clean intermittent (self-)catheterization * Recent history (\<3 months) of demonstrated UTI
Where it's running
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University Hospital Ghent
Ghent, Eastern-Flanders, Belgium Recruiting
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.