Ultrasound evaluation for children with their first urinary tract infection
Official title: Is Ultrasonography Mandatory in All Children at Their First Febrile Urinary Tract Infection?
Run by IRCCS Burlo Garofolo · NCT05814250 · Data updated 2026-11-12
This study is testing whether kidney ultrasounds are needed for all children with their first urinary tract infection or just for those with certain risk factors.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 2 Months to 3 Years |
| Sex | All |
| Enrollment | 20 (estimated) |
| Sponsor | IRCCS Burlo Garofolo Academic / other |
| Drugs / interventions | radiation |
| Locations | 3 sites (Florence and 2 other locations) |
| Status | Recruiting |
| Started | June 13, 2022 |
| Main results expected | March 31, 2025 |
| Study ends | March 31, 2028 |
| Registry record updated | June 12, 2024 |
| Trial ID | NCT05814250 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are children experiencing their first episode of febrile urinary tract infection who are scheduled for kidney ultrasound.
✕Probably not a fit
Patients with previous urinary tract infections or known congenital anomalies of the kidney and urinary tract may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to assess the role of kidney ultrasound (KUS) in children experiencing their first febrile urinary tract infection (fUTI). It examines whether routine KUS is necessary for all children or if it should be reserved for those with specific risk factors, given that current guidelines are not based on strong evidence. The study will include children who have had their first episode of fUTI and will undergo KUS, while excluding those with prior UTIs or known kidney anomalies. The findings could help refine guidelines for the management of fUTIs in pediatric patients.
Why it matters
Potential benefit: If successful, this study could lead to more tailored and effective management strategies for children with febrile urinary tract infections.
How similar studies have gone: Other studies have suggested varying approaches to the use of kidney ultrasound in similar contexts, indicating that this area is still under investigation.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: \- Patient with first episode of fUTI that subsequently do KUS. Exclusion Criteria: * patients with previous episodes of UTIs * patients on antibiotic prophylaxis * previous finding of malformative uropathies or cystic disease * prenatal diagnosis of CAKUT with the following parameters: Presence of oligohydramnios, alterations in renal number, location and echo structure, bladder alteration, dilations of the renal pelvis and ureters
Where it's running
-
AOU Meyer IRCCS
Florence, Italy Recruiting -
IRCCS Policlinico Cà Granda
Milan, Italy Recruiting -
IRCCS materno infantile Burlo Garofolo
Trieste, Italy Recruiting
Study contacts
- Study coordinator: Marco Pennesi, MD
- Email: marco.pennesi@burlo.trieste.it
- Phone: +39 040.3785.263
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.