A quick test to determine the right antibiotics for urinary tract infections
Official title: Rapid, equitable, lateral flow-based antibiotic susceptibility testing for urinary tract infections
Funded at Latde Diagnostics Corp. · NIH-11006225 · Data updated 2026-11-12
This study is working on a quick and fair test to help doctors find the best antibiotics for treating urinary tract infections, making it easier for patients to get the right treatment faster, especially in places with fewer resources.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Latde Diagnostics Corp. NIH-funded |
| Lab location | 1 site (Northampton, United States) |
| Project start | July 8, 2024 |
| Project end | June 30, 2026 |
| Funding year | 2024 |
| Award (this year) | $299,170 |
| NIH project number | 1R43AI186702-01 |
| Project ID | NIH-11006225 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals experiencing urinary tract infections, particularly women and those from low socioeconomic backgrounds.
✕Less likely to help
Patients with UTIs who are already receiving effective treatment or those with conditions unrelated to antibiotic susceptibility may not benefit from this research.
What this research studies
This research aims to develop a rapid and equitable test for antibiotic susceptibility in urinary tract infections (UTIs), which affects millions of patients each year. The test is designed to be used in outpatient and resource-limited settings, allowing healthcare providers to quickly identify the most effective antibiotics for treatment. By reducing the time it takes to get results, this approach seeks to minimize unnecessary delays in therapy and the risk of complications from UTIs. The goal is to improve patient outcomes while also addressing the growing issue of antibiotic resistance.
Why it matters
Potential benefit: If successful, this research could lead to faster and more effective treatment for patients suffering from urinary tract infections.
How similar studies have gone: Other research has shown promise in developing rapid antibiotic susceptibility tests, but this specific approach is novel and aims to address significant gaps in current UTI diagnostics.
Where this research is happening
-
Latde Diagnostics Corp.
Northampton, United States Active
Researchers
- Principal investigator: Melzer, Emily S — Latde Diagnostics Corp.
- Study coordinator: Melzer, Emily S
Related research
Other NIH-funded projects on the same topics.
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New ways to stop urinary tract infections by blocking bacterial adhesion
A study to test new methods that prevent bacteria from sticking to urinary tract tissues and devices, potentially stopping infections before they start.
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Hybridization capture sequencing to quickly identify canine urinary pathogens and resistance genes
A new sequencing approach directly from dog urine aims to rapidly identify bacteria causing urinary infections and their drug-resistance profiles to guide treatment.
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Enterococcal Proteases and CAUTI: How the body’s environment activates bacteria to cause infections
A small grant is exploring how two enzymes from Enterococcus faecalis interact with the urine environment to drive catheter-associated urinary tract infections and why these infections are hard to treat.
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Daily nitrofurantoin with or without bladder cauterization to prevent recurrent bladder infections in women
This study tests two approaches to prevent recurrent bladder infections in women: taking a low-dose antibiotic every day versus adding a bladder cauterization procedure plus the same daily antibiotic.
-
New bacterial pathway that helps cause bladder infections
Researchers are exploring how bacteria steal nutrients in the bladder and how the body fights them to help people with urinary tract infections.
-
New oral antifungal for tough Candida UTIs
A Johns Hopkins team is testing a new oral antifungal medicine called fungerps to treat urinary tract infections caused by azole-resistant Candida fungi.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.